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Headlines > January 2007

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31-Jan-2007

New cancer target could be as important as VEGF

31-Jan-2007 - Scientists have discovered a new mechanism that dictates how many new blood vessels grow in the body, opening up the possibility of a new class of powerful anti-cancer drugs that...

Big pharma backs pollen-based drug delivery

31-Jan-2007 - A team of researchers in the UK have come up with a novel drug delivery system using pollen-based microcapsules to encapsulate the active ingredients, opening up whole new avenues for...

Contract manufacturing news in brief

31-Jan-2007 - Hospira, Laureate Pharma, QSV Biologics and Cook Pharmacia all bagged new contract manufacturing deals this week.

New growth medium product to ease pharma QC

31-Jan-2007 - Microbiology specialists Oxoid have added a new growth medium product to their catalogue of microbiological culture media, for use in aseptic process simulations.

Pharsight says software makes bioequivalence testing easy

31-Jan-2007 - Software provider Pharsight has launched an add-on for its graphical drug modelling method to serve in bioequivalence testing, promising to reduce test failure.

'Unanticipated problems' in trials must be reported, says HHS

31-Jan-2007 - The Department of Health and Human Services (HHS) has released updated guidelines on clinical trial reporting requirements in the US.

30-Jan-2007

Adderall drives pharma division at Johnson Matthey

30-Jan-2007 - Johnson Matthey has announced a reassuring business update ahead of its 31 March year-end, suggesting that Adderall is the driving force behind a recovery in its pharmaceutical materials business.

Lentigen enters disposables market to cut production time

30-Jan-2007 - Viral vector manufacturer Lentigen has entered into a collaboration with Wave Biotech to gain access to disposable process and equipment expertise, which ties in with a shift in the bioprocess...

Merck-Serono launches electronic growth hormone injection device

30-Jan-2007 - Merck-Serono today announced the launch of easypod, the first electronic growth hormone injection device.

Companies combine to create high-speed robot

30-Jan-2007 - Two companies have teamed-up to create what they claim is one of the world's fastest robotic packagers.

Xcellerex receives $20m boost for disposable manufacturing tech

30-Jan-2007 - US-based firm Xcellerex yesterday announced it has completed the second half of a $20m (€15.4m) financing deal, raising $11m to speed up commercialisation of its innovative disposable manufacturing technology for...

Verona Pharma picks UK firm for outsourcing

30-Jan-2007 - UK biotech company Verona Pharma has contracted fellow UK firm Onyx to manufacture supplies of its new hay fever drug candidate for forthcoming preclinical and clinical studies.

29-Jan-2007

Rexam readies safety device for injectables market

29-Jan-2007 - France-based Rexam Pharma is gearing up to launch a safety add-on device that fits on to prefilled syringes to help drugmakers comply with recent legislations designed to prevent needlestick injuries.

Third protein successfully expressed in transgenic chicken eggs

29-Jan-2007 - Researchers have managed to successfully express human interferon alpha-2a in the egg whites of eggs laid by their flock of transgenic hens.

BioProgress completes NRobe restructuring

29-Jan-2007 - BioProgress are set to speed up commercialisation of NRobe, their solid oral dose system, following completion of a restructuring agreement with Magenta Oral Dose Design.

Spectroscopy sees through packaging to thwart drug fakers

29-Jan-2007 - UK based researchers have added another dimension to anti-counterfeiting with an alternative Raman imaging method that is powerful enough to detect fake drugs without opening the package.

Cardinal sells drug manufacturing biz and doubles Q2 profit

29-Jan-2007 - Cardinal Health is about to sell its drug manufacturing arm to an international private investment firm, only two months after announcing its decision to divest the segment, while its second...

26-Jan-2007

Cancer genes lost in translation

26-Jan-2007 - Scientists have discovered a new strategy for fighting cancer that makes the genes responsible for tumour growth get lost in translation.

PerkinElmer increases R&D spending

26-Jan-2007 - Increased research and development (R&D) spending masks strong revenue growth by PerkinElmer's life and analytical sciences division.

Predicting the relevance of genetic mutations

26-Jan-2007 - Scientists have published a website that could aid the quest for personalised medicine by predicting which genetic mutations make an individual susceptible to disease.

Pharma sales fuel Waters resurgence

26-Jan-2007 - Waters posted an 11 per cent yearly sales increase on the back of increasing demand from the pharmaceutical industry, generic houses and outsourcing laboratories.

25-Jan-2007

Lonza scores 18 per cent net profit on biopharma strategy

25-Jan-2007 - Swiss chemicals firm and contract manufacturer Lonza has announced 18 per cent rise in net profit in 2006 rising to CHF 222m (€137.4), fuelled by its strategic move into biopharmaceuticals.

Rexam unveils RFID-tagged pill bottles

25-Jan-2007 - Packaging giant Rexam has fixed a radio frequency identification (RFID) chip in pharmaceutical bottles in response to Food and Drug Administration (FDA) recommendations to make use of the technology to...

Bayer licenses delivery tech for wound care products

25-Jan-2007 - Finnish company DelSitech has signed a license agreement with Bayer Innovation, a subsidiary of the Germany's Bayer group, in a deal that could lead to the creation of a new...

Vetter gets green light for new manufacturing plant

25-Jan-2007 - Germany's Vetter Pharma-Fertigung has announced it has obtained a manufacturing license for its new facility which will expand its services by adding vial filling for lyophilised (freeze-dried) products to its...

24-Jan-2007

Oral flu vaccine on the horizon in Russia

24-Jan-2007 - Russian researchers have developed an intranasal influenza vaccine using a novel adjuvant technology, with plans to develop what could become the first tablet flu vaccine formulation.

Disappointing year for Whatman

24-Jan-2007 - In a turbulent year, Whatman has failed to meet its projected revenue target by 1-3 per cent and changed its management but resolved litigation that has been hanging over the...

QSV inks two clinical trial manufacturing contracts

24-Jan-2007 - Canadian contract manufacturer QSV Biologics has signed two manufacturing deals in as many weeks, strengthening its position in the Phase II and III clinical supplies arena.

Patching up Alzheimer's safely

24-Jan-2007 - US-based researchers have developed a transdermal vaccine for Alzheimers disease which has been shown to clear brain-damaging amyloid plaques in preclinical studies, offering hope to millions of sufferers worldwide.

23-Jan-2007

Rexam's desiccated caps - Evipharm and Secupharm - enters market

23-Jan-2007 - Rexam has introduced two new desiccant caps - Evipharm & Secupharm - that use a filled in-line silica gel as a desiccant to improve shelf life of the drug.

Saltigo gets €40m investment boost from Lanxess

23-Jan-2007 - German fine chemicals company Saltigo is benefiting from a cash injection from its parent company, Lanxess. The German firm is earmarking €30m for plant modernisation at its subsidiary, and a...

Pfizer axes jobs and closes plants

23-Jan-2007 - Pfizer has announced it will axe 10,000 jobs and close facilities in a further effort to save on costs; the move comes in the face of patent expiries for their...

'Large' nanoparticles find loophole in human mucus

23-Jan-2007 - US-based researchers have proven that 'large' nanoparticles can pass through human mucus, which means that they could serve as sustained-release carriers for drugs treating diseases affecting the mucous membranes, such...

Cobra to enter RNAi delivery arena with Cequent

23-Jan-2007 - UK contract manufacturer Cobra will use its antibiotic-free technology to bring a start-up's new RNAi-based bowel tumour treatment to the clinic up to three months ahead of schedule.

Altea's skin patches set to spread transdermal drug delivery

23-Jan-2007 - Novel transdermal patch products for two protein drugs could be on the horizon as Altea Therapeutics announces research agreements with two 'large' pharmaceutical companies.

22-Jan-2007

Workhorse analytical tools to reduce human errors

22-Jan-2007 - Agilent Technologies has signed an agreement with Groton Biosystems to co-market measuring solutions for the pharmaceutical industry, as the Process Analytical Technology (PAT) initiative gains popularity among drug manufacturers constantly...

SciGen aims for a share of the multibillion hep B vaccine market

22-Jan-2007 - Biopharmaceutical firm SciGen has invested $30m (€23.2m) in a hepatitis B vaccine manufacturing plant in Israel, expecting to capture up to 15 per cent of the global market during a...

Sweet toothed bacteria combat gut disorders

22-Jan-2007 - Researchers at the University of Leeds have genetically modified a common gut bacterium to respond to a sugar and produce a treatment for Inflammatory Bowel Disease (IBD).

Novo signs up for Crucell's STAR tech

22-Jan-2007 - Dutch biotech Crucell last week announced it had signed a research licence agreement with Novo Nordisk for the company's STAR technology.

Breakthrough in controlled release drug delivery

22-Jan-2007 - New French research into biodegradable polymers is opening up the door to controlled release treatments for a broader range of drugs, potentially doing away with traditional delivery methods of a...

19-Jan-2007

'Global centre of microarray excellence'

19-Jan-2007 - Oxford Gene Technology and Agilent are to collaborate to develop a global centre of microarray excellence focused on new and emerging applications.

Competitors fill void left by CodeLink exit

19-Jan-2007 - Agilent, Illumina, NimbleGen and Oxford Gene Technology have stepped into the breach caused by GE Healthcare's decision to scrap its CodeLink arrays.

18-Jan-2007

Multi-tasking software "harmonises" regulatory affairs

18-Jan-2007 - US-based Blue Mountain has launched an integrated, comprehensive software package to help life sciences companies manage their assets, cutting out the need for individual software.

FDA cuts cattle material in latest BSE precautions

18-Jan-2007 - More cattle-derived materials used in the production of medical products are due to be banned in the US Food and Drug Administration's (FDA) latest steps to protect against mad cow...

Senopsys offers 'mouth-watering' services to pharma industry

18-Jan-2007 - A new player has entered the pharma formulation development services arena, offering technologies used in the food industry to improve drug palatability.

Dose-sparing strategies for pandemic influenza

18-Jan-2007 - Drug giants Novartis and GlaxoSmithKline (GSK) have been awarded contracts with the US government to develop adjuvant technology for pandemic influenza, to potentially increase the number of doses to be...

Breakthrough in plant seeds for drug production

18-Jan-2007 - Researchers in Belgium have succeeded in using plant seeds to produce high yields of proteins that bear a strong resemblance to human antibodies, thus bringing the possibility of using plant...

17-Jan-2007

Injunction latest snag in FDA pedigree fiasco

17-Jan-2007 - A federal court judge has imposed a temporary injunction against the US Food and Drug Administration (FDA) over the organisation's drug 'pedigree' requirements, on the basis that the regulations leave...

Reformulation trend capturing pharma

17-Jan-2007 - More and more drug makers are turning to reformulation to prolong the lifecycle of their top sellers and protect precious revenue from generic copies, as well as supplement dwindling pipelines.

Sale of Owens-Illinois plastics business on the cards

17-Jan-2007 - The world's largest glass container manufacturer is considering hiving off its plastics packaging business as it reviews strategic options for the division.

Celsis hopes for new business from FDA recognition

17-Jan-2007 - The US Food and Drug Administration has accepted two Celsis drug master files (DMFs) that could increase the adoption of its rapid microbiological detection technology among pharmaceutical manufacturers.

Oral drug delivery sector tipped for explosive growth

17-Jan-2007 - The rapidly growing market for oral drug delivery is forecast to increase 48 per cent to reach a $52.1 billion in revenues by 2010, with an annual growth rate of...

16-Jan-2007

Protein production in chicken eggs cracked

16-Jan-2007 - Researchers in Scotland have successfully bred five generations of transgenic hens producing therapeutic proteins in the whites of their eggs. This latest news takes the field a step closer to...

Novel extraction method promises ecological low-cost cardiac digoxin production

16-Jan-2007 - Russian researchers have developed a new way of sourcing a widely used cardiovascular drug using an ecologically friendly and water-based extraction method, which could yield three-fold cost savings over conventional...

'Unique website' offers guidance on hazardous waste issues

16-Jan-2007 - A number of small to medium sized firms are unaware of how to use their resources effectively to comply with hazardous waste regulations, opening up an opportunity for online advice...

Acoustic technology 'tops sonication' for tablet QC

16-Jan-2007 - The power of sound waves could aid the pharmaceutical industry in carrying out routine quality control of solid dosage forms, according to the company behind the technology.

Small Eno River Labs thinks big

16-Jan-2007 - The booming pharmaceutical contract research market sees a new player enter the arena as analytical lab Eno River Labs separates into two independent divisions to create a new business that...

15-Jan-2007

RFID chip in plastic wrapping keeps an eye on tampering

15-Jan-2007 - A new radio frequency identification (RFID) chip has been developed by Pliant and IBM that can not only track drug products through the supply chain but also identify when a...

Eli Lilly plans manufacturing ops shake up

15-Jan-2007 - Giant drug manufacturer Eli Lilly last week announced a reshuffle in its global manufacturing operations to reflect the company's focus on its current product portfolio and drug pipeline.

On-line peracetic acid sensor has key CIP use

15-Jan-2007 - UK-based company ProMinent Fluid Controls has launched an on-line sensor targeting the regulation of peracetic acid, a key disinfectant used in the pharmaceutical industry.

Military-certified EP-IR technology for use in quality control

15-Jan-2007 - Aspectric's industrial infrared spectroscopy analyser, recently launched into a market valued at $1.6 billion, has been granted a new US patent.

Cost-cutting plant-based insulin to hit market by 2010

15-Jan-2007 - Canadian firm SemBioSys Genetics last week announced that its proprietary plant-produced insulin has been shown to be indistinguishable from human insulin, opening up a whole new potential source of the...

12-Jan-2007

PerkinElmer continues cellular growth

12-Jan-2007 - PerkinElmer (PE) has continued its growth in the advanced cellular sciences sector, with the completed acquisitions of Euroscreen Products and Evotec Technologies.

11-Jan-2007

Recombinant respiratory antiviral now ready

11-Jan-2007 - Alnylam Pharmaceuticals has started the first human clinical trials to evaluate a new antiviral drug against respiratory synytial virus (RSV) - the major cause of pneumonia and bronchiolitis in children.

Dendrimers encapsulate anticancer drug to improve solubility

11-Jan-2007 - US-based researchers have stepped up anticancer drug usage as dendrimer-encapsulated technology improves camptothecin solubility 10 times and accelerates drug accumulation 16 times in cell culture studies.

TrackWise keeps tabs on Polish pharma quality management

11-Jan-2007 - Drug manufacturers have moved towards centralised data and information management, following a trend to prevent human errors and time-consuming tasks in response to increasing regulatory requirements.

Report shows public think pharma 'puts profits before patients'

11-Jan-2007 - A new report out this week suggests the pharma industry is losing the trust of its key stakeholders. The report, compiled by PricewaterhouseCoopers (PwC), concludes that the growing decline in...

Pharmaphil acquired by US Qualicaps Group

11-Jan-2007 - Qualicaps Group is due to complete the acquisition of Ontario-based firm Pharmaphil by the beginning of next week.

10-Jan-2007

Millipore's NovaSeal simplifies sterile liquid handling

10-Jan-2007 - Millipore has introduced a new disposable product - NovaSeal - that ties in with a shift in the bioprocess manufacturing market to the use of disposable assemblies to shorten production...

SkyePharma aims for $82m with sale of injectable business

10-Jan-2007 - UK-based SkyePharma has found a buyer for its ailing injectable business in a deal that could be worth over $82m (€63m).

Skilled labour shortage hampering RFID adoption

10-Jan-2007 - Radiofrequency identification (RFID) tag adoption will be hampered by a lack of a skilled labour force that is adequately trained to handle this new technology, research reveals.

Cellexus Biosystems 'revolutionises' bioreactor field

10-Jan-2007 - Cellexus has introduced a technology - CellMaker Lite - that satisfies the appetite for disposable bioreactors, grows bacterial and mammalian cells efficiently and cuts production costs.

Pharma industry could feel the heat as US healthcare spending continues to slow

10-Jan-2007 - Although US spending on healthcare rose by 6.9 per cent in 2005, taking it to almost $2 trillion (€1.5 trillion), it's the smallest increase since 1999, down from 7.2 per cent in 2004 and 8.1 per cent in 2003.

Helix picks BioVectra to manufacture new lung cancer bulk drug

10-Jan-2007 - Helix BioPharma and BioVectra have signed a deal for the manufacture of Helix's new lung cancer drug for clinical trials - a move that strengthens the already existing relationship between...

09-Jan-2007

New nanotech anti-cancer drug delivery system introduced

09-Jan-2007 - A new anti-cancer drug delivery system which allows more targeted treatment and helps avoid the unsafe and unpleasant side effects of chemotherapy is due to enter clinical trials in Europe...

MedImmune's new flu formulation gets FDA approval

09-Jan-2007 - MedImmune's latest version of their inhalable flu vaccine, FluMist, has been approved by the US Food and Drug Administration (FDA). The new formulation can now be stored in a refrigerator...

India's drug makers set for business influx

09-Jan-2007 - India's drug manufacturing industry is tipped to grow 10 per cent over the next three years as more pharma firms shift operations there to cut costs, says a research report.

US government dept proposes chemical plant risk assessment

09-Jan-2007 - New US legislation governing the security of chemical production plants will come into force on 4 April 2007, with non-compliers risking daily fines or plant shutdown.

08-Jan-2007

Generics sale on the cards as Merck Serono starts dealing

08-Jan-2007 - Merck KGaA last week confirmed that it is considering selling off its generics division, prompting mass speculation over potential buyers within the industry.

Scientists win patent for nanotech manufacturing process

08-Jan-2007 - US researchers have been awarded a patent for their new manufacturing technology which enables the quick and cheap production of nanoparticles used to formulate and deliver drugs - good news...

Merck & Co increases vaccine manufacturing capacity in Durham

08-Jan-2007 - Drug maker Merck & Co has entered an expansion phase, to boost global manufacturing capacity for vaccines, adding $100 million to its facilities in Durham.

Janssen's Invega approved for schizophrenia

08-Jan-2007 - The US Food and Drug Administration (FDA) has approved Janssen's new drug Invega (paliperidone); the first new prescription drug for the treatment of schizophrenia since 2003.

Melbourn Scientific expands parenteral testing capacity

08-Jan-2007 - Melbourn Scientific has invested in a light obscuration particle counter to size and count particles in liquid samples using light microscopy, to expand the company's capacity in stability testing and...

05-Jan-2007

Applied Biosystems sue Solexa for patent ownership

05-Jan-2007 - Applera's Applied Biosystems group has filed a law suit seeking rights to Solexa's 'sequencing-by-ligation' patents.

Fingerprinting live bacteria

05-Jan-2007 - A mass spectrometric (MS) technique allows rapid detection and identification of bacteria with no need for time consuming pre-treatments.

04-Jan-2007

Sartorius acquires thermoplastics firm Toha Plast

04-Jan-2007 - German technology group Sartorius have acquired all shares in plastics manufacturer Toha Plast.

Gerresheimer adds no1 medical plastics company, Wilden, to its portfolio

04-Jan-2007 - German packaging firm Gerresheimer has acquired Wilden, the European market leader for medical drug-delivery plastic systems, in a move that will show worldwide presence through targeted acquisitions.

New Hep C drug means treatment for the masses

04-Jan-2007 - Philanthropic researchers in the UK have developed a brand new drug for Hepatitis C that dodges restrictive patents held by pharma heavyweights.

Heated liposome drug delivery - effects visualised in vivo using MRI

04-Jan-2007 - US researchers have combined cancer drug-carrying liposomes and heat, which accelerates drug release and delivers 30 times more drug to tumours, as visualised in vivo using magnetic resonance imaging (MRI)

Almac Pharma completes formulation plant expansion

04-Jan-2007 - Solid oral dose product specialist Almac Pharma has announced it has expanded its formulation facilities located at its UK headquarters to provide a wider range of services to pharma and...

03-Jan-2007

Dishman Pharma has its eyes set on biotech CRO companies

03-Jan-2007 - India's Dishman Pharmaceuticals & Chemicals is planning to snap up biotech and nanotech contract research organisation (CRO) companies in Europe and in the US within drug conjugates to expand their...

PerkinElmer snaps up Triton's thermal analysis line

03-Jan-2007 - PerkinElmer has announced its acquisition of a line of Dynamic Mechanical Analysis (DMA) products from UK-based firm Triton Technology in its latest move following a busy year of purchases during 2006.

Temperature-sensing RFID chip could cut shipment losses

03-Jan-2007 - A new radio frequency identification (RFID) tag for temperature-monitoring purposes has been developed for pharmaceutical products during transportation, where fluctuations in temperature can alert the logistics chain of impending disasters.

Portable drug anti-counterfeiting device to hit market

03-Jan-2007 - The pharmaceutical industry's first fully portable drug anti-counterfeiting device will be presented in Baltimore later this month at IFPAC, the International Forum on Process Analytical Chemistry.

Chewable contraceptive for US women

03-Jan-2007 - A US pharmaceutical last month introduced a spearmint-flavoured chewable contraceptive pill as a 'more convenient' option for women 'on-the-go'.

02-Jan-2007

Brady buys Brazilian label maker

02-Jan-2007 - US drug packaging manufacturer Brady has bought a Brazilian label maker in a bid to expand its operations not only in Brazil but throughout Latin America - an area considered...

Actavis expands presence in India

02-Jan-2007 - Icelandic pharmaceutical Actavis has snapped up an Indian manufacturing plant in a move to take advantage of lower manufacturing costs for exports to the US and Europe.

Smaller drug firms risk non-compliance with EU environmental guide

02-Jan-2007 - A number of executives and technical staff at small to medium size pharmaceutical firms are unaware of how to use their resources effectively to comply with new EMEA guidelines, designed...

Eli Lilly confirms UK plant closure

02-Jan-2007 - Giant drug maker Eli Lilly has confirmed that it will be closing its manufacturing facility in Basingstoke, England, resulting in $85m to $95m in restructuring costs for the company.

Pfizer increases Genotropin manufacturing capacity in Sweden

02-Jan-2007 - Pfizer has entered a capacity expansion phase, to meet requirements of global manufacturing of Genotropin (somatropin), a top-selling human growth hormone.

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