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Bioavailability Challenge

Bioavailability Challenge

Drug industry demand for ways of improving drug bioavailability is increasing as industry development pipelines fill with BCS Class II and IV compounds.

in-Pharmatechnologist.com will host "Bioavailability Challenge 2013" a free to attend virtual event where you can discuss the latest scientific breakthroughs with experts and meet with fellow researchers and industry peers.

Sign up for the free, virtual event here .

Oral influenza vaccine one step closer, says Vaxart

22-Oct-2014 - A seasonal flu vaccine taken in the form of an oral solid dose has been found comparable to currently available jabs, according to data presented by developer Vaxart.

Roche's oral octreotide pull-out no risk for Capsugel, says Chiasma

12-Aug-2014 - Chiasma says a scale-up manufacturing agreement with Capsugel will be unaffected despite Roche pulling out of a commercialisation contract for its oral peptide drug octreotide acetate.

New nanotech excipient offers cheaper solubility option say scientists

22-Jul-2014 - Scientists in Sweden have developed a magnesium carbonate-based excipient they claim is a low-cost nanotech alternative to silica for drugmakers struggling to formulate insoluble APIs.

Capsugel: New bioavailability enhancing capacity to fufill non-GMP demand

05-Jun-2014 - Capsugel has installed a commercial-scale dryer in its recently acquired Bend Research R&D facility, citing a rise in demand for non-GMP spray dried dispersion (SDD) services.

'No longer simply a capsule provider' - Capsugel wins oral peptide contract

29-Apr-2014 - Capsugel is no longer a simple capsule provider but a differentiated player in the CDMO industry, the firm says as it wins a scale-up manufacturing contract for Chiasma and Roche’s...

Molecular Profiles' investment makes HME (bio)available for clients

08-Apr-2014 - Molecular Profiles has invested in hot melt extrusion (HME) and nano milling capabilities citing client demand for improving the bioavailablity of drugs.

Feature

Managing excipient supply needs risk guidance, not ‘fear’ says expert

19-Mar-2014 - US pharmaceutical firms ‘fear change’ and need guidance on assessing safe excipient supply to become more like their European counterparts, says a senior IPEC expert.

Bioavailability Breakthrough: Aegis’ enhancement tech works in pill form

19-Mar-2014 - Aegis Therapeutics claims a technology developed to improve the bioavailability of drugs delivered through the nose has a similar solubility enhancement effect in a solid dosage form.

Novo Nordisk buys rights to Caisson’s drug-extending biotech

18-Mar-2014 - Caisson Biotech has licensed its drug-extending technology for injectables to Novo Nordisk.

Targeted drug delivery driving partnerships, says expert

06-Feb-2014 - An increased trend in dealmaking for targeted drug delivery last year will continue to drive partnerships in 2014, according to a pharmaceutical partnering expert.

Aprecia seeks funding ahead of first ZipDose drug launch

16-Dec-2013 - Aprecia Pharmaceuticals has set out to try and raise money to support the commercial launch of the first drug product that uses its ZipDose delivery tech.

Dispatches from AAPS

Spray drying often most applicable in bioavailability challenge, says Bend

12-Nov-2013 - There are multiple ways to make amorphous dispersions in order to enhance bioavailability but spray dry dispersion (SDD) is often the most applicable, Bend Research says.

Capsugel and Bend: 'Marriage made in heaven' as first tech transferred

31-Oct-2013 - The acquisition of Bend Research by Capsugel may be “a marriage made in heaven” for customers, the firms say, as the first drug delivery tech is transferred.

UPDATE - Dispatches from CPhI

Capsugel's purchase of Bend will strengthen partnership, says Dow

28-Oct-2013 - Dow says the acquisition of partner Bend Research is “good news” and will strengthen its developments in solving solubility and bioavailability issues in drug formulation.

dispatches from CPhI

Risk-based supply chain management means more audits for excipient firms

28-Oct-2013 - Regulatory pressure for risk-based supply chain management is increasing excipient suppliers’ audit burden according to the team preparing to launch the 'excipact' certification scheme as an independent association.

Nordic partners Enteris; Licenses bioavailability boosting platform

08-Oct-2013 - Enteris has secured its first partnership to develop metabolic peptides for Nordic Bioscience using an oral delivery platform it says offers unparalleled bioavailability.

Excipients Boost Efficacy in Oral Delivery Platform, says Enteris

06-Aug-2013 - Enteris has acquired an oral drug delivery platform from Unigene Laboratories and says the excipients used can increase solubility and absorption for both peptides and small molecules.

News in brief

Catalent Completes Chinese Softgel Acquisition

30-Jul-2013 - Catalent has completed the purchase of a Chinese softgel firm following regulatory approval.

New Particle Tech May Let Formulators Cut Out Costly Lactose says Pulmatrix

24-Jul-2013 - Dry powder inhaler firms may soon be able to eliminate lactose from formulations if a new high dispersibility particle production platform is successful in trials.

Catalent Combines Core Drug Delivery Services Into New Unit

09-Jul-2013 - Increased challenges in drug delivery have led to Catalent integrating its technologies and services in order to create a new business unit.

DISPATCHES FROM GPCM

'Critical' Compliance for Biologics with Nasal and Long Acting Techs

26-Jun-2013 - Critical Pharmaceuticals says its protein and peptide delivery technologies offer long acting injectables and greater compliance, saving money and easing patient administration.

Capsugel Launches Lipidex Encapsulating Platform from New Dosage Form Unit

17-Jun-2013 - The latest technology platform from Capsugel's four-month old DFS Unit offers greater bioavailabilty and stability in oral dose formulation, says the company.

Metrics Latest Company to Offer Extrusion and Speronization Tech

18-Apr-2013 - Following its acquisition by Mayne Pharma, Metrics says it is to offer proprietary pellet form technology for advanced drug release and to increase bioavailability.

update

Battling Bioavailability? Find Your Solubility Solution at BAC 2013!

18-Mar-2013 - Drug solubility science, technology and solutions will take centre stage at “The Bioavailability Challenge” a free to attend online event in-Pharmatechnologist.com is hosting on Wednesday, March 20. 

BASF says Bend Accord Targets Different Chemistries than Dow deal

25-Feb-2013 - Bend Research has partnered with its second chemistry major in six months, teaming up with BASF to develop bioavailability-boosting excipients.

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