The transdermal and dermal routes are gaining ground in both the prescription and OTC markets. It fits with the trend for improved drug efficacy and patient compliance, and makes self-administration easy and convenient.However higher performing formulations tend to be sensitive,...
Pharmaceutical drug product development can be an expensive and time consuming process. Many challenges are faced by pharmaceutical development companies including developing a scaleable, marketable formulation, ensuring safety and efficacy of the drug product and receiving approval of the drug...
Because the efficacy of the drug depends upon the spray device’s ability to deliver a uniform dose as well as a reproducible droplet size and plume, the delivery system is a critical element for nasal spray performance. Rexam has established...
New studies on the use of Candurin® pearl effect colors in pharmaceutical film coatings were conducted by Merck KGaA of Darmstadt, Germany.According to the results, Candurin® did not exhibit any negative influence on the coating functionality, such as disintegration time...
Kollicoat® MAE shields sensitive APIs from gastric juice, ensuring release in the right place in the body. Find out how various plasticizers interact with MAE in coating formulations by downloading this recently published scientific poster.
The determination of low-molecular-weight aliphatic amines in interfering matrices is a challenging task because the protonated amines are often poorly retained on the column. This problem is met by applying coupled-column matrix elimination.
Technical / white paper
Regulatory authorities (US FDA and the EMEA) impose stringent limits on the amount of microbial contaminates and impurities present during the manufacturing of biological medicines and vaccines.One area of concern is that the cell substrates used in the production of...
Technical / white paper
The new edition provides readers with an even better understanding of solid dispersions and the hot-melt extrusion process. It offers an overview of BASF’s polymers, more real-world application data and factors to consider in the formulation process
Available for global markets and all therapeutic areas, Safe’n’Sound® devices by Rexam provide healthcare professionals and patients with a full protection from needle sticks to prevent accidental contamination
Together, TruScan RM and microPHAZIR RX let you identify 90% of pharmaceutical compounds in seconds. With both instruments you’ll quickly and effectively identify any combination of materials in your manufacturing facility, from receipt to release.Visit us at CPhI in Madrid...
Collaborative partnering between Contract Development and Manufacturing Organizations (CDMO) and the drug product submission applicants is becoming increasingly important with the emphasis on product design by regulatory agencies.The CDMO can provide the appropriate resources to build the scientific knowledge base...
Capsugel is a global leader in innovative dosage solutions for Healthcare. Visit Capsugel at ICSE – Oct 9-11 and AAPS Oct 14-18 .The experience at Capsugel’s booth will feature proprietary market research and the latest capsule technology
Radio Ion ChromatographyPositron emission tomography (PET) is one of the most powerful noninvasive diagnostic tools for tracing organ functioning. Quality control of the short-lived PET-radiopharmaceuticals is challenging, not least because of the tough time limits, the radiation issue and the near nanomole radiotracer...
Maximize your drug active and overall formulation stability with high purity PEG 400. Croda’s Super Refined® PEG 400 has demonstrated it improves API stability as well as reduces gelatin cross-linking.
Designed especially for solid solutions, Soluplus significantly boosts the solubility and bioavailability of poorly soluble APIs. Find out how Soluplus performed in an in-vivo test – download a recently published scientific poster.
On-Demand Supplier Webinar
iCELLis™ is a scalable line of bioreactors combining the advantages of single-use technologies with the benefits of a fixed-bed system. By providing up to 500m² – equivalent to 3000 Roller Bottles - iCELLis offers a simpler alternative for process efficiency.
Molecules reaching the market in the recent years present an ever-growing complexity and purity criteria are more stringent than ever. The right combination of smart synthesis and advanced purification is necessary to meet the demand in a cost-effective and time-efficient...
On-Demand Supplier Webinar
This webinar will discuss development of design spaces for lyophilized pharmaceutical products in the context of the Quality by Design regulatory paradigm. Steven Nail, PhD, principal scientist at Baxter’s Lyophilization Center of Excellence with extensive expertise in the field, presents...
API bioavailability can be optimized through enhancing the stability of your API itself and by improving overall oxidative stability of your formulation. Croda’s Super Refined Oils have demonstrated these benefits. Fill the form for more information.
Amcor MediCan has been designed to meet the most stringent packaging requirements of the healthcare industry. This product combines the strong barrier of aluminum against light, moisture and oxygen with the high stability of containers, providing a high product protection...