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Library > White / Technical Paper

How to Approach Identification of Anomalous Peaks

Published: 22-Feb-2012 | Format: PDF file | Document type: White / Technical Paper

The sudden appearance of an unknown peak during an HPLC analysis of a pharmaceutical product can be a critical finding causing delays and requiring considerable resources to resolve.

The unknown peak can be caused by many things ranging from simple sample prepa­ration contamination, all the way to unexpected degradation/stability properties of the product.

It is essential that a rapid and effective investigation take place to quickly determine the identity of the anomalous peak and determine the root cause of its presence in the product.

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