Choosing the Right Dimension of Purity
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22-Dec-2004
New drug class treats neurodegeneration
22-Dec-2004 - The first study to confirm the potential of a new class of drug for neurodegenerative disorders such as Alzheimer's could herald a breakthrough in drug treatment for a disease that...
Electrochemical systems boost MS
22-Dec-2004 - ESA has successfully employed its electrochemical (EC) systems in conjunction with a mass spectrometer to greatly expand the number and types of molecules for analysis.
Spotlight falls on naproxen
22-Dec-2004 - The ongoing controversy concerning certain drugs and a link to heart trouble gained further momentum after the Food and Drug Administration (FDA) issued a warning for the pain reliever naproxen...
Pharma production news in brief
22-Dec-2004 - In-PharmaTechnologist.com's periodic round-up of developments in the pharmaceutical manufacturing sector sees Schering-Plough expanding in Japan and plant news from Germany, Mexico and Vietnam.
CMOs go niche in tough climate
22-Dec-2004 - At the CPhI meeting this year, many contract manufacturing organisations (CMOs) trumpeted their new investments in capacity, despite the prevailing wisdom that the pharmaceutical sector is over-served at present.
Roller improves cell culture yields
22-Dec-2004 - Cell culture equipment company Integra Biosciences has launched a new roller system designed to improve the cultivation of adherent and suspension cells.
21-Dec-2004
Pall completes protein purification acquisition
21-Dec-2004 - Separation and filtration giant Pall has completed its $32 million acquisition of BioSepra, a division specialising in protein purification technologies, from Ciphergen.
Inyx to buy Sanofi-Aventis firm
21-Dec-2004 - US drug delivery company Inyx has signed a definitive agreement to acquire Aventis Pharmaceuticals Puerto Rico, part of the French Sanofi-Aventis group.
COMPASS points to best blisters
21-Dec-2004 - Tekni-Films, part of the Tekni-Plex group, has introduced a new blister package modeling system to support pharmaceutical manufacturers in the development of packaging for oral solid dosage forms.
OptiNose takes nasal delivery to a higher level
21-Dec-2004 - Norwegian drug delivery specialist OptiNose has raised €4.5 million in a new financing that will support the development of its nasal delivery system, designed to hike efficiency over current devices.
Tax savings from smart supply chain management
21-Dec-2004 - Companies in the European life sciences industry could save significant sums of money, up to 5 per cent of turnover in some cases, by considering tax implications in their supply...
Alltracel buys oral care company
21-Dec-2004 - Irish biopharma firm Alltracel Pharmaceuticals has reinforced its position in the dissolvable film market with a reverse takeover of London firm Westone Products.
20-Dec-2004
Pfizer: Celebrex poses heart risk
20-Dec-2004 - The safety of cox-2 inhibitors was plunged into further uncertainty after Pfizer released details of trials that found an increased risk of heart problems with patients taking its painkiller Celebrex....
New class of virus changes shape during infection
20-Dec-2004 - A new approach to prevent infection of West Nile and dengue fever may be on the horizon after a US team identified interactions involving the alfalfa mosaic virus (AMV). The...
Wyeth seeks approval of new class antibiotic
20-Dec-2004 - Wyeth Pharmaceuticals has announced the submission of a global registration dossier for its investigational antibiotic Tygacil (tigecycline), a new class of treatment for intra-abdominal and skin infections.
Flamel starts trials of Medusa interferon
20-Dec-2004 - France's Flamel Technologies has enrolled the first patient in a clinical trial of its Medusa drug delivery technology, used to develop sustained-release formulations of therapeutic proteins.
New ligands from Degussa
20-Dec-2004 - Degussa Homogeneous Catalysts, an internal start-up company operating as part of the Degussa chemical group, introduced a new family of ligands at the CPhI meeting.
Reduced additive film from AstraZeneca
20-Dec-2004 - Researchers at AstraZeneca in Sweden have been granted a US patent on a new film coating for tablets that can be carried out in water-based conditions, doing away with the...
Esco upgrades class II biosafety cabinet
20-Dec-2004 - This month will see the launch of the second generation of Esco's Airstream Class II (AC2) biosafety cabinet, used for potentially hazardous applications such as cell culture, virus propagation and...
Cottoner doubles packing speed
20-Dec-2004 - NJM/CLI has launched a second product in its range of cottoner systems for the pharmaceutical and nutraceuticals packaging industries.
16-Dec-2004
Flarer launches gum for drug delivery
16-Dec-2004 - Flarer, a Swiss company specialising in methods of drug delivery, has developed a new chewing gum production technology that extends the range of active pharmaceutical ingredients (API) that can be...
Teva turns to Codexis for process improvement
16-Dec-2004 - Codexis has signed a research collaboration agreement with generics company Teva Pharmaceutical Industries to develop improved processes for the manufacturing of a currently marketed fermented pharmaceutical product.
Cerestar launches Sorbidex formulation
16-Dec-2004 - Cerestar has responded to the rising demand for starch-based excipients by extending its range of Sorbitol products, two non-animal and non-synthetic based formulations that offers a carrier platform for active...
Merck raises staff cuts to 5,100
16-Dec-2004 - Merck & Co, still reeling from the impact of pulling its painkiller Vioxx (rofecoxib) from the market, is to slash its staff by 5,100 positions in a bid to save...
Research group takes aim at bad packaging
16-Dec-2004 - Researchers at the University of Derby in the UK are appealing for industrial partners to join their research programme into tackling problems associated with misleading medicine labels, difficult drug names...
15-Dec-2004
EPO revokes Applera's PCR patent
15-Dec-2004 - Applera suffered a setback to its European sector after the European Patent Office revoked its patent covering real-time PCR thermal cycler technology.
New fine chemicals group formed in Europe
15-Dec-2004 - The European Chemical Industry Council (CEFIC) has set up a new umbrella group to represent the fine chemicals industry and provide forum to tackle the volatile environment facing the sector.
Making DNA without bacteria
15-Dec-2004 - CytoGenix has filed a patent application for a technology that it claims could dramatically increase the efficiency of DNA production.
Clariant expands into controlled substances
15-Dec-2004 - Clariant's pharmaceutical fine chemicals business announced a series of upgrades to its manufacturing facilities around the world, headed by a new push into contract manufacture of controlled substances.
Artificial tongue helps medicine go down
15-Dec-2004 - Japan's Insent has developed an artificial tongue - said to be the first of its kind - that can be used to analyse the taste profiles of pharmaceuticals, foods and...
14-Dec-2004
Injector adds flexibility to gas chromatography
14-Dec-2004 - Shimadzu Scientific Instruments has launched a new high-throughput gas chromatograph injection system that is designed to allow GCs to easily switch from one task to another.
NPcaps makes its European debut
14-Dec-2004 - A non-animal alternative to gelatin capsules made its European entry as Capsugel used the CpHi show to launch the latest addition to its range of two-piece capsules. The product claims...
Cardinal slashes jobs in restructuring
14-Dec-2004 - Drug distribution and pharmaceutical technology firm Cardinal Health has added detail to its previously announced restructuring initiative with the news that it plans to cut 4,200 jobs and close 25...
China to review catechol imports
14-Dec-2004 - The Ministry of Commerce in China has that it plans to review the five-year programme of anti-dumping duties it set on catechol imports from the European Union.
The end of high-throughput crystallisation?
14-Dec-2004 - UK company Accentus has developed a technology that promises to halve the cost of carrying out high-throughput crystallography, used in polymorph screening and salt selection as part of the process...
13-Dec-2004
People on the move
13-Dec-2004 - Busy times for personnel in the pharmaceutical technology sector, with a series of new appointments at the senior level in ingredients, separation and drug delivery companies.
Cutting the price of malaria cure
13-Dec-2004 - A non-profit pharmaceutical company, the Institute for OneWorld Health, has been awarded a $42.6 million (€32.1m)grant from the Bill & Melinda Gates Foundation to find a new way of producing...
RNAi offers fresh approach to drug discovery
13-Dec-2004 - With the advent of ribonucleic acid interference (RNAi) offering a radical approach to drug discovery, the emphasis is now placed on finding the most efficient means to deliver or transfect...
Hovione head seeks level playing field for API players
13-Dec-2004 - European contract manufacturers of active pharmaceutical ingredients (APIs) are operating under a system of regulatory double standards that is destroying their ability to compete in the marketplace.
BASF extends Kollicoat IR range
13-Dec-2004 - German chemicals group BASF has launched two new pharmaceutical film-coating products, cementing its position in a market estimated to be worth about €200 million and growing at 5 to 6...
Intranasal delivery of insulin shows promise
13-Dec-2004 - Bentley Pharmaceuticals has successfully delivered insulin to type 1 diabetics using its novel intranasal formulation, throwing its hat into the ring of companies seeking to replace insulin injections with more...
10-Dec-2004
Capsules better delivery form for tea benefits than beverage
10-Dec-2004 - Tea polyphenols are more bioavailable when delivered as encapsulated green tea extract than when taken as a traditional beverage, according to a small trial.
Lonza expands presence in China
10-Dec-2004 - Lonza has revealed a plan to further strengthen its presence in China with the construction of a new research and development centre in Guangzhou.
Long-acting morphine launched in US
10-Dec-2004 - US drug delivery company Endo Pharmaceuticals has launched a novel formulation of the opioid analgesic morphine sulphate that can provide 48 hours of pain relief in a single dose.
Merck boosts service to support fine chemicals
10-Dec-2004 - The challenging environment for companies supplying chemicals into the pharmaceutical sector, with a relentless increase in competition, has prompted German company Merck KGaA to start a new service aimed at...
Malarial drug target revealed
10-Dec-2004 - A potential new drug target for malaria was revealed this week after scientists discovered the structure and function of the malaria parasite, Plasmodium falciparum, for the first time. The findings...
Antibiotic target signals pneumonia end
10-Dec-2004 - Scientists have found a molecular weakness in the organism that causes pneumonia, providing a target for the development of a new class of antibiotics that could eventually eradicate the disease.
Quadrant launches colour range for acetal stockshapes
10-Dec-2004 - Quadrant Engineering Plastics Products (EPP) has launched a range of standard colours for extruded acetal stockshapes in response to increasing market demand for products that enable and enhance colour identity.
08-Dec-2004
One-pot process for toxic APIs
08-Dec-2004 - Manufacturers of active pharmaceutical ingredients (APIs) can reduce the risk of exposure to highly toxic active ingredients using a new process system developed by Collette, part of Niro Pharma Systems.
Groninger invests in CAD technology
08-Dec-2004 - German packaging machinery company Groninger & Co has bought a new computer-aided design software package that it says will enable it to meet the demands of its customers more closely.
Chiesi buys dose counter for Modulite inhaler
08-Dec-2004 - Italy's Chiesi Farmaceutici has signed a deal with Ontario, Canada-headquartered Trudell Medical International for the latter's MDI actuation indicator, designed to make it easuer for asthmatics to see when their...
CMO sector will see more rationalisation
08-Dec-2004 - At the Conference on Pharmaceutical Ingredients (CPhI) opened its doors yesterday, In-PharmaTechnologist.com spoke with Nick Hyde, global business director at leading contract manufacturer Dowpharma, to hear his views on the...
07-Dec-2004
NMR ushers in new check weighing era
07-Dec-2004 - A new weighing system developed by BOC Edwards Pharmaceutical systems can be used in a pharmaceutical filling line but does not come into contact with the weighed materials.
Novo adds antibodies to Morphotek deal
07-Dec-2004 - Danish drug company Novo Nordisk has licensed rights to an antibody generation technology developed by US company Morphotek that simplifies the process of scaling up to manufacturing levels.
Smart drug pack doing CRO rounds
07-Dec-2004 - US packaging giant MeadWestvaco has made progress in its collaboration with Cypak, a Swedish company specialising in the development of 'smart' packaging.
European pharma news in brief
07-Dec-2004 - In-Pharmatechnologist presents a round-up of pharmaceutical sector news from around the European continent.
06-Dec-2004
CPhI 2005 will add machinery expo
06-Dec-2004 - In-Pharmatechnologist.com will be reporting this week from the Conference on Pharmaceutical Ingredients (CPhI) and in Brussels, Belgium, now in its 15th year and widely regarded as the premier event for...
Novartis, Emisphere alliance expanded into osteoporosis
06-Dec-2004 - Novartis has paid a US drug delivery company $10 million for an option to an oral formulation of an injectable drug used to treat osteoporosis that is currently the subject...
Bayer to slash 560 jobs, with HQ hard hit
06-Dec-2004 - German drugmaker Bayer last week put an end to speculation that it is planning swingeing job cuts by conforming that it is planning to axe 560 positions in Germany and...
People on the move
06-Dec-2004 - In-Pharmatechnologist's periodic round up of personnel moves in the industry includes a crop of new chief executives and senior managers across the pharmachem, drug development and manufacturing sectors.
05-Dec-2004
Sanofi Aventis to spin off anti-infective unit
05-Dec-2004 - A new anti-infectives company, spun out of the Sanofi-Aventis group, has received €40 million in financing from an international group of leading life science investors led by Atlas Venture and...
Animal extremism: Queen announces law changes
05-Dec-2004 - New laws to stop increasingly violent animal extremists from harassing scientists involved in medical experiments have received the seal of approval by the Association of the British Pharmaceutical Industry (ABPI).
Wound healing drug reduces cardiac damage
05-Dec-2004 - A naturally occurring protein, which promotes the ability to repair heart muscle after a myocardial infarction, significantly reducing cardiac damage, may have drug applications as a wound healing treatment for...
03-Dec-2004
Advanced thermal cycling becomes affordable
03-Dec-2004 - The first thermal cycler to start at under £1000 (€1400) is set to start a price war for this product, which has proved invaluable for amplification of nucleic acids.
SGX and CFFT map Cystic Fibrosis protein
03-Dec-2004 - Structural GenomiX (SGX) and the Cystic Fibrosis Foundation, have made a breakthrough in Cystic Fibrosis (CF) research by identifying the three-dimensional crystal structure of a protein that has been implicated...
J&J to stop topiramate obesity trials
03-Dec-2004 - Pharmaceutical giants Johnson and Johnson announced today it is to discontinue its current clinical development program for its controlled release formulation of topiramate in obesity after studies revealed the formulation...
02-Dec-2004
Niro unveils lab-based processing system
02-Dec-2004 - Niro Pharma Systems recently launched a new laboratory fluid bed - the STREA-1 - for the processing of fine powders, pellets, granules, crystals, tablets and organic solvents. The system, developed...
New generation PEG launched
02-Dec-2004 - UK company Warwick Effect Polymers has launched a new type of polyethylene glycol (PEG) to improve the half-life of biologic drugs in the body.
Biomanufacturing at overcapacity through to 2011
02-Dec-2004 - The predicted deficit in manufacturing capacity for biologic drugs that has been tipped to impede the development of the market has not materialised, with capacity exceeding demand, according to new...
AstraZeneca starts work on Egyptian facility
02-Dec-2004 - AstraZeneca has started construction a €30 million tablet manufacturing plant in Egypt that could form a springboard for an expansion into emerging markets.
International production news round-up
02-Dec-2004 - In-Pharmatechnologist.com's periodic round-up of pharma production developments from around the world sees Cognis mulling the sale of process chemicals, Perrigo buying a generics and API manufacturer and two new contract...
01-Dec-2004
Competitiveness Council mulls REACH proposal
01-Dec-2004 - A joint proposal by the UK and Hungarian governments that would allow chemical companies to share the cost of testing to comply with the new REACH legislation has received the...
Sumitomo, Dainippon marriage adds to Japanese M&A
01-Dec-2004 - Japanese drugmakers Dainippon Pharmaceutical and Sumitomo Pharmaceuticals are to merge in an attempt to increase their standing in international markets and fend off competition at home.
H&R Wasag triples pharmachem sales
01-Dec-2004 - German chemical company H&R Wasag was hit once again by the tough market environment in the third quarter of the year, but offset some of the impact by buying up...
Inyx study validates new aerosol technology
01-Dec-2004 - Inhaled drug delivery company Inyx has reported positive results from a two-year stability study of a non-ozone-depleting, hydrofluoroalkane (HFA) propelled salbutamol metered dose inhaler (MDI) for treating asthma and other...
Process chemistry meeting taking shape
01-Dec-2004 - The American Chemical Society has announced that its fourth annual ProSpectives Conference on process chemistry will be held 6-9 February in Miami.
Organon investigates non-hormonal menopausal therapy
01-Dec-2004 - Dutch drug company, Organon, has initiated further studies to develop a specific class of non-hormonal drugs to treat the hot flushes associated with menopause. The new drug, currently in development,...
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