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30-Nov-2004
BioPartners files for 'biosimilar' hGH
30-Nov-2004 - Switzerland-based BioPartners has submitted a second Marketing Authorisation Application in Europe for a generic copy of a biologic drug under the recently agreed European Union framework for so-called 'biosimilar' drugs.
Ultrapure water unit from Christ Water
30-Nov-2004 - Germany's Christ Water Technology has developed a ready-to-connect water filtration plant that is specifically designed for use in the pharmaceutical, chemical and cosmetics industries.
Pharming raises €6m for new projects
30-Nov-2004 - Pharming of the Netherlands, which is pioneering the use of transgenic animals for the production of biologics, has raised €6 million from a placing of shares and will use the...
NJP buys into flexible pharma packaging
30-Nov-2004 - In the US, New Jersey Packaging has acquired Altwood Roll Label, which supplies flexible packaging, inserts and labels to the pharmaceutical and healthcare sector.
29-Nov-2004
Flint announces packaging ink price increase
29-Nov-2004 - Flint Ink North America has announced a price increase for packaging ink products ranging from 5 to 7 per cent depending on ink type. The increase, effective 1 December 2004,...
Gene therapy shows promise in Parkinson's disease
29-Nov-2004 - Research that could eventually lead to gene therapy treatment options for patients with Parkinson's disease has been published this week, which could bring hope to more than 1 million Americans...
Long chain amyloid a drug target?
29-Nov-2004 - Scientists have identified a new, longer species of the amyloid b-peptide that has the potential to be a new target for the treatment of Alzheimer's disease The discovery serves as...
Avecia sells off nitroglycerin business
29-Nov-2004 - Manchester, UK-based Avecia has sold off its Special Drug Mixtures subsidiary to Copperhead Chemical of the US.
Merck exits another French production site
29-Nov-2004 - German chemical and pharmaceutical company Merck KGaA has sold off a manufacturing facility in France in a move aimed at consolidating its global production infrastructure.
Packaging film prices on the rise
29-Nov-2004 - The UK Packaging and Industrial Films Association (PIFA) is warning buyers of plastic film products to expect further price increases as producers and converters are forced to look for recovery...
Slow growth for Euro API suppliers forecast
29-Nov-2004 - Overcapacity remains the main issue affecting the European market for active pharmaceutical ingredients, with lack of capability differentiation and competition from low-cost manufacturers also holding back growth in the sector.
Peptide synthesis made simple with new enzyme
29-Nov-2004 - Japan's Ajinomoto has developed a revolutionary enzymatic method to manufacture peptides that could dramatically cut the cost of producing this growing class of therapeutic agents.
26-Nov-2004
Artificial liver an alternative to toxicity testing
26-Nov-2004 - Bioengineers at the University of Oxford have developed a solution to the problem of toxicity testing for new drugs, which can prove to be ineffective or at worst dangerous to...
25-Nov-2004
BASF trims down at Ludwigshafen
25-Nov-2004 - German chemical giant BASF is to shed about 3,600 jobs at its main Ludwigshafen plant over the next three years as part of efforts ensure the site's competitiveness.
Consortium AIMs to cut MAb production costs
25-Nov-2004 - The European Commission has launched an €11.4 million project to identify ways of improving the production of biologic drugs and cutting the cost of treatment.
Wyatt Technology buys Dynapro manufacturer
25-Nov-2004 - Wyatt Technology, a specialist in macromolecular characterisation instrumentation and software, has completed the acquisition of Proterion Corp, a US firm making dynamic light scattering instruments.
International production news round-up
25-Nov-2004 - In-Pharmatechnologist.com's periodic round-up of pharma production developments from around the world sees a Spanish contract manufacturer adding capacity, a new GMP plant in China, upgrades to facilities in Canada and...
New drug extends multiple sclerosis options
25-Nov-2004 - The first in a completely new class of drug for multiple sclerosis has been approved in the US, opening up a new avenue of treatment for sufferers of the debilitating...
UK academic turns to AFRICA for process development
25-Nov-2004 - After a successful trial period, Syrris has supplied one of its recently-launched AFRICA microreactor systems to Professor Steven Ley at the Department of Chemistry at the University of Cambridge, UK....
24-Nov-2004
Cambridge film assessed by BioProgress
24-Nov-2004 - BioProgress has signed an agreement with Cambridge University Technical Services Ltd giving it an exclusive eight month option to evaluate new film technology developed at the UK university, writes Phil...
Patheon buys Puerto Rican rival
24-Nov-2004 - Contract pharmaceutical manufacturer Patheon is to buy Puerto Rican rival Mova Pharmaceuticals in a transaction that could be valued as high as $350 million in cash, stock and assumed debt.
Charles River to back genOway's animal models
24-Nov-2004 - Charles River Laboratories of the US and France's genOway have formed a collaboration to market genetically modified research models to research customers in Europe.
New client for BioPharm-Alliance
24-Nov-2004 - Parexel and Sartorius have been awarded a contract to supply, validate and help operate a biologic manufacturing facility in South Korea, said to be the first of its kind in...
DSM buys stake in Chinese pharma group
24-Nov-2004 - Dutch chemicals and ingredients company DSM is to purchase a stake in North China Pharmaceutical Group in a move that boosts its presence in the country, writes Phil Taylor.
Automated HT crystallography transforms drug discovery
24-Nov-2004 - High throughput protein (HTP) crystallography is set to undergo key technical developments in which the development of automation in protein expression, protein engineering and crystallisation will provide the accurate screening...
Chr Hansen planning ingredients sale
24-Nov-2004 - Denmark's Chr Hansen is considering breaking up into two separate entities, one focused on food and pharmaceutical ingredients and the other a pharmaceutical pure-play making allergy vaccines and asthma treatments,...
23-Nov-2004
Avery Dennison gears up for EU fine
23-Nov-2004 - Avery Dennison, one of the world's largest suppliers of pressure sensitive adhesive labels, is expecting to be fined by the European Commission for what it describes as 'instances of improper...
Freeman launches new module for FT4 rheometer
23-Nov-2004 - Freeman Technology has launched the first in its range of 'plug and play' accessories that will automate powder flow testing on the company's FT4 Powder Rheometer, after adding in a...
Medtronic insulin pump will use NovoLog cartridges
23-Nov-2004 - Danish pharmaceutical company Novo Nordisk has inked a deal with a US medical device manufacturer that will extend the use of insulin cartridges from autoinjectors to external insulin pumps.
RFID project extended in Germany
23-Nov-2004 - As the pharmaceutical industry gears up to use radiofrequency identification for supply chain management, medical suppliers in Germany have already adopted the technology to track blood products and no plan...
Transport gets $27m in VC funding for drug delivery
23-Nov-2004 - US drug delivery company Transport Pharmaceuticals has raised $27 million in a financing round.
22-Nov-2004
Roche consumer health sale cleared by EU
22-Nov-2004 - Bayer's acquisition of the Roche consumer health business, a major player in the vitamin supplements market, has been approved by the European antitrust authorities, giving way to the creation of...
Automated cell culture to revolutionise drug discovery
22-Nov-2004 - Applying automation to tissue culture techniques can improve the development, maintenance and expansion of mammalian cells, increasing the efficiency of drug discovery efforts, reports Wai Lang Chu.
France outlines plans to kickstart biotech
22-Nov-2004 - France's drug industry has started filling in the detail of its strategic plan to boost the standing of the biotechnology sector, first unveiled at the end of last month. At...
Mocon automates methylene blue test
22-Nov-2004 - Mocon has introduced a new system that automates the classic methylene blue dye test (MDT) for assessing the integrity of blister packs, as well as providing comprehensive documentation for auditing.
Lanxess spin-off cleared by Bayer shareholders
22-Nov-2004 - Bayer stockholders have cleared the way for the spin-off of chemical unit Lanxess, with voters holding 99.66 per cent of the company's capital stock supporting the split.
Fatal attraction: magnets tested in cancer treatment
22-Nov-2004 - UCB subsidiary Celltech has joined forces with the University of Durham and another UK-based company to develop an unusual approach to treating cancer using magnetic fields.
Ultrafast laser could improve reaction control
22-Nov-2004 - A team of researchers in the US has developed a new way of using laser spectroscopy to detect the energy level of atoms in a gas, which could have applications...
19-Nov-2004
FMC Bio reports progress with tablet coating
19-Nov-2004 - FMC BioPolymer is making progress in its collaboration with BioProgress and Harro Hoefliger on a machine to produce its recently-acquired NROBE tablet coating technology.
Chemi invests in PS production
19-Nov-2004 - Italian firm Chemi is moving production of the nutraceutical ingredient phosphatidylserine to its pharmaceutical actives plant in Brazil, allowing it to increase capacity and become more competitive on price.
Nanotechnology to benefit drug discovery
19-Nov-2004 - Nanotechnology for molecular targeting and drug delivery is set to become a trillion-dollar industry with the drug sector's economic and technological leadership key to the growth of the technology.
Top 2 pharma firms turn to RFID
19-Nov-2004 - The top two pharmaceutical companies have signaled their commitment to the adoption of radiofrequency identification (RFID) and electronic product code (EPC) technologies in the battle against counterfeit drugs.
Multi-purpose packaging quality tester launched
19-Nov-2004 - A new system that offers both pressure loss measurement and packaging seal strength has been launched.
In brief: pharma production around the world
19-Nov-2004 - In-Pharmatechnologist.com's periodic round-up of manufacturing developments from around the world sees Fujisawa expanding in Ireland, Solvay partnering in Russia, Vietnam's machinery firms undercutting competitors and a US plant purchase.
Chr Hansen profit dips on cost increases
19-Nov-2004 - The ingredients division of Danish company Chr Hansen pulled in a DKK 369 million (€49m) profit for the fiscal year on sales of DKK 3.4 billion (€460m), a slight dip...
Protein kinase target emerges in Parkinson's
19-Nov-2004 - German, US and Canadian researchers have discovered a gene and six mutations that cause symptoms associated with Parkinson's disease and other neurodegenerative disorders.
Spray on hormonal therapy from VIVUS
19-Nov-2004 - US drug company VIVUS as been granted a US patent relating to a new drug delivery technology that makes it possible to spray drugs onto the skin and have them...
18-Nov-2004
Sherwood links with laser firm for coding tech
18-Nov-2004 - Sherwood Technology has formed a collaboration with Domino - the largest international producer of CO2 laser-marking systems - to expand the distribution of its recently-launched DataLase coding system.
Lonza expands biologics manufacturing capacity
18-Nov-2004 - Lonza has commissioned a new current Good Manufacturing Practice-compliant facility for the production of microbially derived biopharmaceuticals at its largest worldwide production centre in Visp, Switzerland.
Schering, BMS cut manufacturing staff
18-Nov-2004 - Germany drugmaker Schering is planning to reduce its headcount by 1,250 with most of the cuts coming in production. The company is blaming increased cost pressures due to European and...
OTC market sees another oral strip entrant
18-Nov-2004 - US drug delivery company Zengen has announced that its consumer health subsidiary InnoZen has launched another over-the-counter (OTC) pharmaceutical in oral film strip format, a delivery vehicle that is being...
Drug labels cause problems for sight impaired
18-Nov-2004 - The pharmaceutical industry is doing little to help people with impaired or partial sight get information from drug labels, according to a new study which found a font change could...
17-Nov-2004
Alnylam overcomes delivery problem with RNAi
17-Nov-2004 - In the race to develop therapeutics based on RNA interference, Alnylam Pharmaceuticals has claimed a first with the publication of a study showing in vivo RNAi-mediated gene silencing in mammals...
16-Nov-2004
Emisphere makes progress with oral insulin
16-Nov-2004 - US drug delivery company Emisphere Technologies reported promising results last week with an oral formulation of insulin that could do away with the need for injections in people with diabetes.
Millipore unveils new Steritest pump
16-Nov-2004 - Millipore has launched a new pump designed to improve sterility testing of materials in aseptic manufacturing. The Steritest Equinox pump is a liquid transfer pump for sterility testing in laminar...
EMBL, Abnova partner on MAb production
16-Nov-2004 - The European Molecular Biology Laboratory (EMBL) has joined forces with a Taiwanese company Abnova, to develop a high-throughput system for making monoclonal antibodies (MAbs).
Zambon exits inhaler pact
16-Nov-2004 - The march towards multidrug therapy of asthma has caused Italy's Zambon to pull out of a research project aimed at developing new inhaler formulations of the steroid budesonide and bronchodilator...
SemBioSys patents vaccine production tech
16-Nov-2004 - Canada's SemBioSys Genetics has been granted a US patent on a vaccine production system that uses genetically modified seeds as biological factories of vaccine antigens.
15-Nov-2004
Project seeks membrane protein breakthrough
15-Nov-2004 - A pioneering research project could pave the way for more effective drug treatments for diseases including cancer, parasitic, bacterial and viral diseases by visualising, in detail, membrane proteins that have...
COX-2 inhibitor debate rumbles on as Merck accused of delay
15-Nov-2004 - A new study suggests that there are important differences between Merck & Co's Vioxx (rofecoxib) and other COX-2 inhibitors and that this may account for variations in cardiovascular safety within...
Plastic packaging on the rise in healthcare
15-Nov-2004 - Plastics are featuring more often in the packaging of healthcare products, including pharmaceuticals, and this will drive a 28 per cent increase in the volume of plastic resins used between...
Pfizer completes inhaler company acquisition
15-Nov-2004 - Drug giant Pfizer has completed its purchase of UK-based drug delivery company Meridica in a move that it says will bolster its activities in allergy and respiratory medicine.
Latest Borculo Domo deal targets Scandinavia
15-Nov-2004 - Lactose specialist Borculo Domo has teamed up with Univar to ramp up its presence in the Scandinavian pharmaceutical market, part of a concerted effort to improve its standing internationally.
Molecular technique kills drug resistance bacteria
15-Nov-2004 - A new approach to outwit resistance to antibiotics has been discovered by a team of researchers who hope to apply this knowledge to form new strategies and targets to combat...
'Positive' showing for pharma at BASF
15-Nov-2004 - Lower sales prices for vitamin C and the feed ingredient lysine ate into fine chemicals revenue at BASF during the third quarter, contributing to a 5 per cent decline in...
UK to hike transparency in drug regulation
15-Nov-2004 - A number of measures to help make the UK Medicines and Healthcare Products Regulatory Authority (MHRA) and the pharmaceutical industry operate more openly and transparently were announced late last week...
12-Nov-2004
Oxoid test improves on MRSA detection time
12-Nov-2004 - A laboratory test that is able to detect methicillin resistant Staphylococcus aureus (MRSA) a day earlier then traditional antimicrobial susceptibility testing (AST) gives fresh impetus to treatment and infection control...
10-Nov-2004
BioProgress taps CMO for production space
10-Nov-2004 - BioProgress, which makes cellulose based XGEL films for coating tablets and capsules, has signed an agreement with a contract manufacturing organisation to accelerate the installation of its own film manufacturing...
Wyeth selects drug targets in osteoporosis deal
10-Nov-2004 - Galapagos Genomics are set to receive additional milestone payments of up to $40 million (€30.9 million) after its osteoporosis discovery program with Wyeth Pharmaceuticals resulted in the US drug gaints...
Waiver sought on compulsory licenses in India
10-Nov-2004 - With just a few weeks to go before the introduction of India's new patent regime - which will increase protection to include product as well as process patents - a...
First manufacturing deal for siRNA treatment reached
10-Nov-2004 - The first ever-manufacturing agreement for a drug based on small interfering RNA emphasises the potential of this pioneering therapeutic approach, which could be a fertile stamping ground for contract manufacturers.
Dessicant sachet dispensers cut costs
10-Nov-2004 - Active-Pak Automation claims that companies installing its dessicant sachet dispensing systems can achieve cost savings of up to 40 per cent compared to systems based on canisters, offsetting the capital...
Novel solid phase boosts oligo yields and cuts costs
10-Nov-2004 - Nitto Denko and antisense specialist Isis Pharmaceuticals have jointly developed a new solid support for the manufacture of oligonucleotides that promises to reduce the high manufacturing costs for this type...
09-Nov-2004
S&S buy helps Whatman close on separation leaders
09-Nov-2004 - Setting aside the acrimony of a patent dispute, UK separations company Whatman is to buy German rival Schleicher & Schuell for €50.2 million, allowing it to narrow the gap between...
Status quo keeps US pharma happy
09-Nov-2004 - The news that US President George Bush will be residing at the White House for a further four years has been greeted with some measure of relief by the pharmaceutical...
Advanced terpolymers developed for better packaging
09-Nov-2004 - Borealis has developed new advanced Borseal terpolymers to improve biaxially oriented polypropylene (BOPP), a raw material used in clear film packaging.
Tagatose gets first pharma customer
09-Nov-2004 - US company Spherix has made the first sale of its Naturlose sweetener to a company in the pharmaceutical sector, since the products was cleared for this application last December.
Novo Nordisk expands production in China
09-Nov-2004 - Danish pharmaceutical firm Novo Nordisk has announced plans for a significant expansion of its production facilities in China, expanding its capabilities to accommodate the increasing demand for its FlexPen, NovoPen...
SCOLR reports positive test results of AA technology
09-Nov-2004 - US drug delivery company SCOLR Pharma, announced it has filed a provisional patent application utilizing the company's patented amino acid technology for the Controlled Delivery Technology (CDT) extended release form...
08-Nov-2004
Mail-order can damage drugs, finds study
08-Nov-2004 - A new study has revealed that a commonly used asthma medication lost more than half its potency after being kept for just four hours in conditions akin to a mailbox...
Gene involved in most lung cancers found
08-Nov-2004 - Researchers from medical charity Cancer Research UK have discovered a new gene that protects against lung cancer, according to a study published today in the journal Proceedings of the National...
Synbiosis' system speeds up vaccine production
08-Nov-2004 - The development of antimicrobial therapies and vaccines to treat biological terrorism threats such as anthrax and smallpox has been made easier by an automated colony counting system, which the company...
Tiny sensor makes drug pumps safer
08-Nov-2004 - A tiny pressure sensor already sold in the automotive industry could improve the efficacy of pumps used to deliver drugs from implanted reservoirs, according to one of the scientists behind...
Upgradeable RFID may answer industry concerns
08-Nov-2004 - Printing solutions specialist Zebra Technologies, a specialist in radio frequency identification (RFID) labels, has launched two new UHF (ultra high frequency) EPC (electronic product code) multi- protocol printer/encoders, the Zebra...
DSM cuts jobs at vitamin C plant
08-Nov-2004 - Dutch chemicals group DSM is axing 200 jobs at its vitamin C plant in Dalry, Scotland in the next wave of a company-wide cost-cutting programme.
Fast-growing RNAi market shows no signs of slowing
08-Nov-2004 - RNA interference (RNAi) therapeutics to combat human illnesses such as Huntingdon's disease, amyotrophic lateral sclerosis and hepatitis C are set to fuel the rapid growth in the RNAi research product...
People on the move
08-Nov-2004 - In-Pharmatechnologist's periodic round up of personnel moves in the pharmaceutical sector includes a crop of new chief executives and senior managers across the pharmachem, drug development and manufacturing sectors.
05-Nov-2004
Enzyme becomes potential drug target
05-Nov-2004 - US researchers have revealed the results of a study that show an enzyme that normally alters the activity of other protein molecules in cells may also help prevent lung cancer.
Lab supply firms feel effects of consolidation
05-Nov-2004 - The major laboratory supply companies in the US have a mixed bag of results in the third quarter of 2004, with exceptional items eating into profits as a consequence of...
04-Nov-2004
Baxa launches device for hazardous drugs reconstitution
04-Nov-2004 - The safety hazards of reconstituting toxic drugs has been addressed by Baxa, who have launched a dual purpose needle that prevents environmental contamination that can occur during the process of...
EU could allow generics of patented drugs for countries in need
04-Nov-2004 - The European Union has put forward new legislation that would allow generic manufacturers to make drug products with in-patent active pharmaceutical ingredients, provided that they are intended for use in...
IDS technology receives FDA approval
04-Nov-2004 - Dimensional Dosing Systems has received US Food and Drug Administration (FDA) approval for over-the-counter use of the company's insulin dosing technology in clinical trials.
BioProgress on top in capsule legal wrangle
04-Nov-2004 - UK cellulose film specialist BioProgress has won another round in its patent dispute with Stanelco Fibre Optics over the use of radiofrequency welding to make polymer capsules.
Emerson, GE link up on protein purification
04-Nov-2004 - Emerson Process Management has formed an alliance with GE Healthcare aimed at providing faster, simpler and more cost-efficient solutions for protein purification - the most critical operation in manufacturing of...
03-Nov-2004
Stem cells target drugs at tumours
03-Nov-2004 - Researchers have used engineered stem cells to zero in on tumours to become part of the supporting tissue. They can then act as vehicles for drugs that are pumped into...
Dow extends UT Austin pact on solubilisation
03-Nov-2004 - Dow Chemical has renewed a collaboration with the University of Texas at Austin (UT Austin) in the US aimed at developing a new technology to improve the solubility and bioavailability...
Italy looks at small packs to cut waste
03-Nov-2004 - The budget committee of Italy's Lower House of Parliament has approved a plan by the opposition to require the national medicines agency, the AIFA, to draw up a method of...
Report puts pharma industry under further pressure
03-Nov-2004 - According to a report, it takes 7-10 years to develop and market a drug with costs exceeding $800 million (€625 million). This revelation is set to add to the pressure...
Alcoa brings shrink sleeve into pharma sector
03-Nov-2004 - The shrink sleeve label is a staple of the food and beverage industry, but has not been widely adopted for pharmaceutical use. However, this could change as the technology has...
New azithromycin format is one-dose RTI killer
03-Nov-2004 - A one-dose, microsphere formulation of azithromycin is as effective as several days' treatment with other drugs for respiratory tract infections (RTIs), according to new clinical data.
GSK is Singapore CMO's first customer
03-Nov-2004 - Singapore-based biologics contract manufacturer, A-Bio Pharma has won its first contract after entering into a process development and clinical supply service agreement with GlaxoSmithKline's vaccine division, GlaxoSmithKline Biologicals.
02-Nov-2004
Pfizer agrees to produce drug alternative to HRT
02-Nov-2004 - US drug giant Pfizer, has signed a license agreement to market a specific class of non-hormonal drugs to treat the hot flushes associated with menopause. The new drug,currently in development,...
01-Nov-2004
Capital investment news round-up
01-Nov-2004 - European companies have announced hefty spending on new manufacturing facilities this month, suggesting that despite a difficult operating environment the pharmaceutical sector is still prepared to make significant capital investments
Collaboration aims at improved insulin pump
01-Nov-2004 - Animas has entered into a license and development agreement with Debiotech, which aims to develop the next generation of insulin pumps and micro needles using Debiotech's Micro Electromechanical Systems (MEMS)...
Pall buys protein purification unit from Ciphergen
01-Nov-2004 - Separation and filtration giant Pall is to pay $32 million to acquire BioSepra, a division specialising in protein purification technologies, from Ciphergen.
Virtual room makes knowledge out of data
01-Nov-2004 - A team at Purdue University in the US is developing a virtual 'data cave' for scientific discovery that uses high-performance computing and artificial intelligence software to display information and interact...
New technique blocks Alzheimer's plaque build-up
01-Nov-2004 - A new therapeutic technique based on a small molecule working in tandem with a larger protein has been shown to block accumulation of the brain-clogging amyloid protein seen in Alzheimer's...
Cambrex makes €33m third quarter loss
01-Nov-2004 - Cambrex has recorded a loss in the third quarter of this year after writing down goodwill in its biopharma division in a move that paints a pessimistic picture of the...
Microfluidics makes short work of emulsions
01-Nov-2004 - Emulsions are widely used in the formulation of pharmaceuticals, cosmetics and foods, and researchers are continually striving to increase the complexity of emulsions as a delivery vehicle.
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