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Headlines > July 2005

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29-Jul-2005

MAP Pharma extends respiratory alliance with Elan

29-Jul-2005 - MAP Pharmaceuticals has broadened its agreement with Elan Corp to develop improved formulations of respiratory drugs to include combination asthma treatments and inhaled drugs for other lung diseases.

28-Jul-2005

MIT engineers anti-cancer smart bomb

28-Jul-2005 - Scientists have developed a nanoparticle that can penetrate a tumour, cut off its blood supply and release a lethal dose of anti-cancer toxins, while leaving healthy cells unscathed.

IMA looks to China as Western markets fail to pick up

28-Jul-2005 - Italian processing machinery company IMA Group has decided to increase its investment in a Chinese joint venture to tap into a growth market at a time when its established territories...

Pilot-scale freeze drier launched by BPS

28-Jul-2005 - Biopharma Process Systems of the UK has extended the range of freeze driers it offers in the UK and Ireland with the launch of VirTual for pilot scale bulk freeze...

R&D spending per NME declines

28-Jul-2005 - According to a recent survey, the pharma industry spent an estimated $1.25 billion for each new molecular entity (NME) approved by the FDA in 2004. The figure represents the second...

Pharma managers sought as science journalists

28-Jul-2005 - Novis is currently seeking experts to develop as science journalists across several of its pharmaceutical and food industry news services.

27-Jul-2005

DSM tops analyst forecasts in second quarter

27-Jul-2005 - Dutch chemicals group DSM reported better than expected second quarter results today, as higher selling prices in its industrial chemicals unit and lower fixed costs boosted margins, write Dominique Patton...

Evotec wins service contract from P&G Pharma

27-Jul-2005 - Germany's Evotec is to provide a broad range of pharmaceutical discovery and chemical development services to Procter & Gamble Pharmaceuticals in a lift for its outsourcing business.

Biopharma pulls Lonza back on track in first half

27-Jul-2005 - Swiss chemicals firm and contract manufacturer Lonza fulfilled its promise of stronger financial results in the first half of 2005, with profits coming in at the lower end of the...

Kirin buys transgenic cow firm Hematech

27-Jul-2005 - Japan's Kirin Brewery Co has bought Hematech of the US, acquiring the latter's core technology for the production of bovine-derived human polyclonal antibodies which could be useful in the development...

26-Jul-2005

FlexPac to expand into pharma after Blackard acquisition

26-Jul-2005 - The acquisition of Flexible Packaging (FlexPac) of the US by the Blackard Group will spur the development of the company's technology into new industrial sectors, including pharmaceuticals.

Teva to regain generics lead with Ivax purchase

26-Jul-2005 - Teva Pharmaceutical Industries continued its bid for world domination in the generic pharmaceuticals sector yesterday with a $7.4 billion cash and stock bid for US company Ivax, reports Phil Taylor.

Price increases keep Akzo Nobel on track in 2Q

26-Jul-2005 - Dutch pharmaceuticals and chemicals giant Akzo Nobel reported second-quarter sales of €3.34 billion, up 6 per cent from the comparable period in 2004, thanks to price increases that overcame flat volumes.

Laboratory tool reveals linked loci

26-Jul-2005 - An improved new statistical method developed by genome researchers, is set to streamline the computation required to identify the potential locations in the genome, as well as linking more gene...

Acambis commences C. difficile vaccine trial

26-Jul-2005 - Acambis has commenced clinical trials of its investigational vaccine against Clostridium difficile (C. difficile) - a common hospital-acquired infection, in which a new virulent strain has emerged, causing sharp increases...

Alliance aims to improve actinomycete production

26-Jul-2005 - Microbia has entered into a research collaboration with A*STAR's Bioprocessing Technology Institute (BTI) in Singapore to improve the efficiency of pharmaceutical production from actinomycete bacteria.

25-Jul-2005

Lab-scale blender boasts NIR analysis

25-Jul-2005 - Buck Systems, part of Niro Pharma Systems, has launched a laboratory-scale blender that allows users to analyse powders as they are being blended and monitor changing powder characteristics, achieving the...

Scientists discover molecule potential for Alzheimer's

25-Jul-2005 - Scientists from the University of California have discovered three molecules that show great potential in the development of new Alzheimer's drugs. The new therapy targets a protein that accumulates in...

Merck sees turnover rise across chemicals, pharma

25-Jul-2005 - Chemicals and pharmaceuticals firm Merck KGaA saw turnover rise but pretax earnings dip in the second quarter of 2005, although the results were skewed by the gain from its divestment...

Drug treatment mimics circadian rhythms

25-Jul-2005 - UK company Diurnal has received orphan product designation from the European Commission for a novel treatment that uses a drug delivery technology to match the body's circadian rhythms.

Maxim issued with novel cancer drug patent

25-Jul-2005 - Maxim Pharmaceuticals has been issued with a US patent that covers a novel class of potent apoptosis inducers with vascular targeting activity that inhibits microtubule formation - a prime drug...

Chiron vaccine facility will miss Begrivac production targets

25-Jul-2005 - Chiron says it will be unable to supply any Begrivac influenza vaccine to markets outside the US during the 2005/6 flu season, just days after admitting it has sterility problems...

Filters up, but bioreactors hold back Sartorius in 1H

25-Jul-2005 - Lab and process equipment company Sartorius closed the first half of 2005 with increases in sales revenue and earnings, with a good performance by its filter business driven by demand...

22-Jul-2005

Q Chip extends MicroPlant collaboration

22-Jul-2005 - Cardiff-based drug delivery company Q Chip has extended its collaborative research deal with Biocompatibles International, a medical device company focused on the treatment of cardiovascular disease, cancer and benign tumours.

Provectus begins cancer treatment trials

22-Jul-2005 - Provectus Pharmaceuticals are to begin phase 1 clinical trials of new cancer treatment, PV-10, the company's new drug candidate for the treatment of metastatic melanoma (the most aggressive form of...

Ekisigent launches next-gen proteomics system

22-Jul-2005 - Eksigent Technologies launches its liquid chromatography system for nanospray mass spec analysis that allows sample loading at higher flow rates, making it suitable for proteomics and biomarker discovery applications.

Alcan launches childproof pharma packaging

22-Jul-2005 - Alcan has launched the Guardlid, a new child-resistant pharmaceutical packaging solution that has been designed specifically for use in the pharmaceutical and healthcare markets.

Nabi Biopharmaceuticals opens new facility

22-Jul-2005 - Nabi Biopharmaceuticals has opened its new vaccine manufacturing facility in which commercial quantities of StaphVAX [Staphylococcus aureus Polysaccharide Conjugate Vaccine] will be produced. StaphVAX is currently in phase III development...

21-Jul-2005

UCLA chemists create Nano Valve

21-Jul-2005 - UCLA chemists have created the first nano valve that can be opened and closed at will to trap and release molecules. The nano valve could potentially be used as a...

Occam obtains CE approval for stent

21-Jul-2005 - Biosensors International Group has announced that its Netherlands-based subsidiary, Occam International B.V. has received Conformite Europeene (CE) Mark approval for the Group's first drug eluting stent (DES), Axxion.

New Sanofi plant increases vaccine production

21-Jul-2005 - Sanofi Pasteur is to increase US influenza vaccine capacity as plans to construct a new plant get underway. The new facility is expected to be up and running in time...

Millipore posts stronger revenue, but profits close

21-Jul-2005 - Manufacturing consolidation and acquisition costs helped reduce net income as Millipore revealed its 2005 second quarter financial results. The company has just completed the purchase of two companies with the...

Merrion issued drug delivery patent

21-Jul-2005 - Oral drug delivery specialists, Merrion Pharmaceuticals, have been issued with a patent that covers new peptide compounds which can be physically or chemically complexed with an active substance, either a...

20-Jul-2005

Cylene enters novel cancer agent trials

20-Jul-2005 - A first-in-class small molecule with a novel mechanism of action that selectively induces cancer cell death is to undergo phase I clinical trials. Its makers, Cylene Pharmaceuticals have claimed the...

Sigma-Aldrich launches research tools

20-Jul-2005 - Sigma-Aldrich has launched a handful of laboratory equipment and technological developments that could prove useful in drug discovery. The life science company is currently in the midst of a reorganisation...

Questcor gains API manufacturing transfer approval

20-Jul-2005 - Questcor Pharmaceuticals has announced the Food and Drug Administration (FDA) has approved its application to transfer the manufacturing process of the Active Pharmaceutical Ingredient (API) in the company's adrenocorticotropic hormone...

19-Jul-2005

Invitrogen looks down under for bovine sera

19-Jul-2005 - Invitrogen has opened a bioproduction facility in Australia to make bovine sera products and reagents used in basic research and the production of vaccines and biotherapeutic drugs.

Nasal calcitonin delay hits Upsher-Smith Labs

19-Jul-2005 - US pharmaceutical company Upsher-Smith Laboratories has been forced into staffing cuts and a restructuring exercise by delays in the US Food and Drug Administration's review of its nasal calcitonin product...

Bayer plans to expand Aspirin facility

19-Jul-2005 - Bayer has announced an expansion of its Bayer Bitterfeld plant in Saxony Anhalt, Germany, the world's largest production facility for Aspirin.

Lester Crawford wins top FDA post

19-Jul-2005 - Lester Crawford was confirmed yesterday as the new Commissioner of the US Food and Drug Administration, having already served for more than a year in the post.

Able Labs files for bankruptcy protection

19-Jul-2005 - The trials and tribulations affecting US generics maker Able Laboratories took a decisive turn yesterday when the company filed for Chapter 11 bankruptcy protection, reports Phil Taylor.

New company enters pharmacogenomics

19-Jul-2005 - The new company has been launched to provide laboratory-based drug discovery and clinical trials services to the pharmaceutical and biotech industries. Lab21 services include lead identification and optimisation, resistance profiling,...

18-Jul-2005

Abingworth raises $53M for drug investment

18-Jul-2005 - Life sciences investment group Abingworth Management has announced the initial Abingworth BioEquities Fund (ABE) has raised $53 million (€44 million) to invest across the life sciences field including human therapeutics.

Drug may repair DMD heart damage

18-Jul-2005 - Scientists believe they may have found a way to prevent heart failure associated with the genetic disease, Duchenne muscular dystrophy (DMD). The study is the first to demonstrate a new,...

Crop biomanufacturing of enzyme gets underway in US

18-Jul-2005 - German biotechnology company ICON Genetics is to start field trials of a transgenic tobacco crop that will be used to produce an enzyme with potential as an active pharmaceutical ingredient...

Second Chiron plant has sterility problems

18-Jul-2005 - US drugmaker Chiron is facing a significant shortfall in the volume of influenza vaccine it will be able to ship to markets outside the US as a result of sterility...

REACH compromise aimed to alleviate SME fears

18-Jul-2005 - The rapporteur trying to finesse the controversial REACH legislation through the European Parliament, Guido Sacconi, has formulated a compromise that aims to alleviate fears that the regulations could pose a...

VWR expands in Europe with TSL buy

18-Jul-2005 - US-based laboratory equipment specialist VWR International has boosted its presence in Europe via the acquisition of Technical Service Lab, a Dutch calibration and validation company.

rap.ID launches new particle identifier

18-Jul-2005 - A particle finder, which can determine particle size, number and shape within 15 seconds, has been launched by German equipment supplier rap.ID, which believes such technology could solve the problem...

15-Jul-2005

DSM takes control of biologics unit

15-Jul-2005 - DSM Pharmaceutical Products has taken full control of its biologics manufacturing unit after buying out its Canadian joint venture partner.

New technique enhances ADME/Tox predictions

15-Jul-2005 - A new in silico technique for generating enhanced predictions for ADME/Tox research could have new implications in developing novel drug techniques in combating drug-resistant infectious diseases and cancer.

Guidance from EMEA on plastic packaging

15-Jul-2005 - The European Medicines Agency has published updated guidelines on the use of plastic packaging in pharmaceuticals, in a bid to help packagers select the best and safest materials for their...

T-cell control discovery boosts new drug research

15-Jul-2005 - Scientists have taken a major step forward in autoimmune disease research after the process of T-cell trafficking through the blood and lymph nodes to fight infection was discovered. Controlling this...

American Pacific buys pharma ingredients firm

15-Jul-2005 - American Pacific Corp has agreed to acquire the assets of Aerojet Fine Chemicals for $119 million (€98m), in a deal which APC said would give it access to 'fast-growing pharmaceutical markets'.

Sigma-Aldrich restructures research units

15-Jul-2005 - Sigma-Aldrich is reorganising its operating structure, although its fine chemicals unit SAFC will be unaffected by the restructuring.

Merrion wins US patent for oral delivery tech

15-Jul-2005 - Merrion Pharmaceuticals has been granted a US patent for a drug delivery technology that improves the transport of medicines across biological membranes.

14-Jul-2005

Gene therapy market suffers growth setbacks

14-Jul-2005 - New analysis into the gene therapy market reveals that toxicological complications and poor therapy efficacy have hampered the growth of this sector in which new ways must be found to...

13-Jul-2005

LSBC boosts dental caries antibody production

13-Jul-2005 - US firms Large Scale Biology Corp and privately-held Planet Biotechnology have expanded their biomanufacturing program to extract and purify the latter's lead product, CaroRx, a plant-made antibody to control dental...

AK Pharma retreats from US market

13-Jul-2005 - Engineering and construction company Aker Kvaerner Pharmaceuticals has decided to cease operations at its office in Bridgewater, New Jersey, US.

Infinity initiates Phase I myeloma drug trial

13-Jul-2005 - Infinity Pharmaceuticals announced the initiation of a phase I clinical trial of the company's lead investigational anticancer agent for the development of a potential treatment for patients with multiple myeloma....

Chr Hansen patents low-cost tablet coating

13-Jul-2005 - Scientists at Chr Hansen's US research operations have developed a gum acacia-based film coating, suitable for use in pharmaceuticals, that combines low cost, long shelf life and low shipping costs.

Cardinal licenses talking pill bottle

13-Jul-2005 - Cardinal Health has signed an agreement with a software company to distribute a talking pill bottle called Rex.

12-Jul-2005

Applied Bio, Invitrogen forge proteomics alliance

12-Jul-2005 - Applied Biosystems has teamed up with Invitrogen to combine forces on providing proteomic analyses and biomarker studies in drug discovery and disease research.

Able interim CEO walks as FDA sends in 483

12-Jul-2005 - Ailing US generics company Able Laboratories lost its second chief executive in six weeks on Friday, after Richard Mauro tendered his resignation.

Finding sheds light on drug toxicity

12-Jul-2005 - Researchers in the US have uncovered the mechanism underlying a genetic tendency for some patients to be more susceptible to side effects of drugs than others.

11-Jul-2005

Disposable bioreactor boosts protein yields

11-Jul-2005 - A disposable flask bioreactor designed by Swiss company Integra Biosciences has been shown to boost cell densities in mammalian cell culture by a factor of 10 in a study.

Cardinal makes first GMP antibody batch

11-Jul-2005 - Cardinal Health has completed the manufacturing of an antibody destined for human clinical trials, using a cell line that was made with its patented GPEx (Gene Product Expression) technology.

Millipore buys NovAseptic for $91m

11-Jul-2005 - Millipore continued its shopping trip for new businesses last week with the purchase of NovAseptic, a Swedish company specialising in aseptic processing equipment used in the production of pharmaceutical and...

08-Jul-2005

MS collaboration tackles water contaminant

08-Jul-2005 - Applied Biosystems and joint venture partner MDS Sciex have formed an alliance with Dionex to develop combined ion chromatography and mass spectroscopy approaches for the accurate and sensitive measurement of...

Triple reuptake inhibitors will inherit depression market

08-Jul-2005 - A new class of antipressant - dubbed the triple reuptake inhibitor - will in time come to dominate the market for depression treatments and achieve multibillion dollar revenues, according to...

Thermoregulator boosts process yields

08-Jul-2005 - Radleys of the UK has introduced a new refrigerated heat circulator that can improve the efficiency of process development, according to the company.

07-Jul-2005

Study mulls science conflict of interest

07-Jul-2005 - The controversy surrounding new conflict-of-interest regulations at the US National Institutes of Health has prompted the Science Advisory Board to look closely at what constitutes acceptable industrial pursuits for government...

Belgium is OECD star on biopharma innovation

07-Jul-2005 - A recent study designed to assess biopharmaceutical innovation in the member states of the Organisation for Economic Cooperation and Development has found that, in terms of innovation and biotechnology industry...

Vernalis buys intranasal opioid company

07-Jul-2005 - UK biotechnology company Ionix Pharmaceuticals is gearing up for acquisition by Vernalis in a share-based deal valuing Ionix at around £12.5 million (€18.2m).

06-Jul-2005

Celliance extends bovine albumin range

06-Jul-2005 - Celliance has introduced a new bovine albumin product, manufactured exclusively from animals originating in Australia, that is aimed at applications such as pharmaceuticals where there is a need to ensure...

West Pharma continues acquisitive spree

06-Jul-2005 - West Pharmaceutical Services is planning to buy Israel's Medimop Medical Projects, which develops disposable medical devices for the mixing, transfer, reconstitution and administration of injectable drugs.

Millipore expands in contract micro testing

06-Jul-2005 - Millipore has bolstered its position in the contract testing business with the acquisition of a Dutch contract laboratory.

Gene scanning technology advances disease research

06-Jul-2005 - A new gene scanning technology, developed by researchers in the UK, is set to have a major impact on healthcare in the future with the potential to lead a very...

New HIV drug class forms deal focus

06-Jul-2005 - ViroLogic, announced the signing of a multi-year, $4.8 million (€4 million) service agreement with Schering-Plough Research Institute, to use ViroLogic's novel HIV resistance testing technology to support Schering-Plough's drug R&D...

05-Jul-2005

Spooner Vicars planning pharma expansion

05-Jul-2005 - A major food equipment manufacturer has announced plans to expand into pharmaceutical equipment and processing, following its purchase from Italian owners CIR last month.

Emergent acquires vaccine production technology

05-Jul-2005 - Emergent Biosolutions has announced it has acquired Microscience, in a deal that adds proprietary platform technology in oral vaccine delivery. The deal also adds to Emergent's European presence in the...

Supply chain deal aims to improve security

05-Jul-2005 - Applied DNA Sciences has entered into collaboration with Advanced Coding Systems (ACS), in a deal to develop security products for brand protection and electronic article surveillance for pharmaceutical supply chain...

New pathway opens CF treatment possibilities

05-Jul-2005 - US researchers have identified a specific pathway that causes inflammation in lung tissue, a discovery that could help in the design of more targeted drug treatments for patients with various...

People on the move

05-Jul-2005 - In-PharmaTechnologist.com reports its periodic round-up of personnel changes in pharmaceutical manufacturing and development.

UK packaging waste targets 'skewed', company claims

05-Jul-2005 - The UK's figures on recycling waste is skewed because companies are exporting their problem rather than increasing reprocessing rates, the UK's second largest packaging waste compliance company claims.

EU approves drug delivery technology studies

05-Jul-2005 - NMT Medical announced that the company has received approvals to initiate studies designed to evaluate its new closure technology. The collagen matrix used in the technology has the potential to...

04-Jul-2005

Balchem raises pharma profile with Loders acquisition

04-Jul-2005 - Balchem has acquired the encapsulation and agglomeration business of IOI Group - part of Loders Croklaan USA - in a move that extends its activities in the food and pharmaceutical...

Topical drug delivery gel patented by Foamix

04-Jul-2005 - Israeli drug delivery firm Foamix has been awarded a US patent for its OilGel technology, a semisolid matrix which turns into a liquid when rubbed onto the skin and can...

Pharma, food driving batch control market

04-Jul-2005 - Batch control systems are becoming increasingly used by the pharmaceutical and food industries as they increasingly rely on automation to improve productivity and product quality.

Able unable to meet investors

04-Jul-2005 - The manufacturing compliance problems affecting US generic drug manufacturer Able Laboratories, which have prompted a huge recall of its entire product range, show little signs of being resolved, reports Phil...

01-Jul-2005

GSK says Paxil CR manufacturing problems are over

01-Jul-2005 - UK-headquartered pharma giant GlaxoSmithKline says it has overcome the manufacturing problems that caused it to voluntarily withdraw its antidepressant Paxil CR (paroxetine) and diabetes drug Avandamet (metformin and rosiglitazone) from...

EMEA finalises EU pharma guideline procedure

01-Jul-2005 - The European Medicines Agency (EMEA) has finalised a new procedure designed to make the process for the development, consultation, finalisation and implementation of pharmaceutical guidelines clearer.

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