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Headlines > May 2007

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31-May-2007

Softgel formulation to challenge Abbott drug

Two firms have announced a licence and supply agreement for a novel formulation of valproic acid presented as a softgel capsule, which could challenge Abbott's top selling drug Depakote (divalproex sodium).

Solution to supply chain issues encoded in barcode

A magic bullet for the pharmaceutical supply chain has entered the stage as radio frequency identification (RFID) technology attempts to fix up its teething problems.

New credentials for pharma industry

Pharmaceutical manufacturing professionals will be able to have their skills formally recognized in a new certification, it was announced.

Semi-synthetic paclitaxel production starts in Italy

Italian company Indena has announced it has invested in a new facility for the semi-synthetic production of a potent cytotoxic active principle.

Animal-free cell culture ingredients hit the shelves

Danish firm Novozymes has launched its first range of animal-free recombinant cell culture ingredients from its new business unit in the UK, offering biopharmaceutical firms an alternative to traditional serum-based production methods.

Product news in brief

LabTechnologist.com brings you a round-up of some of the latest product news, with new releases from Affymetrix, Genevac, Mettler Toledo, Qiagen and Thermo Fisher Scientific.

GMP peptide plant planned downunder

A fund to promote biotech collaborations between Australia and New Zealand has awarded a lump sum to two Antipodean firms which will result in a new good manufacturing practice (GMP) compliant peptide manufacturing plant in the under-served Southern Hemisphere.

Neural data recorder from ADInstruments

ADInstruments has launched its Neuro Amp EX to improve neurological data collection from animals and humans during drug candidate testing by reducing noise and improving ease of use.

New class of biologic may bring psoriasis relief

New research presented yesterday has revealed that a new class of biologic drug may bring new relief to those suffering from the skin condition psoriasis.

Bird flu blood could hold key to new cure

Antibodies from the blood of bird flu survivors could hold the key to developing an alternative prevention and treatment for the deadly H5N1 virus for the 6bn people potentially at risk should a pandemic emerge.

Symetix launches optical inspection system for solid-dose pharmaceuticals

Symetix has launched an optical inspection system for solid-dose pharmaceuticals, with a particular emphasis on softgel capsules.

Q Chip launches effortless PCR

The launch of a new gel-based PCR 'lab-in-a-bead' promises more accurate PCR experiments by doing away with the potential for measuring errors.

30-May-2007

Alcohol dependence drug shows financial promise

Sales of Alkermes's new drug for alcohol dependence are on a high following its release in June last year, and have contributed a hefty portion to the company's coffers.

Ethical reputations of top pharma firms revealed

The latest ethical reputations of the world's largest pharmaceutical companies have been revealed, with GlaxoSmithKline (GSK) emerging as big pharma's Mother Theresa, according to a recently-released compilation by Geneva-based ethical-monitoring firm Covalence.

MDS Pharma ends FDA probe nightmare

MDS Pharma has decided to continue the 'consolidation' of its Canadian operations by putting an end to some activities at its Montreal facility, cutting 160 jobs.

ISO invigorates packaging standards

Alcan Packaging Kreuzlingen is the latest company to receive certification for the new ISO standard for primary packaging, becoming the first flexible packaging firm in the world to achieve the accreditation.

People on the move: Pharmaceutical manufacturing

CellCyte Genetics, Whatman, Nektar Therapeutics, Anesiva and Hyaluron Contract Manufacturing have all had people on the move in the world of pharmaceutical manufacturing.

Vivalis tech fuelling flu vaccine development

Biopharma firm Vivalis has announced several licence agreements for its proprietary cell line technology, adding to the list of companies applying the technology to develop and commercialise new human influenza vaccines.

CMO Daiso licences chiral synthesis tech from Harvard

The fine chemicals division of Japanese contract manufacturer Daiso has taken out a license to a highly-selective technology used to synthesise chiral molecules.

Drug delivery in liposomes could be thing of the past

The use of liposomes as a drug delivery system could be old news if a new and improved lipid-like nanoparticle lives up to its potential, according to a team of Austrian and American scientists.

29-May-2007

Iomai changes tack with flu vaccine patch

Iomai Corporation is scoping out new antigen possibilities after its patch-based vaccine for seasonal influenza failed to match the immune response of the same vaccine administered by injection in a Phase I clinical trial.

New president of manufacturing for Eli Lilly

Eli Lilly has announced the appointment of Dr Frank Deane as the new president of its manufacturing operations.

FluMist problems drag on

Despite promising opinions regarding the extension of the age indication for MedImmune's inhalable flu vaccine FluMist, the US Food and Drug Administration (FDA) is withholding any final decisions until manufacturing violations have been rectified.

UK laboratory equipment market 'healthier'

The UK laboratory equipment market is a healthier place to invest than six months ago with companies increasing their returns on investments.

West targets growing Asian market for investment

With Asia increasingly becoming the destination of choice for manufacturers and the domestic market blossoming, a major components manufacturer has singled out its Singapore facility for a multi-million dollar expansion.

CMOs driving disposable demand

Contract manufacturing organisations (CMOs) have been pinpointed as a growth driver of single-use biopharmaceutical manufacturing technologies.

Industry news in brief

LabTechnologist.com brings you its periodic round-up of industry news with news from 454 Life Sciences, Biobase, Guava, Leica, Carl Zeiss, Whatman and GE Healthcare.

Parallel trade pushing fakes?

Batches of two fake blockbuster drugs are being recalled after counterfeits made their way into the UK supply chain via parallel distribution, adding fuel to the debate on the security of the practice in the EU.

Oral calcitonin into Phase III for osteoarthritis

An oral formulation of salmon calcitonin based on Emisphere Technologies' eligen delivery system has entered Phase III clinical trials for the treatment of osteoarthritis.

Increased intelligence through genetic engineering

Scientists who have genetically engineered mice to be more intelligent, claim the results could lead to new treatments for Alzheimer's, post-traumatic stress disorder or drug addiction.

Asian contract manufacturers key to curbing EU generics costs

Using low cost contract manufacturing destinations are the key to helping generics firms in Europe keep their drugs cost-effective, says a Frost & Sullivan report.

Micromet, Nycomed join forces on anti-GM-CSF antibodies

Suppressing granulocyte macrophage colony-stimulating factor (GM-CSF) to tackle inflammatory and autoimmune diseases is the concept behind a new worldwide collaboration between German-American biopharmaceutical company Micromet and Denmark's Nycomed.

ESS to distribute filling machine

ESS Technologies has added Bergami's new TF 80 automatic tube filling and closing machine to its offering to US pharmaceutical manufacturers.

NIST launch proteomics reference materials

The National Institute of Standards and Technology (NIST) has issued its first ever reference material to improve the performance and reliability of proteomics research.

FDA panel set to decide on expanded use for Tysabri

Elan and Biogen Idec have announced that a US advisory panel has set a date to review their potential blockbuster MS drug Tysabri (natalizumab) for the treatment of Crohn's disease.

24-May-2007

Packaging machinery purchases set to plateau

Packaging machinery purchases in the US are expected to level off in 2007 as buyers exercise caution in the face of uncertainty in the US economy.

YM's revamped MAb facility gets thumbs up

YM BioSciences today announced that the upgraded manufacturing facility for the firm's humanized monoclonal antibody (MAb) for the treatment of cancer has successfully passed a series of regulatory reviews.

Product news in brief

LabTechnologist.com brings you a round-up of some of the latest product news, with developments at Agilent, Bruker Daltonics, Labcyte, Millipore, NoAb, PerkinElmer, Radleys and Sigma-Aldrich.

Advances in Microarray Technology

The latest Advances in Microarray Technology (AMT) conference, held in conjunction with the Lab-on-a-Chip World Congress highlighted the movement of the fields from the research lab into diagnostics.

Nanopoint the way to live cell imaging

Nanopoint has released its cellTRAY imaging system that enables time lapse imaging of individual cells while reducing experiment costs.

Acambis brings smallpox vaccine production in-house

UK biotech firm Acambis has decided to bring the manufacturing of its soon to be approved smallpox vaccine in-house while its agreement with contract manufacturer Baxter comes to an end.

Alembic seals epilepsy drug delivery deal

Indian firm Alembic has landed a licensing deal with biopharma heavyweight UCB to apply the company's novel drug delivery system for a once-a-day version of UCB's market leading epilepsy drug.

MFIC to bring microfluidics to drug formulation

MFIC is looking to introduce a new microfluidic system that could help pharmaceutical and biotechnology companies to manufacture difficult to formulate drugs.

AMRI snaps up two manufacturing sites in India

Albany Molecular Research (AMRI) has followed up its push into new markets for its drug discovery operations by tapping into the well-established trend for sourcing contract pharmaceutical manufacturing from the lower-cost Asian region.

Inovio's electroporation tech delivers the goods in trial

Inovio Biomedical, a US company developing novel DNA immunotherapies and other treatments based on electroporation technology, has reported interim data from a Phase I/II clinical study showing that its MedPulser system significantly enhanced the potency of an experimental prostate cancer vaccine.

Inhaler solution to premature ejaculation hasn't come too soon

The end of premature ejaculation is in sight as a simple inhalation of a drug promises to prolong the action under the sheets.

23-May-2007

Draxis gets two thumbs up in inspection

Canada-based Draxis Health has passed a US Food and Drug Administration (FDA) inspection with flying colours after contracting out its manufacturing services to two new clients.

Once-a-day pharyngitis drug one step closer

The US Food and Drug Administration have finally accepted Advancis Pharmaceutical's new drug application (NDA) for its once daily amoxicillin Pulsys product for tonsillitis and pharyngitis.

ACCU-BREAK aims to divide and rule with tabletting tech

Novel tabletting technology developed by US company ACCU-BREAK Pharmaceuticals promises to solve the problem of uneven doses when pills are split by hand.

'Mini-antibodies' in first-ever clinical trials

'Miniature antibodies' are set to enter clinical trials for the first time ever, potentially paving the way for more effective antibody therapies that are also cheaper to manufacture.

People on the move: Pharmaceutical Manufacturing

Hana Biosciences, SupplyScape, Galenea, and Mpex Pharmaceuticals have all had people on the move in the world of pharmaceutical manufacturing.

International market boosts Dr Reddy's revenue

India-based Dr Reddy's Laboratories has boosted its revenue by 168 per cent for the 2006 year, fuelled by a strengthening position in the international market.

New insulin product takes the nasal route

A young start-up company is gearing up to challenge the likes of Pfizer by developing a new insulin product, based on its novel nano-based intranasal delivery technology.

Thailand gets $2m WHO vaccine boost

Thailand is the first recipient of six major grants the World Health Organization (WHO) is distributing to developing countries to establish in-country manufacturing capacity for influenza vaccine.

22-May-2007

QLT to shed drug delivery platform

Biopharma firm QLT has decided to shed a chunk of its Atrigel drug delivery products and platform in a bid to improve profitability at the company.

Alnylam hooks up with MIT for RNAi therapeutics delivery

US company Alnylam Pharmaceuticals has consolidated its relationship with researchers from the Massachusetts Institute of Technology (MIT) by signing an agreement to sponsor a five-year program at the Institute's Center for Cancer Research, focused on the delivery of therapeutics based on RNAi interference.

Molecular Insight increasing radiopharmaceutical output

Molecular Insight Pharmaceuticals is buying a commercial-scale radiopharmaceutical manufacturing facility in Texas for $3m as it moves towards increasing its manufacturing in the increasingly profitable pharmaceutical area.

New Bosch vial filling system promises clinical trial efficiency

Bosch Packaging Technology has launched the FLT1020 vial filling system, a scaled-down version of full-sized filling units that is geared specifically to use in the early stages of clinical trials.

Arrayjet Sprints into benchtop microarray production

Arrayjet's new Sprint benchtop inkjet microarray spotter promises to allow researchers the ability to design and print their own microarrays and array-based biosensors.

Industry news in brief

LabTechnologist.com brings you its periodic round-up of industry news with Inverness winning the bidding war for Biosite, Bio-Rad agreeing to purchase DiaMed, and news from Ciphergen, Eksigent, Siemens and Thermo Fisher Scientific.

Thermo's enhanced FT-IR spectrometer

Thermo Fisher Scientific has released a series of modules for its Nicolet 8700 FT-IR spectrometer to allow researchers to study fast reaction processes, chiral molecules and molecular films.

GMP certification positions Eden for clinical trial supply

Eden Biodesign, the biopharmaceutical development and manufacturing services company that runs the UK's National Biomanufacturing Centre (NBC), has now been cleared to produce investigational medicinal products for clinical trials at its facility in Speke, Liverpool.

Approvable letter no distraction for Shire's ADHD drug

An approvable letter for Shire's long-lasting formulation of its best-selling attention deficit and hyperactivity disorder (ADHD) drug Adderall is not the stumbling block it may appear says the company.

Amgen's US monopoly in EPO drugs may be close to its end

Swiss drug major Roche is facing a delay in bringing its EPO drug Mircera (continuous erythropoietin receptor activator) to market in the US after the Food and Drug Administration sent it an 'approvable' notice for the product.

Taro rescued from looming financial crisis

A white knight in the form of Indian-based Sun Pharmaceuticals, has rescued an Israeli company from a looming financial crisis by investing more than $400m in the company.

Not shaken or stirred - new disposable bioreactor hits market

A firm specialising in disposable equipment for the biopharmaceutical industry has introduced a new revamped bioreactor to its catalogue, dispensing with the traditional rocking and rolling mechanisms used in many bioreactors.

21-May-2007

RFID and real-time temperature monitoring combine

A UK-based technology company is part of a trio leading the way in innovative supply chain solutions by combining real-time temperature monitoring with a radio frequency identification (RFID) tag for the pharmaceutical industry.

Solvay wins plaudits for renewable epichlorohydrin process

Solvay's Epicerol process for manufacturing the chemical intermediate epichlorohydrin from glycerine won the Belgian company the 2007 Glycerine Innovation Award at the Annual Meeting and Expo of the American Oil Chemists' Society earlier this month.

Luck of the Irish brings new biologics base

Proposals for the construction of a new small-scale biologics manufacturing plant in Ireland courtesy of pharma heavyweight Pfizer emerged late last week.

Novel FluVacc vaccine enters Phase I trial

A live attenuated replication-defective vaccine against the influenza virus has started a Phase I clinical trial at the Medical University of Vienna in Austria.

End of GSK contract 'not the end of the world' for Cobra

The significance of the aborted deal between GlaxoSmithKline and Cobra has been exaggerated due to GSK's high profile and is not the end of the world, the British contract manufacturer said.

17-May-2007

MFIC rollercoaster continues as Q1 revenues drop 11 per cent

MFIC Corporation, which designs, manufactures and distributes high-performance Microfluidizer materials-processing equipment for the biotechnology, pharmaceutical, chemical, cosmetics/personal care and food industries through its Microfluidics Division, reported an 11.1 per cent drop in revenues to $2.80m for the first quarter of 2007.

Avecia ramps up manufacturing capacity

Massachusetts-based Avecia OligoMedicines has announced an expansion of its manufacturing facilities to accommodate increased production plans.

Firm expands to meet demand for Pancrecarb

US company Digestive Care (DCI) is quadrupling its manufacturing, research and development capacity following an increase in demand for its drug Pancrecarb (pancrelipase).

Product news in brief

LabTechnologist.com brings you a round up of brings you a round up of some of the latest news and releases from A2, GE Healthcare, Guava, Millipore, Radleys, Syngene and Thermo Fisher Scientific.

Agilent's bio-analytical revenues increase by 15 per cent

Agilent Technologies posted another set of strong results with growth in the bio-analytical division offsetting weaker performance in the electronic measurement division.

Thermo and Sartorius sign disposables agreement

Thermo Fisher Scientific and Sartorius have signed a supply agreement continuing the relationship between Sartorius and Thermo's recently acquired TC Tech.

Siemens launches software support for PAT implementation

Siemens is offering software support for the implementation of Process Analytical Technology (PAT) in the pharmaceutical industry with the launch of its Sipat package.

Lonza to combine microbial biopharma ops

Swiss contract manufacturer Lonza has decided to merge its US microbial biopharma business activities in a single location, three months after buying Cambrex's biopharma unit.

SkyePharma's GeoMatrix underpins another new drug formulation

UK company SkyePharma's GeoMatrix technology has been used to develop a new formulation of a hypertension drug which can provide lower drug doses.

Amgen knocked back as EPO competition looms

The decision of the US Supreme Court not to hear Amgen's appeal in a patent infringement case against Sanofi-Aventis and Shire, involving the anaemia drug Epogen (epoetin alfa), may weaken Amgen's position in keeping another rival off the US market.

ART's new imaging system

Advanced Research Technologies (ART) has launched a new imaging system for studying molecular events in small living animals to further our understanding of disease and treatment mechanisms.

Down on the biopharm

The critical role transgenic animals could play in the future of biopharmaceutical production has been tackled by a task force in a new report out this week.

16-May-2007

Sandoz moves to meet demands in injectables

Sandoz Canada is investing $80m in new facilities to meet demands for its generic sterile injectable pharmaceuticals.

Granules India tabletting plant to come onstream in August

Contract manufacturer Granules India is moving towards vertical integration, with a new tabletting facility scheduled to come onstream this August at the company's Gagillapur site near Hyderabad in India.

Lupin beefs up with Symbiotec steroids joint venture

India's Lupin Ltd is ramping up its active pharmaceutical ingredient (API) capability by teaming up with compatriot and corticosteroid specialist Symbiotec Pharmalab Ltd.

'No link' between autism and mercury-containing vaccines

The debate on the status of thimerosal in vaccines has reared its head again after a new study concludes there is no link between autism and the mercury preservative in vaccines.

Bacterially derived nanocells offer direct route for cancer therapy

Bacterially derived nanocells that can deliver chemotherapeutic drugs directly to cancer cells without the shortcomings of liposomal or viral carriers could be in clinical trials by the end of this year, an Australian biotechnology company says.

EU biosimilars regulations still need 'clarifications'

There are some areas of the European approval system for biosimilars that still need to be clarified, a panel of industry experts said during BIO 2007.

R&D outsourcing set to climb

Outsourced pharmaceutical R&D spending is set to increase at twice the expected rate of general R&D expenditure for the next five years, according to new research published this week.

Albemarle moves operations to newly bought DSM plant; cuts staff

US contract manufacturer Albemarle has announced it will move operations of its pilot plant in Ohio to its recently acquired manufacturing facility in Michigan.

15-May-2007

Production hitch stems US supply of ProQuad combination vaccine

Lower than expected yields of varicella zoster virus (VZV) have forced Merck & Co to run down US supplies of ProQuad, its all-in-one children's vaccine for measles, mumps, rubella (German measles) and varicella (chickenpox).

Revolutionary breath-freshener delivery system to combat rotavirus

It might look like a simple breath freshener dissolving mouth-strip but the John Hopkins University innovation is just steps away from cutting costs and saving thousands of lives from the deadly rotavirus.

FDA approves new inhalable COPD treatment

The market's first nebulized form of formoterol fumarate for chronic obstructive pulmonary disease (COPD) has been given the go ahead by the US Food and Drug Administration (FDA).

Pharmaceutical industry big driver as IMA continues on the up

The IMA Group's first quarter 2007 results continue to show growth following the firm's expansion in the pharmaceutical industry and its acquisitions over the last year.

New HIV tests look to speed up viral load analysis

Abbott Laboratories and Roche Diagnostics have both had HIV-1 tests approved by the US Food and Drug Administration (FDA) that should allow clinical laboratories to deliver viral load results faster.

Industry news in brief

LabTechnologist.com presents its periodic round up of recent industry news with the latest developments in the fight to buy Biosite as well as news from Agilent, Dionex, and Millipore.

Australian spin-offs pursuing nanotechnology innovations

A transdermal patch for needle-free delivery of insulin and a diagnostic test for rapid detection of meningococcal disease are among the products under development by two new Australian companies set up to commercialise the research outcomes of Nanotechnology Victoria (NanoVic).

Contract manufacturing news in brief

Robinson Pharma, Vybion, Prosensa, Diosynth Biotechnology, ImmunoGen and Novogen have all recently announced new contract manufacturing deals.

GMP for market's only synthetic gene delivery molecule

A French firm developing an innovative gene delivery tool has received a cash boost of €80,000 to ramp up good manufacturing processes for its synthetic delivery molecule.

Pharma dreams of greener future

More efficient ways to make amides and removing the need to use solvents during reactor cleaning top the list of the pharmaceutical industry's most wanted greener processes.

14-May-2007

Merck Generics finds new home with Mylan

After months of speculation and bartering following Merck KGaA's decision to put its generics arm up for sale, the winning bid has finally been announced, with US firm Mylan Laboratories emerging victorious beating off the competition and sealing the deal for €4.9bn.

Klockner invests in new Indian packaging plant

German packaging company Klockner Pentaplast (KP) is investing more than $20m (€15m) in a new pharmaceutical films manufacturing facility in Aurangabad, India, in a bid to up its presence there.

Roche opens biotech production facility in Basel

Roche has opened a Biotechnology Production Centre at its home base in Basel, Switzerland.

Midatech nanoparticles aiming for the clinic in 2008

Midatech, the UK group exploring the therapeutic and diagnostic applications of nanoparticles as drug delivery vehicles, scaffolds for synthetic vaccines or antibiotics and non-invasive imaging agents, is hoping to put its first product into clinical trials in 2008.

New insights in cancer cell migration

A workshop being held this week in Italy has shed new light on how cancer cells spread around the body, highlighting new strategies for potentially combating the disease.

Goodwin doubles US biomanufacturing space

US-based firm Goodwin Biotechnology said it is about to complete the expansion of its biomanufacturing facility as the number of contracts with biotech companies has jumped in the past two years.

10-May-2007

Wyeth facility gets FDA OK

The US Food and Drug Administration (FDA) has given Wyeth's Puerto Rico manufacturing facility the all clear following a recent re-inspection of the plant.

Product news in brief

LabTechnologist.com brings you its periodic round up of new product releases for use in pharmaceutical and life science laboratories, with new offerings from Invitrogen, Micronit, Nimblegen, Porvair and Qiagen.

Schwarz Parkinson's patch ploughs on

Schwarz Pharma's foray into the central nervous system disorder market is beginning to pay serious dividends as the firm's ground-breaking transdermal patch for Parkinson's continues to prove a success story, now gaining approval in the US market.

Thermo Fisher Scientific launches new cell media

Two new cell growth media for human embryonic kidney (HEK) cells have been launched to aid the discovery and production of various biological drugs.

Lonza plans to commercially produce emerging class of drugs

Lonza is betting on the growth of antibody-drug conjugates as the way-of-the-future cancer treatments by moving to large scale production of the emerging drug class by 2008.

Biotool's safety burner

Swiss-firm Biotool has released a new Bunsen burner, the LabFlame, that features a safety control system as well as automatic ignition and gas cut off.

BASF raises production capacity for THF intermediate

BASF is boosting by 30,000 tons its annual production capacity for the chemical intermediate tetrahydrofuran (THF) at the group's site in Ludwigshafen, Germany.

SAFC adds to biologics portfolio

SAFC Pharma has acquired its third biologic drug contract manufacturer in four years with the aim of further expanding its capabilities in that area.

Germany's BfR pushes for single-generation reprotoxicity test under REACH

Germany's Federal Institute for Risk Assessment (Bundesinstitut für Risikobewertung/BfR) has launched an initiative that it believes could reduce by as many as 2.8m the number of laboratory animals needed to test chemicals for reproductive toxicity under the EU's new REACH regulation.

09-May-2007

Do-Coop hits DMF, cGMP milestones for water-based nanotechnology

Do-Coop Technologies, an Israeli company that uses nanotechnology to create an equivalent of intracellular water as a medium for enhancing existing chemical and biological reagents, reactions and processes, has announced two "significant milestones" for its proprietary Neowater platform.

Pall pushes disposables

As single-use technologies become more and more popular for use in biopharmaceutical manufacturing, Pall is following market demands bolstering its product line by adding a number of disposable products to its portfolio.

Clariant cuts ties with life sciences and contract manufacturing

Clariant has cut its ties with the life sciences industry and will no longer offer custom manufacturing services in this arena after the sale of the last piece of its Lifesciences division.

Hatching hep C hope

Researchers have managed to rear a flock of transgenic hens capable of producing eggs that express remarkably high levels of a protein used for the treatment of hepatitis C, potentially creating a cheaper and more efficient rival to traditional bio-manufacturing techniques.

New pandemic flu vaccine gets EU approval

A new human vaccine to be used in the case of a flu pandemic has gained approval in the EU. The Novartis vaccine, Focetria, will be manufactured containing the offending virus should the World Health Organization's warning system rise to a level 6 alert, signifying that a pandemic has taken hold.

Midatech opens GMP nanoparticles production plant

The UK's Midatech Group has opened what it describes as "the world's first cGMP-grade manufacturing plant for the production of nanoparticles at a scale commensurate with pharmaceutical applications".

People on the move: Pharmaceutical manufacturing

AEterna Zentaris, Eli Lilly and Xcellerex have all had people on the move in the world of pharmaceutical manufacturing.

08-May-2007

Amylin raises investment in long-acting Byetta facility to $400 million

Amylin Pharmaceuticals is expanding significantly on the US manufacturing facility it is building in West Chester, Ohio for a long-acting version of its injectable diabetes drug Byetta (exenatide).

Pall continues patent tussle with Entegris

The ongoing intellectual property tussle between Pall and Entegris continues with Pall claiming Entegris' Impact filter cartridge line infringes four Pall patents.

The missing link between microfluidics and MS

A new device has been designed that could form the link between microfluidic separations and mass spectrometry (MS) based proteomics to give faster results from smaller sample sizes.

Industry news in brief

LabTechnologist.com presents its periodic round up of recent industry news with new developments at Beckman Coulter, Thermo Fisher Scientific, Millipore, GE Healthcare and 454 Life Sciences.

Contract packagers in demand, although the times, they are a changin'

Reliance on contract packaging staff is increasing and it is currently a 'contractor's market.' However, the biggest challenge in a packaging laboratory - stability - will only be overcome as full-service packaging firms take over the scene, attendees heard during a recent presentation at Interphex, New York.

Wockhardt reinforces European presence with Negma acquisition

Indian biopharmaceutical company Wockhardt Limited has continued its push into Europe with the all-cash acquisition of France's Negma Laboratories (Negma-Lerads) for $265m (€195.4m).

Avecia paves way for more efficient protein production

The Biologics division of UK company Avecia has launched pAVEway, a new microbial system for producing high yields of a wide range of therapeutically active protein, such as vaccines, cytokines and growth factors.

Genta pushing hard for antisense approval

US biopharma company Genta has outlined how it hopes to gain approval for its antisense drug with a new clinical trial and multiple appeals against regulators.

EMEA launches GMP database

An online database detailing information on all manufacturing and importation certificates and authorisations issued within the European medicines network has been launched by the European Medicines Agency (EMEA).

EMEA to re-examine epoetins over cardiac fears

The European Medicines Agency (EMEA) said it will now re-examine all epoetins approved in the EU after new fears have been raised over cardiac safety.

Solvay sells facilities to contract manufacturer

Solvay Pharmaceuticals has sold two of its manufacturing facilities that it no longer considers as core. The new owners will now act as a contract manufacturer for Solvay, the company announced today.

Applied Microarrays rescues CodeLink

Recently formed Applied Microarrays has rescued GE Healthcare's CodeLink platform and production facility in Tempe, US from closure.

BIO begins in peace

The BIO International Convention in Boston officially began yesterday amid relative peace after concerns over possible large and violent protests failed to materialise.

03-May-2007

One-off costs slice Millipore profits in Q1

One-off costs related to last year's acquisition of Serologicals and a continuing manufacturing consolidation strategy were largely responsible for sharp falls in Millipore's pre-tax and net profits for the first quarter ended 31 March 2007.

New facility for Althea one step closer

Technology and services provider Althea Technologies has stepped closer to a significant increase in manufacturing capacity as it announces the completion of the first phase of construction at its new San Diego facility.

Genentech licenses Sangamos ZFP technology for protein production

Sangamo BioSciences has added Genentech to the list of partners for its proprietary zinc finger DNA-binding protein (ZFP) technology.

Product news in brief

LabTechnologist.com brings you a round up of brings you a round up of some of the latest releases for use in pharmaceutical and life science laboratories from Dowpharma, Genevac, Guava, Olympus, PerkinElmer, Symantix and Thermo Fisher Scientific.

Bosch plans to snap up Pharmatec

The Bosch Group has announced plans to augment its packaging technology division with the acquisition of German firm Pharmatec.

VWR changes hands again

VWR's parent company has signed a definitive agreement to sell the world's second largest laboratory supplier after its recent period of significant growth and profitability.

Big bucks for BMS biologics base

Construction has finally begun on Bristol-Myers Squibb's (BMS) new biologics manufacturing facility in Massachusetts, with the company upping its original investment estimates for construction from $660m (€485.7m) to $750m.

Xceleron to accelerate growth further

Not content with doubling its revenues over the past year, Xceleron is pushing for even more growth by hiring new business development personnel.

BioProgress unveils FastWrap technology for rapid tablet disintegration

Specialty pharmaceutical and healthcare company BioProgess has come up with another twist on its tablet coating technology, TabWrap.

Are you in need of the Astech challenge?

UK-based Astech Projects are 'daring' pharmaceutical companies to challenge them to solve their troublesome laboratory automation processes.

Prosonix wins award for SAX

Prosonix and Bath University in the UK have won the Royal Society of Chemistry's (RSC) Innovation award for the development of a tool that enables the manufacture of crystalline pharmaceuticals of specific sizes.

SAFC completes protein purification capacity expansion

SAFC Pharma, the contract manufacturing arm of Sigma-Aldrich, has announced it has completed the construction of two protein active pharmaceutical ingredient (API) facilities at its US manufacturing site.

02-May-2007

New product makes counterfeiting 'virtually impossible'

A new machine developed by US firm Vardex Laser promises to offer a unique solution to the global problem of drug counterfeiting, protecting products right down to the pill itself.

Sanofi-Aventis gets US OK for disposable insulin pen

US diabetics will soon have a new alternative to the predominant needle and syringe method of administering insulin, now that the Food and Drug Administration (FDA) has granted marketing approval to Sanofi-Aventis' Lantus SoloStar.

West Pharma profit lifts 40 per cent despite Tech Group slump

West Pharmaceutical Services reported a 40 per cent increase in operating profit for the first quarter of 2007, despite profits diving 43 per cent in the Tech Group business that makes the delivery device for Pfizer's inhaled insulin Exubera.

Stevanato broadens glass expertise with Optrel acquisition

Italian glassware specialist Stevanato Group has consolidated the engineering side of its business through the acquisition of fellow Italian company Optrel.

Multisorb's latest innovation to leave inhalable meds high and dry

Active packaging specialist Multisorb Technologies is in the midst of developing a new desiccant product that will offer a novel built-in solution to producers of dry powder and metered dose inhalers.

New hope for TB with nano drug delivery

South African researchers have provided a glimmer of hope for the millions of people in the developing world struck down by tuberculosis (TB) by developing a nano-sized drug delivery platform that could make all the difference in the battle against drug resistant forms of the disease.

Biotech M&A recipe for success

Pharma companies, desperate to fill their drying out pipelines, have shifted from inking licensing deals with biotech firms to buying entire companies as it proves cheaper, a Cambridge conference has heard.

Molecular syringe delivers drug into cells

A 'homing' protein fragment that can track down tumours in the body has been developed to deliver imaging agents or anticancer therapies to cells.

Novo Nordisk ploughs $200m into Brazilian insulin plant

Danish drugmaker Novo Nordisk is investing $200 million (€146.5m) in a major expansion of its insulin production facilities in Montes Claros, Brazil.

Follow-on biologics 'not substitutable', says BIO

The US Biotechnology Industry Organisation (BIO) has fuelled even further the ongoing debate over the potential approval path for follow-on biologics in the country with the release of a white paper this week that stressed that 'generic' versions of these drugs can only be comparable and not identical.

Genentech hails novel approach for facility award

Genentech used Interphex 2007 in New York to hail a novel approach used to build its latest facility - which allowed it to deliver the project on time and under budget and scoop an industry award in the process.

01-May-2007

Suppliers see solid growth in 2007

Laboratory equipment manufacturers are having a good start to 2007, with Thermo Fisher Scientific, Applied Biosystems, Waters, Varian and PerkinElmer nearly all achieving double-digit revenue growth.

Industry news in brief

LabTechnologist.com presents its periodic round up of recent industry news with new developments at Agilent, Beckman Coulter, Carl Zeiss, DuPont, Luminex and PerkinElmer.

Electroacoustic DNA chip synthesis

A new tool for creating DNA microarrays using a directional acoustic droplet ejector has been developed that circumvents the problem of blocked nozzles when using inkjet printing techniques.

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