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28-Feb-2005
Alliance plans to improve polyketide production
28-Feb-2005 - UK-based biotechnology firm Biotica Technology and the University of Cambridge have secured funding for a collaborative research initiative into new expression systems for the production of polyketides.
Japan's Daiichi, Sankyo confirm merger plans
28-Feb-2005 - The rumours of a marriage between Japanese drugmakers Sankyo and Daiichi Pharmaceutical were confirmed on Friday, when the two companies officially announced their intention to merge in a stock deal...
Superfos hikes its pharma capacity
28-Feb-2005 - Having opted to hang onto its pharmaceutical packaging business instead of selling it off, Denmark's Superfos has now expanded the production capacity of the unit 'to extend its position as...
Pharmacogenomics to replace pharma's business model
28-Feb-2005 - Pharmacogenomics will alter the balance of power in the way drugs are developed, tested, marketed and prescribed during the next decade, and the blockbuster business model of big pharmaceutical companies...
Chugai rejigs manufacturing with plant closures
28-Feb-2005 - Japan's Chugai Pharmaceutical is planning to slash the number of manufacturing plants it operates in Japan in the wake of its alliance with Switzerland's Roche in 2002.
25-Feb-2005
Nano-enabled drug discovery set to dominate
25-Feb-2005 - Nanotechnology for molecular targeting and drug delivery is set to become a trillion-dollar industry, fuelled by the pharmaceutical industry, which faces increasingly challenging market conditions. This has lead to an...
Pharma R&D investment tops €29.3 billion
25-Feb-2005 - New statistics released today show that total US investments in R&D made by the biotechnology and pharmaceutical industry topped $38.8 billion (€29.3 billion) during 2004. This beats the $34.5 billion...
Suicidal cancer cells sustained by protein
25-Feb-2005 - Researchers have found a protein, which plays a significant role in colorectal carcinoma. The protein blocks the ability of tumours to activate a natural self-destruct mechanism that would clear the...
24-Feb-2005
Agilent introduces first HPLC-Chip/MS System
24-Feb-2005 - Agilent Technologies has introduced the first high-performance liquid chromatography (HPLC)-chip/mass spectrometry (MS) system for protein identification. This breakthrough microfluidics-based LC/MS technology is expected to significantly increase the speed, ease and...
EU firms sign voluntary biodegradability standard
24-Feb-2005 - A consortium of companies producing biodegradable and compostable polymers for packaging has committed itself to guaranteeing an efficient biodegradeability standard across the EU.
Pharma 'fastest-growing packaging sector'
24-Feb-2005 - Worldwide demand for packaging equipment for the pharmaceutical and personal care products sector is forecast to post the strongest gains of any market through 2008, reaching $4.4 billion in that year.
Codexis buys biocatalyst company Juelich
24-Feb-2005 - US company Codexis has acquired Germany's Juelich Fine Chemicals, one of Europe's leading producers of specialty enzymes or biocatalysts for the production of chiral pharmaceutical intermediates.
Nanotechnology meets bioprocessing
24-Feb-2005 - Japanese company GSI Creos has unveiled the first prototype of a new cell culture reactor that uses nanotechnology to support the growth of more cells than conventional reactors. The bioreactor...
BioPartners taps UK firm for needle-free injector
24-Feb-2005 - BioPartners, currently leading the line amongst companies trying to bring copies of off-patent biologic drugs to the European market, has licensed a needle-free delivery technology for its human growth hormone...
23-Feb-2005
Proteomics market to reach $17.5 billion by 2009
23-Feb-2005 - According to a recent report, projected sales for the worldwide DNA sequencing and proteomics markets are expected to rise at an average annual growth rate of 17.6 per cent from...
Croda focus on added value driving profits
23-Feb-2005 - UK speciality oils supplier Croda International said sales to cosmetics and supplement customers rose 8 per cent last year, helped by expanded capacity in fish oil concentrates and new product launches.
Unisys, GenuOne team up on healthcare traceability
23-Feb-2005 - Unisys has signed an agreement with Boston, US-based GenuOne to provide product tracking and authentication software to the healthcare and life sciences industries.
Researchers discover tumour resistance mechanism
23-Feb-2005 - Researchers in the US have shed light on how tumours acquire resistance to kinase inhibitors. The discovery may help explain the acquired resistance observed in chemotherapy, which currently blights existing...
Serologicals buys media firm to hike stem cell focus
23-Feb-2005 - Serologicals has continued its acquisitive streak, buying the cell culture business Specialty Media from Sentigen Holding Corp, for $6.5m (€4.9m) in cash. The unit will be integrated into Serologicals' Chemicon...
UK RFID/bar code pilot study concluded
23-Feb-2005 - A pilot project aimed at combating pharmaceutical fraud using a combination of radiofrequency identification (RFID) tagging and bar coding, set up by UK firm Aegate last November, has come to...
Malvern: viscosity add-on for Zetasizer Nano
23-Feb-2005 - Malvern Instruments of the UK has launched a new viscometer accessory for its Zetasizer Nano particle characterisation system that should improve the ability of the instrument to study emulsions and...
22-Feb-2005
Protein production in birds moves a step closer
22-Feb-2005 - A rooster has been genetically modified to make an antibody to treat skin cancer in its blood, the first stage in a project that aims to use birds as biological...
Japan's Sankyo and Daiichi to merge?
22-Feb-2005 - Rumours abound that Sankyo, Japan's second largest pharmaceutical company, is in late-stage discussions with sixth-ranked Daiichi Pharmaceuticals over a merger.
Lab scale jet mill launched into UK pharma market
22-Feb-2005 - UK processing and packaging machinery specialist Isopak has added to its product range with a spiral jet mill - intended for pharmaceutical laboratories and R&D departments - that can micronise...
Pliva to work with Mayne on generic biologics
22-Feb-2005 - Croatia's Pliva, the largest pharmaceutical company in Eastern Europe, has teamed up with Australia's Mayne Pharma to hasten the development of two 'generic' biologic drugs.
21-Feb-2005
Starch excipient is soft on tabletting machinery
21-Feb-2005 - Cerestar Food & Pharma Specialties Europe has launched an excipient that it claims allows tablets to be produced using lower compression force, which should result in reduced wear and tear...
Cancer pre-treatment improves drug delivery
21-Feb-2005 - Spectrum Pharmaceuticals has licensed a new technology that could enhance the delivery of drugs to tumours, improving the treatment of solid cancers while also reducing side effects.
Cyclacel solve 3-D structures of PCNA complexes
21-Feb-2005 - Cyclacel researchers and collaborators have solved the 3-D atomic structure of human Proliferating Cell Nuclear Antigen (PCNA), a protein involved in cancer. The discovery should prove crucial in designing and...
Pharma and biotech industry thriving in 'new' EU
21-Feb-2005 - The pharmaceutical and biotechnology industries in the 'new' EU countries are rapidly expanding, presenting considerable potential, although parallel imports remain a challenge.
Sandoz wrests top generic slot from Teva
21-Feb-2005 - The consolidation of the generic drugs industry continues, with Novartis' unit Sandoz merging with two companies that will bring it back into the number one position in the sector.
People on the move
21-Feb-2005 - In-PharmaTechnologist.com presents a round up of personnel moves in the pharmaceutical sector, including the executive line-up at soon-to-be number one generics company Sandoz.
18-Feb-2005
Researchers identify target for cancer drugs
18-Feb-2005 - Researchers have presented findings, which go some way in understanding a communication pathway inside of cells that contributes to development of brain and prostate cancers. The discovery may present drug...
GPhA urges FDA to support generic drugs
18-Feb-2005 - The Generic Pharmaceutical Association (GPhA) has praised the Food and Drug Administration for validating the science of generic biopharmaceuticals and making significant progress in establishing requirements to approve these medicines.
Blowers help remove biological hazards
18-Feb-2005 - Bioquell UK has developed the Clarus range of patent protected biodecontamination technology, designed to generate hydrogen peroxide vapour for the surface biodeactivation of micro-organisms such as bacteria, viruses, and fungi.
Integra launches flask for MAbs production
18-Feb-2005 - Integra Biosciences has launched the CELLine disposable flask, which harnesses membrane technology that is suitable for recombinant protein expression and high yield monoclonal antibody production.
17-Feb-2005
Boehringer Ingelheim Austria named top CMO
17-Feb-2005 - Boehringer Ingelheim Austria has been selected to win a Technology Leadership award by Frost & Sullivan for its activities in the contract manufacture of biotherapeutic proteins, and particularly plasmid DNA.
Parker Hannifin extends process filter range
17-Feb-2005 - Parker Hannifin has introduced a series of new filter products designed for use in the pharmaceutical processing environment.
Canada's Chromos allies with CMO
17-Feb-2005 - Canada's Chromos Molecular Systems and AppTec Laboratory Services have teamed up to provide the biopharmaceutical industry with a broader range of cell line engineering and contract manufacturing services.
West Pharma buys packaging testing lab
17-Feb-2005 - West Pharmaceutical Services, fresh from the disposal of its drug delivery business, is to acquire Monarch Analytical Laboratories in exchange for cash, assumed liabilities and shares totalling $5.6 million (€4.3m).
Sigma-Aldrich buys Degussa nucleic acid business
17-Feb-2005 - Degussa has agreed to sell its nucleic acid unit Proligo to Sigma-Aldrich for an undisclosed purchase price, on the grounds that it does not have the resources in-house to grow...
16-Feb-2005
Neurodegeneration treatments identified in study
16-Feb-2005 - Researchers in the US have identified several promising drug compounds, which when combined, show the potential to treat Huntingdon's and other neurodegenerative diseases.
Biocompatibles plans next-generation microspheres
16-Feb-2005 - UK company Biocompatibles has teamed up with a microfluidics specialist Q Chip to develop a system to improve the manufacture of microspheres used in drug delivery and medical devices.
Pharma firms evaluate laser marking of tablets
16-Feb-2005 - UK laser marking specialist Sherwood Technology now has two pharmaceutical companies evaluating its DataLase technology, an additive that can be used to mark tablets.
FDA in the dock over drug scandals
16-Feb-2005 - US officials attempted to restore the reputation of the pharmaceutical industry by announcing plans to introduce an independent board, which aims to monitor the safety of drugs on the market.
Big pharma missing nanotechnology opportunities
16-Feb-2005 - A new report reveals that large pharmaceutical companies are investing in less money and people in nanotech than other industries, despite pressure to replace fading blockbuster drugs.
Big pharma missing the nanotechnology boat?
16-Feb-2005 - The top pharmaceutical companies are investing less money and people in nanotechnology than other industries, despite pressure to replace fading blockbuster drugs as fewer drugs come out of the sector's...
Safer cell culture supplement launched
16-Feb-2005 - Recently-formed cell culture specialist Celliance has introduced a new supplement designed to boost the growth of cells used in research and bioprocessing, that does not contain fetal bovine serum.
15-Feb-2005
Drug-resistant HIV puts pressure on industry
15-Feb-2005 - The first documented case of drug resistant HIV has prompted calls to step up HIV drug research after the victim developed full-blown AIDS in just three months.
Thomson offers label conversion to meet new FDA regs
15-Feb-2005 - Thomson Scientific & Healthcare has launched a new service to allow pharmaceutical companies to quickly create and modify drug labels that comply with new US Food and Drug Administration guidance...
Education system fails pharma industry
15-Feb-2005 - The UK education system is failing to provide sufficient high calibre scientists needed for the research-based pharmaceutical industry. The concern is that financial targets have meant university science departments becoming...
Scientists discover signal KO's cause diabetes
15-Feb-2005 - US scientists have demonstrated that by knocking out two key signals in liver cells causes diabetes. These findings pave the way for drug strategies to boost these two different signals...
Silicon delivery system improves therapy of liver cancer
15-Feb-2005 - A silicon-based drug delivery system, developed by Australian nanotechnology company pSivida, has passed an important proof-of-concept hurdle in a clinical trial involving patients with inoperable liver cancer.
Human microdose trial data encouraging
15-Feb-2005 - As the cost of commercialising drugs continues to spiral, results from a trial evaluating the concept of human microdosing is set to offer great potential in drug development. The pharmaceutical...
Separation tech for oligo research
15-Feb-2005 - Two US companies have teamed up to market a separation technology that could improve the yield, purity and length of oligonucleotide sequences.
Teva reports sales surge in 2004
15-Feb-2005 - Israeli drug and active pharmaceutical ingredients (API) company Teva has reported a sharp increase in sales in 2004, helped in part by last year's $3.4bn (€2.6bn) acquisition of Sicor.
14-Feb-2005
Drug delivery firm Archimedes makes debut
14-Feb-2005 - 'Give me a lever long enough and a place to stand, and I will move the world', said the mathematician Archimedes in 230 BC. In 2005, a new company bearing...
SEC heightens probe into Chiron
14-Feb-2005 - The US authorities have stepped up an ongoing investigation into Chiron after uncovering what is described as 'potential violations of federal securities laws'.
India's drug sector tackles new patent regime
14-Feb-2005 - The Indian pharmaceutical sector has begun its seismic shake-up following the introduction of new laws granting patent protection to medicines on 1 January.
Germany backs nanotech for medicine
14-Feb-2005 - The German government is the latest in Europe to start a programme to support companies and academics working in the emerging field of 'bionanotechnology'.
11-Feb-2005
Antibiotic resistance rises in European regions
11-Feb-2005 - High rates of antibiotic resistance in South and East Europe are higher than in northern Europe because the regions have high rates of antibiotic use, according to a study published...
Studies improve understanding of drug targets
11-Feb-2005 - Researchers have developed a new structural understanding of how the two key subunits of kinases, one of the most important classes of enzymes, work together. kinases have increasingly become prime...
€10 million EU project devoted to biocrystallography
11-Feb-2005 - A €10 million grant from the EU has allowed researchers throughout Europe to advance their research in the field of 'biological crystallography,' which aims to create precise, 3-D "architectural" models...
10-Feb-2005
Merck under fire again over mercury in vaccines
10-Feb-2005 - The bad press surrounding the pharmaceutical industry continues with claims that Merck & Co executives were concerned about infant exposure to mercury in vaccines several years before the US Food...
Lundbeck subsidiary looking at CoQ10 production
10-Feb-2005 - A contract manufacturer of pharmaceutical ingredients could provide supplement makers with new supplies of the antioxidant coenzymeQ10, currently selling for record prices owing to tight supply, reports Dominique Patton.
Particle sizer improved for aerosol drugs
10-Feb-2005 - Material science company Malvern Instruments has teamed up with ImageTherm Engineering to develop a new version of an instrument used to measure the size of droplets in concentrated spray and...
West Pharma completes drug delivery sale
10-Feb-2005 - West Pharmaceutical Services has completed the sale of its drug delivery operations to Archimedes Pharma, a newly formed UK company backed by private equity house Warburg Pincus.
09-Feb-2005
Prion-busting filter to reach Europe in spring
09-Feb-2005 - Pall is gearing up to launch a new filter technology in Europe that can remove prions - the infectious agents that cause mad cow disease and its human form Creutzfeldt-Jakob...
Pharmaceutical firms must innovate faster
09-Feb-2005 - According to a recent survey, leading pharmaceutical firms claim that despite the decline in R&D productivity, scientists are working harder and completing more projects.
Clean-in-place sensor introduced by Emerson
09-Feb-2005 - Emerson Process Management has launched a new sensor device to help pharmaceutical companies ensure that their clean-in-place (CIP) procedures - essential for aseptic processing - are working effectively.
UK to probe pharma regulations
09-Feb-2005 - The pharmaceuticals sector has been highlighted by the UK government's Cabinet Office as one of its priority projects in a review of business regulation.
Adjuvant debuts in new hep B vaccine
09-Feb-2005 - The European approval of a new high-potency vaccine for hepatitis B virus (HBV) marks the debut on the marketplace of a new adjuvant ingredient that can significantly improve the effectiveness...
08-Feb-2005
Alkermes to file first 'homegrown' product
08-Feb-2005 - US drug delivery company Alkermes has entered a new stage in its development as it gears up to file for marketing approval of its own product, rather than applying its...
Lilly takes bar coding to unit dose level for insulin
08-Feb-2005 - In the US, drugmaker Eli Lilly has extended its bar coding to include individual vials of its insulin products, going beyond the requirements of recent labelling legislation aimed at cutting...
India begins its first human AIDS trial
08-Feb-2005 - India begins its first ever human clinical trial of an investigational vaccine candidate designed to treat HIV/AIDS, which now has a worldwide infection rate of 14,000 every day.
2Q profits plunge at Cardinal Health
08-Feb-2005 - Pharmaceutical distribution and technology company Cardinal Health reported a slide in profits in the second quarter of the year, as an internal investigation into the company's accounting practices claimed additional...
Terrorist fears drive bomb detector sales in pharma
08-Feb-2005 - A UK company is finding that the pharmaceutical industry is a lucrative new market for its under vehicle bomb detector, now that terrorist attacks are no longer confined to political...
Substance protects resilient Staph bacteria
08-Feb-2005 - Researchers have identified a promising new drug target in their fight against resilient Staphylococcus bacteria that can be transmitted to patients in hospitals via contaminated medical implants.
Process water analyser launched by Honeywell
08-Feb-2005 - Honeywell has added to its portfolio of sensors and instruments with a dual analyser that monitors and controls process variables in the pharmaceutical and other process industries.
07-Feb-2005
EC takes aim at another chemicals cartel
07-Feb-2005 - The European Commission has charged 18 chemical firms with conspiring to fix prices of hydrogen peroxide and derivatives sodium perborate and sodium percarbonate.
Kemira tilts at number one slot in organic acids
07-Feb-2005 - Finnish chemicals company Kemira is planning to buy Verdugt BV of the Netherlands in a move that will triple its sales of organic acids at a stroke and make it...
Fertin and Perrigo take on US nicotine gum players
07-Feb-2005 - US drugmaker Perrigo has started selling a new nicotine gum to help smokers quit the habit in the US, challenging the dominance there of Pfizer and GlaxoSmithKline's Nicorette product.
Richter Gedeon has mixed fortunes in 2004
07-Feb-2005 - Hungary's Richter Gedeon reported rises in both overall sales and profits in 2004, although its active pharmaceutical ingredient (API) business remained under pressure in the US.
04-Feb-2005
Wyatt demonstrates drug molecular characterisation
04-Feb-2005 - US company Wyatt Technology has demonstrated the importance of macromolecular characterisation in drug discovery using its DAWN EOS detector.
Excipient industry calls for Euro master file system
04-Feb-2005 - The pharmaceutical excipients industry urgently needs a system of European master files, already used by the active pharmaceutical ingredient sector (API), to stimulate innovation in the sector and bring Europe's...
Hana initiates trials of PT-523 for lung cancer
04-Feb-2005 - Hana Biosciences announced today the clinical trial initiation of PT-523 to evaluate this compound as a single agent in relapsed non-small cell lung cancer (NSCLC). Lung cancer continues to carry...
Akzo Nobel profits up on divestment windfall
04-Feb-2005 - Akzo Nobel has reported a sharp rise in profits for 2004, but warned that 2005 would be tough and that further divestments in its chemicals portfolio are planned.
Protein modification technology patented by Bolder
04-Feb-2005 - US firm Bolder BioTechnology has been awarded a patent for a new technology that allows therapeutic proteins to be modified chemically to improve its activity in the body.
Researchers target Alzheimer's enzyme
04-Feb-2005 - Significant progress toward a more targeted treatment of Alzheimer's disease was made as scientists targeted an enzyme, which has a differentiated role and opens up perspectives for new drugs that...
Emergency room bottles lighten load for pharmacists
04-Feb-2005 - Understaffing and heavy workloads are constant problems for hospital pharmacies in the US, but one company believes it has a packaging solution that could speed up dispensing.
Next-gen renin inhibitor results encouraging
04-Feb-2005 - Speedel Experimenta has announced the completion of its human micro-dosing studies into renin inhibitors that are set to provide an effective means of treating hypertension and for protecting end organs...
BASF backs novel encapsulation technology
04-Feb-2005 - Chemicals giant BASF has invested €2 million in a small German encapsulation business that claims to have developed a novel process that allows for efficient ingredient delivery.
03-Feb-2005
MAbs to replace ineffective conventional therapies
03-Feb-2005 - The European monoclonal antibody therapeutics market is set to grow at a compound annual growth rate (CAGR) of 34.1 per cent to $11.4 billion (€8.7 billion) by 2011. The growth...
GPC Biotech starts trials of cancer antibody
03-Feb-2005 - GPC Biotech announced the initiation of a Phase I trial with its anticancer monoclonal antibody, 1D09C3, which has already proved effective in the treatment of lymphoid tumours including non-Hodgkin's lymphoma....
02-Feb-2005
Singapore makes pharma manufacturing output target
02-Feb-2005 - Singapore's manufacturing output recorded 33 per cent growth in 2004, achieving this target one year ahead of schedule and exceeding projected figures compiled in 2000, writes Wai Lang Chu.
Excipient industry's future under debate
02-Feb-2005 - The pharmaceutical industry is under pressure from downwards price pressure, a lack of innovation, and the escalating costs of new product development, and this is having a knock-on effect for...
Pharma industry applauds animal extremism bill
02-Feb-2005 - Pharmaceutical industry groups today welcomed new government legislation, which ensures animal extremists who are found guilty of 'economic damage' to research laboratories will face imprisonment of five years.
Tamper label for sensitive drugs launched
02-Feb-2005 - Germany's Schreiner MediPharm has introduced a new security label, intended specifically for use with syringes filled with heat-sensitive pharmaceuticals.
01-Feb-2005
Millipore product offers easier, faster sterility testing
01-Feb-2005 - Millipore has launched its Steritest EZ testing range for sterility testing of large volume parenterals and synthetic drugs.
New catalyst, but hold the experiments
01-Feb-2005 - Danish researchers have come up with a virtual model for catalyst research that could do away with the need for large, expensive screening experiments.
High volume chromatography media from GE
01-Feb-2005 - GE Healthcare has launched the first in a new family of chromatography media designed specifically to handle the high volumes used in the bioprocessing sector.
PEG makes tablets out of injectables
01-Feb-2005 - NOBEX has been granted two new US patents on its polyethylene glycol (PEG)-based technologies to improve the delivery of drugs that currently need to be injected.
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