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Headlines > January 2005

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31-Jan-2005

Genencor/Danisco tie the knot

31-Jan-2005 - The long-standing relationship between biotechnology company Genencor and Danish ingredients firm Danisco is to be cemented via the merger of the two companies.

Lanxess debuts on Frankfurt exchange

31-Jan-2005 - Lanxess, the chemicals and polymers spin-out of Germany's Bayer, made its debut on the Frankfurt stock exchange this morning.

Acatris launches directly compressible SoyLife

31-Jan-2005 - Health ingredients firm Acatris has developed a directly compressible version of its SoyLife brand soy isoflavone ingredient, designed to remove some of the hurdles for companies looking to offer isoflavone...

UK backs bioprocessing with £3m grant

31-Jan-2005 - The UK government has given the national biotechnology industry trade group £3 million (€4.3m) in funding to support the development of bioprocessing, continuing a string of projects aimed at boosting...

Merck trims down again with electronic unit sale

31-Jan-2005 - Merck KGaA is planning to sell its electronic chemicals business to BASF for €270 million, freeing it up to focus on its pharmaceutical, chemical and liquid crystal businesses.

28-Jan-2005

Neuro3d initiates depression trials with ND7001

28-Jan-2005 - A new type of antidepressant drug with a novel mechanism of action, which acts on a new target, has entered Phase I clinical trials. The drug could represent a new...

Diabetes drug progress promising but slow

28-Jan-2005 - A new potential diabetes drug from Dia-B Tech, which is based on a naturally occurring peptide consisting of four amino acids, promises convenience and fewer side effects over current day...

27-Jan-2005

Neich acquires Orbus Medical Tech

27-Jan-2005 - Neich Medical has acquired Orbus Medical Technologies in which Orbus is leading Neich's research and development efforts for drug eluting stents and other advanced technologies.

Chemical imaging investigated for process monitoring

27-Jan-2005 - The use of chemical imaging as a quality control measure for mixtures of pharmaceutical ingredients before tabletting has taken a step forward with the first deployment of a prototype system...

Bayer plans inhaled Cipro for cystic fibrosis

27-Jan-2005 - Bayer is to collaborate with Nektar on the development of an inhaled formulation of Cipro (ciprofloxacin) for treating the common genetic disorder cystic fibrosis.

Lonza still under pressure in 2004

27-Jan-2005 - Swiss chemicals and contract manufacturing concern Lonza reported a decline in sales but net profit up by more than half in 2004, although earnings came in at the low end...

DNT, Dow & Starpharma in 3-way dendrimer deal

27-Jan-2005 - A unique three-way-deal between Dendritic Nanotechnologies (DNT), The Dow Chemical Company and Starpharma Holdings, will provide DNT and Starpharma with access to dendrimers and nanotechnology for drug delivery.

26-Jan-2005

Pall expands again in chromatography

26-Jan-2005 - Filtration and separation company Pall has made another acquisition in the chromatography sector with the purchase of Euroflow (UK) for an undisclosed amount.

UK National Biomanufacturing Centre on track for '06 start-up

26-Jan-2005 - Construction of the UK National Biomanufacturing Centre, an ambitious project aimed at helping biotechnology start-ups get their product ideas into clinical trials, is progressing on schedule and should be ready...

Transgenic specialist Pharming raises €7m

26-Jan-2005 - Pharming of the Netherlands, which is pioneering the use of transgenic animals for the production of biologics, has raised €7 million in new funding and will use the proceeds to...

Dow spins out dendrimer portfolio to nanotech firm

26-Jan-2005 - Dow Chemical has signed over its entire portfolio of intellectual property and technology in the area of dendrimers - branched polymers with applications in targetted drug delivery - to US...

New active agents against leishmaniasis

26-Jan-2005 - Scientists have targeted the alkaloids of the quinolines chemical family, which have proved effective against visceral leishmaniasis treating this severe form of the disease with its antiparasitic properties.

25-Jan-2005

Cargill to buy out plastics business

25-Jan-2005 - Cargill says it has agreed to acquire The Dow Chemical Company's interest in Cargill Dow LLC, the 50/50 joint venture formed in 1997 to commercialise polylactic acid biopolymers.

Nanotech could be answer to gene therapy delivery

25-Jan-2005 - Researchers in the US have shown that nanoparticles can be used to deliver genetic material into cells safely and effectively, potentially overcoming the primary obstacle to the development of gene...

ALFRED speeds up process R&D at Degussa

25-Jan-2005 - Specialty chemicals company Degussa has developed an put in place an automated workstation that should speed up process development and scale-up projects for its clients.

NIR, Raman set to drive process spectroscopy market

25-Jan-2005 - The global market for spectroscopic equipment used in process monitoring is tipped to grow by 30 per cent between now and 2009, helped by an increasing focus on process analytical...

MIP taking separation tech to commercial scale

25-Jan-2005 - MIP Technologies, a Swedish firm specialising in polymers with binding properties, has signed a deal which could take its technology out of the laboratory sector and into the realms of...

24-Jan-2005

DNA 'glue' improves polymer drug delivery system

24-Jan-2005 - US researchers have developed a faster, more efficient way to produce a wide variety of nanoparticle-based drug delivery systems, using DNA molecules to bind the particles together.

REACH debated ahead of Parliamentary reading

24-Jan-2005 - The European Parliament embarked on a new round of deliberations over the controversial REACH legislation last week, amid intense lobbying by groups representing the chemicals industry, animal rights activists and...

Allos Therapeutics initiates new cancer therapy

24-Jan-2005 - Allos Theraputics have initiated a phase 1 study of its investigational drug PDX (pralatrexate) that has so far proved effective against non-small cell lung cancer (NSCLC). This treatment has the...

Activists having impact on pharma suppliers in UK

24-Jan-2005 - Increasing numbers of suppliers are being forced to stop providing their services to companies and organisations engaged in animal research, according to the Association of the British Pharmaceutical Industry.

Animal extremists' intimidation scares suppliers

24-Jan-2005 - Figures released by the Association of the British Pharmaceutical Industry (ABPI) has revealed that the level of intimidation posed by animal extremists reaches as far as the suppliers who do...

Mixed fortunes in first quarter for Chr Hansen

24-Jan-2005 - Growth in Asian and South American markets boost sales for Danish firm Chr Hansen, counterbalancing a fall in revenue in North America for the first quarter of the year.

EC fines companies for price-fixing cartel

24-Jan-2005 - Three chemicals companies - Akzo Nobel, the Hoechst unit of Sanofi-Aventis and Total subsidiary Arkema - have been fined €217 million by the European Commission for operating a cartel in...

COX-2s: regulatory action to follow?

24-Jan-2005 - Regulatory action on the COX-2 inhibitors was still a possibility as the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) held hearings with Pfizer, Merck Sharp &...

21-Jan-2005

Oncogene identified as viable drug target

21-Jan-2005 - The identification of an oncogene, which is associated with cancers such as leukaemia, could lead to the development of targeted molecular therapeutics, controlling cancer development through regulation of the errant...

20-Jan-2005

Pfizer fined in solvent release case

20-Jan-2005 - The world's largest drug company, Pfizer, has been fined $22,500 for failing to properly notify state and federal officials about a chemical release at a Connecticut research and development plant.

New MCC excipient launched by JRS

20-Jan-2005 - Excipient company JRS Pharma, part of the Germany's J Rettenmaier & Sohne Group, has introduced a new gelling agent to stabilise suspensions and emulsions, writes Phil Taylor.

Vietnam takes action against drug fakers

20-Jan-2005 - The drug control authorities in Vietnam are being aided in the fight against counterfeit drugs by a mobile laboratory system developed by the German Pharma Health Fund (GPHF).

Flow-through dissolution pump from Sotax

20-Jan-2005 - Switzerland's Sotax, a specialist in dissolution and physical testing equipment, has introduced a new ceramic piston pump designed for use in flow-through dissolution testing of dosage forms.

Pathway discovery leads to liver drug treatment?

20-Jan-2005 - A new study has revealed the pathway in the learning impairment caused by liver disease may lead to a drug treatment that would restore learning ability and provide a viable...

19-Jan-2005

Sigma-Aldrich to buy cell culture group JRH

19-Jan-2005 - Australia's CSL, the world's largest manufacturer of blood plasma products, has agreed to sell its JRH Biosciences division to Sigma-Aldrich for $370 million (€283m) in cash. JRH makes cell culture...

Sachet packer reaches UK market

19-Jan-2005 - UK packaging equipment supplier Isopak has introduced an all-in-one system designed to eliminate the difficulties of handling and packing pharmaceuticals, foods and cosmetics in sachets.

People on the move

19-Jan-2005 - New Year, new job. Busy times for personnel in the pharmaceutical technology sector, with a series of new appointments. In-PharmaTechnologist.com provides a round-up.

Needle-free injector planned for hGH

19-Jan-2005 - UK company The Medical House has entered into a deal with Swiss biotechnology firm Serono for a needle-free injector system for the delivery of human growth hormone.

Avecia to spin out pharma specialist Reaxa

19-Jan-2005 - Fine and specialty chemicals company Avecia is planning to spin out part of its pharmaceutical technologies portfolio into a new company to be called Reaxa. The move should complete before...

18-Jan-2005

Croda lanolins top leading emollient

18-Jan-2005 - Croda Healthcare's medical grade lanolin ingredient - used in a number of dermatological brands including the top-selling emollient product in the UK - has outperformed the industry standard emollient, petrolatum,...

Wacker-Chemie buys ProThera

18-Jan-2005 - Wacker-Chemie is to acquire German biotechnology company ProThera, based in Jena, to boost its presence in the biologics manufacturing sector. ProThera will now operate as Wacker Biotech.

Plant molecular farming set to boom?

18-Jan-2005 - Despite burgeoning demand for biopharmaceutical drugs, little progress is being made toward the improving efficiency and reducing costs in conventional biomanufacturing processes using microbial or mammalian fermentation systems.

Boston Scientific upgrades drug-eluting stent

18-Jan-2005 - Medical device company Boston Scientific has launched a new cardiovascular stent designed to deliver the drug paclitaxel in 18 countries around the world, stealing a march on arch-rival Johnson & Johnson.

System speeds up texture analysis

18-Jan-2005 - Materials testing specialist Stable Micro Systems has launched a texture analysis device which promises to increase productivity and improve cost-effectiveness where higher volume, repetitive quality testing is required.

17-Jan-2005

Solvias signs another chiral partner

17-Jan-2005 - Fine chemicals company Rohner is to work together with Switzerland's Solvias on the provision of development and manufacturing services for complex active pharmaceutical ingredients (APIs).

Parkinson's website improves data access

17-Jan-2005 - Scientists researching pharmaceutical treatments for Parkinson's disease are invited to submit study information to a new patient website, which is intended to improve access to information on Parkinson's clinical trials,...

Ampac buys into healthcare packaging

17-Jan-2005 - Ampac Packaging is continuing its acquisitive spree into 2005 with the purchase of Flexicon, a maker of flexible packaging materials for the pharmaceutical, medical and other industries.

Aceto reveals 'biogeneric' ambitions

17-Jan-2005 - US chemicals company Aceto has broken cover and is now racing to develop a leading player in the market for generic versions of biologic drugs, even though the regulatory route...

Groupe Novasep merger completes

17-Jan-2005 - The marriage between US chemicals group Dynamic Synthesis and French separations specialist Novasep has been completed, creating what the new company claims is a unique company to serve the life...

Safety Passport scheme extended to pharma

17-Jan-2005 - A new safety training scheme, designed to deliver accredited 'safety passports' for service engineers and other outside contractors working in pharmaceutical, healthcare, toiletries and cosmetics factories has been introduced in...

14-Jan-2005

deCODE submits first-in-class anti-atherosclerosis compound

14-Jan-2005 - Scandinavian biopharmaceutical company deCode Genetics intends to initiate a Phase I clinical trial of the first-in-class treatment of peripheral arterial occlusive disease (PAOD) which represents a promising therapeutic approach to...

Study reveals how cancer-causing protein activates

14-Jan-2005 - Researchers have shed new light on the activation of a protein key to the development of cancers, particularly breast and prostate cancer, the most commonly diagnosed cancers in the United...

13-Jan-2005

DNA fraud-buster aimed at pharma sector

13-Jan-2005 - Applied DNA Sciences, a specialist in the use of DNA as a security and anti-counterfeiting technology, is to work with the US Department of Energy to develop an improved process...

Rosy outlook for generic API sector?

13-Jan-2005 - The market for low-cost generic drugs looks set to be buoyant for the foreseeable future, both in Europe as a whole and in France, according to Hubert Olivier, president of...

Peptide market finally ripening?

13-Jan-2005 - Peptide drugs look like they may finally fulfil their promise, after years of what has largely been disappointment, if figures released in a new market research report prove accurate.

EU puts cash behind nanobiotechnology

13-Jan-2005 - A new European project on the emerging discipline of nanobiotechnology aims to tackle the thorny issue of safety as well as develop new materials for drug delivery and other medical...

Chiron hoping for vaccine plant inspections

13-Jan-2005 - Chiron said yesterday that the UK and US regulatory authorities are expected to conduct a series of inspections of its manufacturing facility in Liverpool, which was forced to cease production...

12-Jan-2005

Thermo unveils FT-IR spectrometer for QA/QC

12-Jan-2005 - Thermo Electron has launched a new FT-IR spectrometer specifically targeted at quality control and assurance laboratories in the pharmaceutical, chemical and polymer industries.

Romaco extends processing product range

12-Jan-2005 - Switzerland's Romaco has introduced a new laboratory scale product that provides vacuum mixing, dispersion and homogenisation and should be of particular value for formulation development in the pharmaceutical and cosmetics...

New TB approach heralds new treatment

12-Jan-2005 - Researchers have uncovered a novel treatment that could prove to be effective against tuberculosis (TB), a disease that has made a comeback due to the emergence of resistant strains of...

mPLC expands into solubility testing

12-Jan-2005 - Microfluidics company Nanostream has introduced a new range of cartridges designed specifically for quantitative applications such as solubility assessment and dissolution testing using its micro parallel liquid chromatography (mPLC) system.

Encap hikes capacity with new premises

12-Jan-2005 - Scottish drug delivery and encapsulation specialist Encap has invested approximately £1.2 million (€1.7m)in new premises in order to boost its manufacturing capacity by 50 per cent.

11-Jan-2005

First licensee near for Crucell's STAR?

11-Jan-2005 - Genentech is currently evaluating Dutch biotechnology company Crucell's STAR technology for the production of antibodies and other proteins, acquired by the latter firm when it bought ChromaGenics last March.

US packager bought by Bear Sterns

11-Jan-2005 - US printing and packaging company John Henry has been acquired by private equity firm Bear Stearns Merchant Banking.

Choice of asthma inhaler 'makes no difference'

11-Jan-2005 - New treatment guidelines have concluded that there are no significant differences between the aerosol therapy devices used for respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD), as...

New player on US bioprocessing scene

11-Jan-2005 - US biotechnology start-up Cytovance Biologics has officially opened for business this month, offering a portfolio of process development services to support biotechnology companies preparing to progress products into clinical development.

ZuChem launches first mannitol sweetener

11-Jan-2005 - US sweetener company zuChem will launch its initial mannitol product in the first quarter of 2005 on the back of the FDA's recent amendment to its legislation governing the sweetener,...

10-Jan-2005

Will FDA's axe fall on COX-2s?

10-Jan-2005 - A new report suggests that recent safety concerns over certain blockbuster drugs, notably Merck's Vioxx (rofecoxib) and Pfizer's Celebrex (celecoxib), has placed the COX-2 inhibitor drug class under intense scrutiny...

Smaller, cheaper wastewater plant from ITT

10-Jan-2005 - A dual-stage membrane bioreactor (MBR) for advanced treatment of industrial wastewater takes up less space and has lower operating costs than conventional activated sludge processing systems.

Vivascience IPO shelved once again

10-Jan-2005 - Germany's Sartorius has decided to call off the initial public offering of Vivascience, which makes products for the analysis and purification of proteins.

Albumin delivery improves breast cancer therapy

10-Jan-2005 - A widely used drug to treat breast cancer has been significantly improved by the use of a new technology that binds it to albumin, a common constituent of human blood.

Roche extends NanoCrystal license

10-Jan-2005 - Ireland's Elan has altered its licensing agreement with Roche to give the Swiss firm expanded access to a technology designed to improve the performance of drugs.

Contact lenses deliver drugs to eye

10-Jan-2005 - Researchers in Singapore have developed a novel way of delivering drugs into the eye - load them into contact lenses.

07-Jan-2005

Rapid proteins expression from insect cells

07-Jan-2005 - NextGen Sciences has licensed a new technology for protein expression from Oxford Brookes University that reduces expression timelines for proteins in insect cells by up to 10 days.

Drug firms to publish all trial data

07-Jan-2005 - In response to accusations of a cover up over negative data and placing patient safety at risk, pharmaceutical companies worldwide have agreed to reveal the results of clinical trial drug...

FDA fast tracks first-in-class HIV drug

07-Jan-2005 - The need for an effective HIV drug became apparent as the US Food and Drug Administration (FDA) granted Fast Track designation to the first in a new class of HIV...

06-Jan-2005

TransPharma and Teva enter drug delivery deal

06-Jan-2005 - TransPharma Medical has entered into collaboration with Teva Pharmaceutical to develop transdermal drug delivery systems. The deal aims to research and develop transdermal delivery of therapeutic drugs such as high...

Pharma gets defensive over biogenerics

06-Jan-2005 - Pharmaceutical companies are set to face stiff competition, as generic forms of best-selling biologic drugs will capture a significant market share. The expiration of drug patents, which expire within the...

Sangamo announces collaboration with Pfizer

06-Jan-2005 - Technology used to enhance a mammalian cell based protein in pharmaceutical production as well as the creation of new production cell lines is the subject of collaboration between Pfizer and...

Ash Stevens manufactures leukaemia API

06-Jan-2005 - The first new leukaemia treatment approved specifically for children in more than a decade was approved as Ash Stevens are to manufacture Clofarabine, the active ingredient in Clolar, used to...

Low cost tumour drug from yew needles

06-Jan-2005 - A new method to produce paclitaxel, the potent anti-tumour drug from yew needles has been discovered which provides a solution to the problem of finding a viable source of the...

05-Jan-2005

UK chemicals industry sees 2005 as a crucial year

05-Jan-2005 - Judith Hackitt, director general of the UK Chemical Industries Association, highlighted the key issues facing the UK sector at a the group's recent council meeting in London.

Process development service tackles QC issue in biopharma

05-Jan-2005 - The rapid growth in the development and commercialisation of new biological entities (NBEs) has been one of the major trends in the pharmaceutical sector over the last few years, but...

SAFC starts work on high potency expansion

05-Jan-2005 - In keeping with the current trend among contract manufacturing organisations to tap into niche markets, SAFC has started construction of a new facility aimed at meeting the demand for manufacturing...

Packaging machinery market to top $31bn in 2008

05-Jan-2005 - World demand for packaging machinery is projected to rise over 4 per cent per year (including price increases) through 2008 to over $31 billion, with developing nations expected to register...

New target identified in osteoarthritis

05-Jan-2005 - Using naturally occurring mutant mice with a defective collagen gene, scientists at Harvard have identified a signalling molecule involved in osteoarthritis, one of the most common causes of disability among...

Drug delivery firm aims to solve NSAID problems

05-Jan-2005 - The withdrawal of Merck & Co's COX-2 inhibitor Vioxx (rofecoxib) because of cardiovascular safety issues - and concerns about the safety of other drugs in the class - have left...

04-Jan-2005

West decides future of drug delivery arm

04-Jan-2005 - West Pharmaceutical Services is to sell a substantial part of its drug delivery business to a newly formed company in return for $7.1 million (€5.3m) in cash and a 14...

Drug and packaging disposal made simple

04-Jan-2005 - Franklin Miller has launched a shredding system designed for the efficient destruction of pharmaceutical materials, making it easier for drug companies, distributors or wholesalers sitting on a pile of expired...

Nanoscale solution to brand protection

04-Jan-2005 - US company NanoInk, which has pioneered the dip pen nanolithography process which can provde nanoscale printing, is reportedly working with the manufacturer of a blockbuster drug to trial the encoding...

New turbidity filter tops membrane performance

04-Jan-2005 - US filtration specialist Argonide has introduced what it claims is a new generation of turbidity filters with a capacity more than 20 times greater than conventional cartridges.

Millipore updates control software for separations

04-Jan-2005 - Millipore has launched a new version of its control software for its separation and purification systems, bringing the package into line with recent regulatory requirements such as the US Food...

03-Jan-2005

Whatman cuts staff post S&S merger

03-Jan-2005 - UK-based separations specialist Whatman has fleshed out its plans in the wake of the acquisition of Schleicher & Schuell, and says it plans to cut 13 per cent of its...

Patheon completes Mova purchase

03-Jan-2005 - Contract manufacturing company Patheon has completed its $350m (€259m)acquisition of Puerto Rican rival Mova Pharmaceuticals, first announced in November.

GE to buy Ionics for $1.1bn

03-Jan-2005 - GE Infrastructure, a business unit of General Electric, is to acquire US water purification and wastewater treatment company Ionics for around $1.1 billion (€813m), plus the assumption of debt.

Pharming buys out transgenics company

03-Jan-2005 - Pharming, a Dutch company specialising in the production of proteins from transgenic animals, has acquired an Australian company to shore up its patent position and technology portfolio in this area.

Fast-track to protein function with new database

03-Jan-2005 - A new Internet-based platform promises to speed up the process of ascribing functions to proteins discovered as a result of genome research.

Production started for IV drug compounder

03-Jan-2005 - ForHealth Technologies has started production of its flagship robotic intravenous drug compounding device through contract manufacturer Delphi Medical Systems.

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