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Headlines > January 2004

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30-Jan-2004

Agilent to roll out first-in-class QA/QC software

30-Jan-2004 - Agilent Technologies has launched a software package to help drug companies keep a close eye on the quality of chemical compounds. The firm says the product is the first of...

Dow swings to profit as revenues surge

30-Jan-2004 - Dow said that increased demand for its products lifted fourth-quarter sales by 20 per cent to $8.3 billion (€6.67bn), well ahead of analysts' consensus estimates of $7.88 billion.

Chr Hansen sales pegged back by dollar

30-Jan-2004 - Danish company Chr Hansen saw its revenues slip 4 per cent in its first quarter, as the impact of the economic downturn and tough dollar exchange rate was felt across...

Algry planning pharma charge

30-Jan-2004 - Spanish manufacturer of choline salts Algry Quimica has signed several new research agreements to develop active ingredients for pharma and food applications.

Euro chemicals gathers momentum

30-Jan-2004 - UK chemical sector growth, including pharmaceuticals, is forecast at 3.6 per cent for 2004, outperforming the 2.3 per cent growth estimated for Europe as a whole, according to a study...

Pros and cons of Sanofi-Aventis link

30-Jan-2004 - Sanofi's hostile bid for larger French rival Aventis may have been rejected, but there are a number of arguments in favour of a link, according to analyst Nicole Lamble at...

29-Jan-2004

Aventis drug linked to five deaths in Japan

29-Jan-2004 - A rheumatoid arthritis drug developed by Franco-German company Aventis has been linked to the deaths of five patients in Japan, prompting the company to warn against prescribing the drug to...

28-Jan-2004

Honeywell to source solvents from Korea

28-Jan-2004 - Honeywell has signed a deal with Korea's SK Chemicals that will expand its production of high-purity solvents in Asia.

Millipore and HyClone link up on 'plastic factory' project

28-Jan-2004 - Millipore has teamed up with HyClone Laboratories in an alliance that brings the concept of disposable factory for biopharmaceuticals production a step closer.

Monsanto strikes back in Solutia dispute

28-Jan-2004 - Monsanto and Pfizer's Pharmacia subsidiary have asked a federal judge to either deny or postpone a request by Solutia to eliminate liabilities to its former parent Monsanto.

Metal detector solves blister pack problem

28-Jan-2004 - A new metal detector capable of picking up ferrous and stainless steel contamination within aluminium foil wrapped products has been developed. Manufactured by German technology firm Sartorius, the product, called...

Tetrionics ramps up potent API business

28-Jan-2004 - Active pharmaceutical ingredient manufacturer Tetrionics is planning to double the capacity at a facility in the US to hike its ability to make highly potent compounds.

Tackling side effects with drug delivery

28-Jan-2004 - A small US company has developed an encapsulation technology for pharmaceuticals that promises to overcome a major healthcare problem - deaths and illness caused by aspirin and other non-steroidal anti-inflammatory...

27-Jan-2004

Strong revenue growth at Millipore

27-Jan-2004 - Filtration specialist Millipore has reported strong growth in sales in the fourth quarter of 2003, suggesting that the fortunes of the biopharmaceutical industry - Millipore's primary customer - may be...

UK chemicals body gears up for REACH

27-Jan-2004 - The Chemical Industries Association in the UK has unveiled plans to develop a database of chemicals marketed in the UK as part of the industry's preparations for the adoption of...

Gradiflow separation passes early test

27-Jan-2004 - Australia's Gradipore has been boosted by news that its Gradiflow separation technology has been scaled up to produce commercial quantities of an antibody from source plasma.

New venture to tackle oral film delivery

27-Jan-2004 - MonoSol has set up a new venture, called MonoSolRx, aimed at developing oral film strip technologies for use in the delivery of drugs.

Crucell names new CEO, trims 2003 losses

27-Jan-2004 - Dutch biotechnology company Crucell has appointed a new chief execvutive as it continues its transition from a company specialising in enabling technologies to one focuused on product development.

Faster, nanoscale HPLC from Eksigent

27-Jan-2004 - Eksigent Technologies is launching a new high-pressure liquid chromatography system in March that can increase throughput compared to rival HPLC systems as much as six-fold.

26-Jan-2004

Pharma tech growing strongly at Cardinal

26-Jan-2004 - Healthcare giant Cardinal Health reported revenues up 11 per cent to $14.1 billion (€11.2bn) in the fourth-quarter of 2003, as a strong performance in its pharmaceutical manufacturing services, pharmacy automation...

New team in chiral alcohols

26-Jan-2004 - Germany's Wacker Specialties has signed an R&D agreement with Finland's Prokaria to bolster its activities in chiral alcohols, used as chemical building blocks by the pharmaceutical industry.

R&D: needs to be big in Japan again

26-Jan-2004 - Japanese pharmaceutical companies must build strong, in-house, R&D capabilities in order to survive, according to research from market analyst firm Datamonitor. But this is not simply a matter of spending...

Sanofi gets hostile with Aventis bid

26-Jan-2004 - French pharmaceutical company Sanofi-Synthelabo has launched a hostile takeover bid for its larger rival Aventis, in a move which would create a top three drug major.

APIs prop up Bachem in 2003

26-Jan-2004 - Switzerland's Bachem saw its 2003 sales slip by 3 per cent as continued slack demand for research chemicals held back a modest increase in its active pharmaceutical ingredients business.

India set to dominate generic API market?

26-Jan-2004 - Last year, pharmaceutical companies from India submitted a third of all the Drug Master Files for active pharma ingredients (APIs) received in the US, outstripping their international rivals by a...

Teva closes SICOR acquisition

26-Jan-2004 - Israel-headquartered generics company Teva Pharmaceutical Industries has completed its $3.4 billion takeover of US company SICOR, which makes generics and active pharmaceutical ingredients.

22-Jan-2004

Elan raises €55m in new sell-off

22-Jan-2004 - Irish pharmaceutical group Elan has raised around $70 million (€55m) from four new deals, including the sale of formulation and manufacturing interests.

Amersham, GE merger on track for April

22-Jan-2004 - General Electric's €8.1 billion acquisition of the UK's Amersham was approved by the European Union yesterday, after it concluded that the deal would not create a monopoly in Europe's medical...

Male contraceptive trials get underway

22-Jan-2004 - Germany's Schering and Organon of the Netherlands have started a Phase II trial of a hormonal implant designed to block fertility in men.

New enzymes for chiral alcohols

22-Jan-2004 - BioCatalytics has expanded its product line of enzymes for chemical synthesis with the addition of new ketoreductases (KRED) enzymes for the stereoselective reduction of ketones.

AstraZeneca extends oral profiling deal

22-Jan-2004 - AstraZeneca has extended an agreement with UK-based Cyprotex to bulk screen whether its drug candidates for suitable for oral administration.

M&A speculation rife in pharma

22-Jan-2004 - If 2003 was marked by consolidation in the biotechnology industry, then in 2004 the spotlight seems to have tracked firmly back to pharmaceuticals - and particularly the European majors.

21-Jan-2004

Avantium broadens chiral technologies

21-Jan-2004 - Avantium Technologies has taken out a license to use Chiral Quest's array of catalysts in its process R&D activities, designed to discover novel ways of making chemicals used in the...

Clariant aims at preformulation

21-Jan-2004 - Clariant has invested in a microfluidisation capability that will allow it to manufacture high performance excipients for film coatings used in sustained- and protected-release active pharmaceutical ingredients.

Packing proteins onto chips

21-Jan-2004 - UK-headquartered NextGen Sciences has formed an alliance with Germany's Protagen aimed at developing 'biochips' that can contain thousands of functional proteins for use in drug discovery.

Girindus posts first profit since IPO

21-Jan-2004 - German contract ingredient manufacturer Girindus posted its first profit since it was floated on the stock exchange in 2000 in the last quarter of 2003, as sales rose 16 per cent to €32 million.

Bespak recovery on track

21-Jan-2004 - Bespak has reported declining sales and profits at its half-yearly results, but said the figures showed that a recovery plan was on track.

Better yields for bioproducts

21-Jan-2004 - Dowpharma has developed new strains of the bacterium Pseudomonas fluorescens that can be used to improve the yield of recombinant proteins made in fermentation vats.

20-Jan-2004

Teva closer to SICOR merger

20-Jan-2004 - Israel's Teva has moved a step closer to consolidating its position as the world's biggest generics manufacturer with the $3.4 billion (€2.7bn) acquisition of US-based SICOR, which makes active pharmaceutical...

Lonza CEO quits as profits slump

20-Jan-2004 - A hoped-for recovery in the second half of 2003 failed to materialise at Lonza, causing the chemicals and custom manufacturing firm to post steep declines in sales and profits for...

Novo expands insulin plant in France

20-Jan-2004 - Denmark's Novo Nordisk is to invest €218 million in a plant to manufacture insulin in Chartres, France, one of the group's largest investments outside its home market.

His-tagging column from Amersham

20-Jan-2004 - Amersham Biosciences has responded to competition in the marketplace for purifying tagged proteins with the launch of Ni Sepharose, a new affinity chromatography medium.

Flow analysis software improved

20-Jan-2004 - Stable Micro Systems will introduce an improved security module for its Exponent software, used in conjunction with its Powder Flow Analyser and other texture analysis instrumentation, designed to make it...

UK falls in line with EU patent law

20-Jan-2004 - The UK government has unveiled plans to modernise its patent rules and bring them into line with the revised European Patent Convention.

19-Jan-2004

Panel seeks industry input on counterfeiting

19-Jan-2004 - A US congressional committee has asked five drug makers for advice on the measures they are taking to combat the counterfeiting and diversion of prescription drugs.

Dr Reddy's extols benefit of shift to drug discovery

19-Jan-2004 - Dr Reddy's Laboratories has developed a new class of therapeutic that could make it the first pharmaceutical company in India to develop a proprietary blockbuster product.

Interest relief helps Solutia struggle on

19-Jan-2004 - Chemicals and drug development company Solutia - forced to file for bankruptcy in the US last year in a bid to shake off liabilities to former parent Monsanto - has...

French firms partner on biocatalysis

19-Jan-2004 - LibraGen, a company specialising in the development of new enzymes to improve manufacturing processes in the pharmaceutical and chemical industries, has teamed up with fellow French firm Synkem.

Rumour of the week: Schering/Novartis

19-Jan-2004 - Last week the talk of the town was Aventis and potential mergers with Sanofi-Synthelabo or Procter & Gamble.

New products bounce back in 2003

19-Jan-2004 - The number of novel pharmaceutical compounds approved for marketing - a traditional benchmark for the industry's R&D performance - has seen a welcome increase after years of declines.

16-Jan-2004

Faster genomics from Caliper, Affymetrix

16-Jan-2004 - Affymetrix and liquid-handling specialist Caliper Technologies - now renamed Caliper Life Sciences - are collaborating on ways of automating genomics research carried out using microarrays.

Roche makes R&D investment in China

16-Jan-2004 - Switzerland's Roche is setting up an R&D centre in Shanghai in a move which reflects the growing importance of the country as both a market for pharmaceutical products and a...

Aventis at heart of consolidation rumours

16-Jan-2004 - Franco-German drugmaker Aventis has seen its share price leap upwards during the week on a resurgence of speculation that it is in the frame for a major merger or acquisition.

Swallowing an underestimated problem in adults, says survey

16-Jan-2004 - A survey has found that difficulties in swallowing pills is widespread among adults, but is rarely discussed with doctors and can prevent some people from taking their medicine. The findings...

Another biocatalyst alliance for Diversa

16-Jan-2004 - Diversa has forged a new alliance for the discovery of bioacatalysts used for the manufacture of pharmaceutical intermediates and active ingredients.

Study slams single-isomer antidepressant

16-Jan-2004 - A recent trend in drug development has been the re-invigoration of older pharmaceuticals by developing new versions based on just one of the two optical isomers of the active compound,...

Bumper year for process development firm

16-Jan-2004 - PTC Organics, a process development company based in the US, says its sales in 2003 doubled over the prior year.

German firms swap antibody tech

16-Jan-2004 - MorphoSys has entered into a cross-licensing deal with fellow German company Bayer Healthcare for technologies used in the development and production of antibody-based drugs.

Genotyping steps up a gear

16-Jan-2004 - Applied Biosystems has launched a new product, based on the combination of a new set of reagents with a software package, that promises to speed up genotyping studies carried out...

15-Jan-2004

BIO in favour of EU 'biosimilar' approach

15-Jan-2004 - The US Biotechnology Industry Organisation has come out in support of European legislation that it says will require extensive tests to be conducted on so-called 'biosimilar' versions of biological drugs.

Rapid-response vaccines from Dow

15-Jan-2004 - Dow Chemical has started a new research product, with the support of the US government, that could hasten the time it takes to make vaccines in response to a new...

Separating the wheat from the chaff in antibody research

15-Jan-2004 - A microarray developed by Protometrix has been used to characterise the interactions between an antibody-based drug and the proteome - a snapshot of all the proteins produced by a cell.

DFB names Phyton president

15-Jan-2004 - DFB Pharmaceuticals has appointed Magnus Precht as the new president at Phyton, a company specialising in plant cell fermentation for the production of pharmaceutical which it acquired last year.

Banning microbes from the lab

15-Jan-2004 - Labcaire of the UK is upgrading its entire range of laboratory safety cabinets by coating them with an antimicrobial treatment designed to minimise the risk of cross-contamination.

Asthma: much more than one disease

15-Jan-2004 - A study which has found significant differences between the adult and childhood forms of asthma suggests that pharmaceutical companies may have to rethink their approach to developing new drugs for...

Bidders gather in MG chemicals auction

15-Jan-2004 - A US-based private equity firm is the latest to join the list of bidders for Dynamit Nobel, the chemicals business being sold by German chemicals and engineering group MG Technologies.

14-Jan-2004

Healthy growth tipped for US chiral technologies market

14-Jan-2004 - The US market for chiral technologies - used to make single isomers of compounds - will grow by an estimated 8.8 per cent a year to reach a value of...

US Medicare reforms under fire

14-Jan-2004 - The US government's attempt to reform the federal Medicare system to provide a prescription benefit for the elderly and disabled has been slammed by the Democrats, who believe it will...

Audit trail eased by peelable labels

14-Jan-2004 - Millipore has developed a new set of labels for its filter products that should make it easier for its biopharmaceutical customers to comply with the obligation to keep accurate batch...

Letting the pack monitor the patient

14-Jan-2004 - Cypak, a Swedish company specialising in novel forms of packaging, has signed what promises to be a major new deal for a 'smart' blister pack system that can detect if...

13-Jan-2004

Breathing new life into old asthma drug

13-Jan-2004 - An ageing drug for asthma marketed by Abbott Laboratories could get a new lease of life from a revamp using drug delivery technology developed by SkyePharma of the UK.

Aprotinin from plants could end supply shortage

13-Jan-2004 - Large Scale Biology Corp has solved the problem of supplying large quantities of aprotinin - widely used in the manufacture of biologic drugs - by developing a recombinant form that...

Non-industry trials under threat in EU

13-Jan-2004 - European clinical researchers have launched a campaign calling on the European Parliament and Commission to repeal a new Directive on Good Clinical Practice (GCP) on the grounds that it will...

Famar buys second Aventis facility

13-Jan-2004 - Aventis Pharma, the French affiliate of the Franco-German Aventis group, has sold its pharmaceutial production and conditioning plant at Saint-Genis-Laval to the Greek company Famar.

New colony picker from Genetix

13-Jan-2004 - Colony counting and picking are well-recognised as one of the most boring, repetitive and error-prone jobs in the lab, and there has been a strong desire to automate the process.

12-Jan-2004

Great Lakes finds buyer for Halebank facility

12-Jan-2004 - UK independent Pentagon Chemicals has made its first major acquisition since spinning out of parent Dow Chemical in a management buyout in 2002, in a move which bolsters its product...

New route to epoxides from Bayer

12-Jan-2004 - Bayer Fine Chemicals has developed a new way to make chiral epoxides that could shorten reaction times and reduce the amount of expensive catalysts used in the process.

First 'druggable' gene kit from Qiagen

12-Jan-2004 - Qiagen of the Netherlands has started shipping a set of RNA interference (RNAi) reagents that correspond to the 5,000 or so genes in the human genome thought most likely to...

Merck deal backs BASF IT Services' independence

12-Jan-2004 - BASF IT Services, one of the first units of the German chemical major to be spun out into a separate unit, has signed an agreement with Merck KGaA that confirms...

Blocking tumour repair could improve therapy

12-Jan-2004 - Researchers in the UK have discovered a protein that seems to play a key role in repairing the DNA of cells. The discovery could lead to a way of inhibiting...

New hands on the helm at UK's TAP

12-Jan-2004 - The Automation Partnership (TAP), a company specialising in the application of robotics to pharmaceutical drug discovery and production, has named a new chief executive to succeed Richard Archer, who is...

Pharma packaging set for continued growth

12-Jan-2004 - World pharmaceutical packaging demand will increase at a rate of 4.3 per cent a year to reach $22.2 billion (€17.2bn) in 2007, according to a new report from Freedonia Group....

Altana to break ground on Cork facility

12-Jan-2004 - German pharmaceutical company Altana has started construction of a €70 million manufacturing facility in Cork, Ireland. The move would appear to refute claims that the attractiveness of the region to...

Small is beautiful for Genentech

12-Jan-2004 - Genentech's strategy of expanding beyond its traditional territory of protein-based drugs and into small molecules was reinforced earlier this week by its new agreement with Array BioPharma.

09-Jan-2004

Tufts gives its answer to drug industry's R&D crisis

09-Jan-2004 - The pharmaceutical industry must cut the time its drugs linger in development and terminate less promising projects earlier if it is to improve the efficiency and productivity of its R&D...

Meeting explores industrial biotech potential

09-Jan-2004 - A new exhibition to be held in the spring aims to look at how industrial biotechnology is being used to transform chemical synthesis and other industrial processes.

Parsons expands in Europe

09-Jan-2004 - MW Consultants, a small Irish company specialising in engineering and construction in the pharmaceuticals industry has been acquired by US firm Parsons Corp.

08-Jan-2004

Flu vaccine deal lifts Crucell

08-Jan-2004 - Dutch biotechnology company Crucell has won a major new contract for its PER.C6 cell line technology from Aventis Pasteur, which will use it for the development and production of flu...

A faster way to pure proteins

08-Jan-2004 - The Automation Partnership has launched a new robotic system designed to take the legwork out of extracting proteins made in microbial or insect cells.

Akzo CEO says 2004 will be tough

08-Jan-2004 - Although there are some signs of an economic recovery that should help its business, the European chemical and pharmaceutical industry can expect to have another difficult year in 2004.

Japan follows US with bar code plan

08-Jan-2004 - Japan has said that it intends to require all prescription drugs to carry bar codes in a bid to prevent medication mix-ups, but hospitals are worried about the cost implications...

New tool in antibiotics discovery

08-Jan-2004 - A collaboration between Switzerland's Genedata and Bayer of Germany has led to new way of developing assays for antibacterial activity and accelerate the search for novel antibiotic classes.

Bayer wins parallel import victory

08-Jan-2004 - The European Court of Justice in Luxembourg has thrown out allegations by the European Commission that Bayer, the German pharmaceutical firm, had established a cartel agreement with its wholesalers to...

S-P cuts staff as competition bites

08-Jan-2004 - Schering-Plough is to cut 18 per cent of its workforce at a manufacturing plant in Brinny, Ireland, in the face of stiff competition to two of the firm's biologic drugs.

Bribery clampdown by industry

08-Jan-2004 - A voluntary code of conduct designed to prevent pharmaceutical companies offering gifts or other incentives in order to prescribe their products has come into effect in Switzerland.

07-Jan-2004

Diosynth cuts staff in Scotland

07-Jan-2004 - Akzo Nobel unit Diosynth has unveiled plans to cut 70 jobs at its UK subsidiary based in Fife, Scotland, because strong competition from Asian competitors is hitting the business.

New investor to fund LGC expansion

07-Jan-2004 - Senior executives at LGC, a UK-headquartered provider of pharmaceutical reference materials and analytical and diagnostic services, are gearing up for a secondary buyout that will help it to accelerate its...

SPAMI process improves glassware quality

07-Jan-2004 - A prototype machine developed by SPAMI, a subsidiary of Italian glassware company Stevenato, can produce glass containers for pharmaceutical uses that are superior in quality to those made via existing...

Insulin doser cuts nursing costs

07-Jan-2004 - A device designed by Novo Nordisk to help diabetics self-administer insulin has been shown to provide significant cost-savings in a new study.

06-Jan-2004

Pronova sold to private equity group

06-Jan-2004 - Norway's Norsk Hydro has agreed to sell 80.1 per cent of its shares in omega-3 producer Pronova Biocare to Norwegian industrial company Ferd for NOK 165 million (€19.4m).

SkyePharma slips back into red

06-Jan-2004 - UK drug delivery company SkyePharma expects to make a loss in 2003, a disappointing result given that it chalked up its first profitable year just a year earlier, and will...

Add-on for FT4 rheometer

06-Jan-2004 - In 2003, Freeman Technology launched its new-generation FT4 rheometer in Europe for testing the flow properties of powders, an important measurement in the pharmaceutical and chemical industries where most processes...

Plastic alternative to Type 1 glass

06-Jan-2004 - Owens-Illinois has developed a new generation of plastic bottles and vials for pharmaceutical applications that have significant advantages over glass counterparts, including shatter resistance and low rates of damage in...

Aceto buys into bio-derived APIs

06-Jan-2004 - US chemicals firm Aceto has bought the German Pharma Waldhof business from Switzerland's Roche, making its first foray into the market for biologically-derived active pharmaceutical ingredients (APIs).

Cambridge Major expands

06-Jan-2004 - Cambridge Major Laboratories expects to complete construction of a new process R&D and manufacturing facility in the middle of 2004 that will make it one of the largest Good Manufacturing...

Scottish bioinformatics firm goes south

06-Jan-2004 - A Scottish life sciences company specialising in the development of bioinformatics software has been sold to QbioCom, a rival firm based in England, for £1 million.

SARS case confirmed by China, WHO

06-Jan-2004 - Virologists in China have said that a man suffering from fever and a respiratory infection is infected with severe acute respiratory syndrome (SARS), the viral disease that caused nearly 800...

05-Jan-2004

New In-Cap handles small volumes

05-Jan-2004 - Isopak of the UK will be unveiling the latest version of the automatic benchtop In-Cap capsule-filling machine at the Total Solutions show in Birmingham, UK, in the spring.

Track and trace team to tackle pharma

05-Jan-2004 - CCL Label, a US firm specialising in the packaging and labelling of pharmaceutical and consumer products, has forged an alliance that could see so-called 'track and trace' technologies more widely...

Dolly technology goes stateside

05-Jan-2004 - Near-defunct Scottish biotechnology company PPL Therapeutics marked the end of a dreadful 2003 with the sale of its cloning technology which created Dolly the sheep for just £760,000 (€1.1m).

New player in pipette market

05-Jan-2004 - Indian companies may be making great strides in capturing international market shares for bulk pharmaceutical ingredients and generic drugs, but to date they have not made a great impression on...

New Year, new focus for ChiroBlock

05-Jan-2004 - German chemistry specialist ChiroBlock has pulled out of the business of producing and marketing chiral compounds and will focus exclusively on providing chiral research and synthesis services for pharmaceutical and...

02-Jan-2004

SARS rearing its head again?

02-Jan-2004 - There are fears that a renewed epidemic of severe acute respiratory syndrome (SARS) could occur in 2004, after initial tests on a patient with symptoms associated with the disease suggested...

Invitrogen continues down acquisition trail

02-Jan-2004 - Life sciences technology company Invitrogen has entered into a definitive agreement to acquire fellow US firm BioReliance, which specialises in the testing and manufacture of biologic drugs.

First-in-class oral anticoagulant OKed

02-Jan-2004 - AstraZeneca has been granted approval for a new drug - the first in its class - for the prevention of blood clotting complications (venous thromboembolism) in major orthopaedic (hip or...

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