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It’s True: Correct Use Of Ultrasonic Cleaning Really Can Reduce Cleaning Time By More Than 50% - I Holland Limited

01-Jul-2014 - The Raybond company, located in Saint Louis (France), specialises in bonding solutions that are mainly used to secure fastenings on windows and windscreens in cars. These adhesives are produced in a tablet form which is then inserted into a gun...
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A better understanding on gelatin cross-linking: causes, control strategy and regulatory approaches - Softigel

30-May-2014 - Gelatin is a water-soluble protein material that is extensively used in several applications, including food, pharmaceutical and photography, among others. In the pharmaceutical field it is mainly used for manufacturing of hard and soft capsules, gelatin coated tablets and in...
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Bioenhancement: Lipid/Liquid Formulation Scale-Up - Capsugel

14-May-2014 - Lipid-based formulations can provide unparalleled increased bioavailability, and the technology for filling and sealing these formulations in capsules has been optimized. This webinar showcases key considerations (including case studies) required to take these products from feasibility to commercialization.
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‘TSAR≈Predict’ Solves Sticking Problems in Hours - I Holland Limited

02-May-2014 - ‘TSAR≈Predict’ is a revolutionary new service which will put an end to time consuming and expensive field trials by offering a solution to stop tablet tooling sticking problems. TSAR≈Predict was born after the completion a two year TSAR (Tabletting Science...
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PharmaCare® 7 Step Audit and Standard Operating Procedure - I Holland Limited

01-May-2014 - Tablet compression tools are often viewed as consumable items but I Holland believe that just because they are replaceable they shouldn’t be viewed as disposable. We believe that well maintained and carefully stored tools will improve your profitability and the...
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Do you have spores? - Steris

27-May-2014 - Trending analysis of cleanroom environmental monitoring data sometimes shows the presence of spores. These undesirable microbes must be eradicated quickly to reduce the risk to the product being manufactured. When spore formers like the highly resistant “bacillus Cereus or subtilis”...
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Smart strategies for sustained release matrix tablets: Compritol® 888 ATO - Gattefossé Pharma

19-May-2014 - This white paper gives an overview of how Compritol® 888 ATO provides clinically relevant sustained drug release profiles along with biopharmaceutical, formulation and manufacturing advantages.We provide an insight on formulation critical attributes, how Compritol® can be used in a range...
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Excipients for Multilayer Tablets - JRS PHARMA LP

07-May-2014 - Multi-layered tablets bring together differently formulated powder mixtures, which typically contain different APIs, into a single tablet with two or more layers. They offer benefits for overcoming API-API interactions and stability issues, tailoring dissolution profiles, and bringing brand recognition to...
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How glass-forming polymers improve bioavailability / Enhanced oral bioavailability with Soluplus® – case study - BASF SE

26-Mar-2014 - How glass-forming polymers improve bioavailabilityPolymers are essential components of oral solid dosage forms and used as binders, disintegrants or coatings. Given the increase in poorly water-soluble drugs, not only well-known but also specifically designed polymers (e.g. Soluplus®) can be used...
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Role of excipients in design of solid amorphous drug dispersions for delivery of poorly water-soluble drugs - Ashland

10-Mar-2014 - Most new drug candidates suffer from poor water- solubility leading to rate limiting dissolution, slow absorption and limited bioavailability. Solid amorphous drug dispersions are most commonly used improve bioavailability by enhancing drug solubility. The selection of the right solid dispersion...
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Solving your sticking problems with Tabletting Science - I Holland Limited

09-Jan-2014 - This webinar looks at why tablet formulations stick to punch tip faces and how to overcome sticking using punch coatings. We will highlight to tablet manufacturers how quickly a solution can be recommended using I Holland's new TSAR model.
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Embedding Q and R Practice in Pharma Ingredient Manufacture - Corbion Purac

09-Dec-2013 - A growing amount of Q&R applies to creating pharmaceuticals. Pharmaceutical manufacturers prefer ingredients developed with compliance that exceeds legal requirements. As the Q&R landscape evolves and its complexity deepens, it becomes increasingly challenging for pharmaceutical ingredient manufacturers to achieve a...
Download now!Technical / white paper

NEOBEE® MCTs Enhance Pharmaceutical Bioavailability - Stepan Lipid Nutrition

04-Nov-2013 - An efficient solvent for many lipophylic drugs and vitamins, NEOBEE® MCTs emulsify in aqueous environments and help uptake in intestinal cells. They are odorless, tasteless and extremely stable and offer a safe, versatile, affordable and simple solution for many bioavailability...
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New Guidelines for Stabilization of Proteins by Freeze Drying: Formulation and Process Heresy - Baxter

17-Oct-2013 - Over the years a number of informal guidelines or “rules” for the formulation and processing of proteins for freeze-drying have been developed. However, in recent years it has become obvious that some of these rules need modification. In this presentation,...
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Rexam’s new child-resistant ophthalmic and nasal closure : continuing many decades of innovative child-resistant drug packaging - Rexam Healthcare

15-Oct-2013 - The U.S. Consumer Product Safety Commission (CPSC) requires child-resistant (CR) packaging for all products containing imidazolines (vasoconstrictor drugs). All prescription and OTC medications with 0.08 mg or more of imidazolines are impacted. The new regulation will be applicable in December...
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Improving API Stability with Increased Excipient Purity - Croda

14-Oct-2013 - Sensitive or unstable APIs can pose formulating challenges when it comes to ensuring their consistent and safe delivery.  Data indicate that the purity level of an excipient can have a notable influence on the stability of pharmaceutical actives.
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Enhancing Solubility Using Lipid-based Formulation Technology - Capsugel

05-Sep-2013 - Lipid-based formulations (LBF) have become a well-established strategy to improve bioavailability and reduce food effect or variability of poorly soluble compounds. Although awareness of LBF technologies is widespread, systematic science-based formulation approaches are not common. Capsugel's Dosage Form Solutions' team...
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Enhancing Actives Delivery for Optimal Formulation Efficacy - Croda

05-Aug-2013 - Excipients designed to enhance skin penetration can maximize the efficacy of topical formulations.  Through lipid disruption and skin polarity modification, topical penetration enhancers allow for more targeted API delivery.  Fill out the form for more information
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Good Tablet Design - Its impact upon tooling performance, anti-counterfeiting and your brand - I Holland Limited

24-Jun-2013 - This webinar will look at why good tablet design is important and how this can help to eliminate potential tablet making problems. We will examine how marketing / branding can be affected if the demands of tooling performance are not considered
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How a punch and die maintenance SOP improves your profitability and productivity - I Holland Limited

21-Jan-2013 - Tablet compression tools are often viewed as consumable items. I Holland believe that because they are replaceable, they shouldn't be viewed as disposable.  This webinar will explore how a professional maintenance SOP can increase your profitability 

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