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Ranbaxy inks consent decree & prepares for $500m penalty

21-Dec-2011 - Ranbaxy has signed a consent decree with the US FDA and set aside $500m for penalty payments to settle its longstanding dispute.

SE Asia likely source of fake anti-malarials in Africa; study

20-Dec-2011 - Counterfeit anti-malarials containing the Viagra API were probably manufactured in Southeast Asia, researchers found.

Final rule adds manufacturing delay reporting requirements

19-Dec-2011 - Manufacturers of certain critical drugs must report production interruptions to the FDA under a new interim final rule.

Drug quality treaty needed to raise standards, academics say

15-Dec-2011 - A treaty on medicine quality is needed to fix the major public health problem of substandard drugs, according to academics.

EMA calls for Vistide recall over Ben Venue contamination fears

14-Dec-2011 - The EMA has recommended recalling a batch of Gilead’s Vistide manufactured by Ben Venue over particle contamination concerns.

Joint FDA-EMA inspection programme to launch in January 2012

13-Dec-2011 - The FDA and the EMA will begin sharing facility inspection data in their respective territories from January to make better use of resources and reduce drugmakers’ inspection burdens.

UPDATE

Chairman's departure not due to investor pressure says Hospira

13-Dec-2011 - Hospira says Chairman Christopher Begley’s impending retirement is unrelated to quality problems at manufacturing plant or recent investor criticism.

Mettler Toledo says new tech will speed up API fermentation

08-Dec-2011 - Mettler Toledo says its new dissolved oxygen (DO) measuring optical sensors can speed up the API production process and reduce maintenance costs.

Ethiopian quality control lab gains ISO testing accreditation

05-Dec-2011 - The Ethiopian national quality control laboratory has gained ISO accreditation to improve access to safe medicines.

US firm offering modular plant leases as alternative to CMOs

01-Dec-2011 - Biologics Modular is leasing its mobile production facilities to help clients make FDA regulated drugs without fixed plants.

Sepha sees growing demand for cost saving testing tech

01-Dec-2011 - The drug industry's need to improve product quality while reducing production costs is driving global demand for testing technologies according to Sepha.

Virus catching filter helps Novo stop batch tests on live animals

30-Nov-2011 - Novo Nordisk has stopped using living animals in batch quality tests after developing a virus filtration tool for factor VII production.

China-focused USP committee to develop excipient standards

29-Nov-2011 - USP is creating a China-focused East Asia expert committee to develop quality standards for excipients.

FDA anti-adulteration efforts hindered by industry; GAO

28-Nov-2011 - Industry reluctance to share information on economic adulteration is hindering FDA efforts to tackle tainted ingredients, a GAO report found.

EMA recalling oncology drugs manufactured by Ben Venue

23-Nov-2011 - The EMA is recalling cancer drugs manufactured by CMO Ben Venue Laboratories after inspectors found quality shortcomings.

FDA sends Mylan Puerto Rico plant a GMP warning letter

23-Nov-2011 - The US FDA has sent Mylan a warning letter after inspectors found GMP testing failings at its Puerto Rico facility.

Shortages to worsen after Ben Venue suspends manufacture

21-Nov-2011 - Ben Venue Laboratories has voluntarily suspended manufacture at the Ohio plant linked to drug shortages.

“Fear of the unknown” limiting adoption of real-time release testing, FDA says

21-Nov-2011 - Real-time release testing can save money by cutting recalls but “fear of the unknown” is limiting use, a FDA official said.

USP forges closer ties with Chilean drug standards group

15-Nov-2011 - The USP has forged closer bonds with the Chilean Pharmacopoeia Foundation (CPF) in the latest of a series of agreements with regional drug quality groups.

Trust in drug source may blind wholesalers to counterfeits

15-Nov-2011 - Wholesalers’ trust in the quality of products from some countries could decrease vigilance and allow counterfeits to reach pharmacies, research found.

FDA developing QbD examples to ready generic industry for 2013 deadline

10-Nov-2011 - The US FDA is publishing immediate and modified release QbD examples to help generics companies prepare for full implementation in 2013.

K-V prompts FDA investigation into compounding pharmacies

09-Nov-2011 - The FDA is investigating compounding pharmacies’ Makena after K-V Pharmaceutical said they differ from approved forms.

Globalised supply chain drives EMA to rethink batch release

09-Nov-2011 - The EMA plans to update guidance on certification and batch release in response to globalisation of the pharma supply chain.

Chinese FDA should hire CMC staff to boost QbD; Pfizer exec

08-Nov-2011 - The Chinese FDA should hire more CMC reviewers to encourage QbD applications, a Pfizer executive said.

FDA sends Genentech 483 after finding failings at Avastin plant

08-Nov-2011 - The US FDA has sent Genentech a GMP 483 after inspectors found failings in the capping process for Avastin.

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