Breaking News on Pharmaceutical Technology

Product news > QA/QC & validation

Latest news headlines

Products

Suppliers

Big pharma is biggest defrauder

21-Dec-2010 - Big pharma has eclipsed the defence industry as the biggest defrauder of the US federal government under the False Claims Act (FCA), say researchers.

Problems persist at J&J’s Pennsylvania plant, says FDA

16-Dec-2010 - The US FDA said it has found more problems at J&J’s manufacturing facility in Fort Washington, Pennsylvania.

PSM forms affiliate to tackle counterfeits in India

09-Dec-2010 - The Partnership for Safe Medicines (PSM) has established a presence in India to bring together local stakeholders and protect consumers from counterfeit medicines.

Demand for fast QA/QC solutions driving microscopy market, says McCrone Group

08-Dec-2010 - The McCrone Group says pharmaceutical industry need for “quick and dirty” QA/QC solutions in the laboratory and on the factory floor is driving growth of the market for bench-top microscopy.

Commitment to ICH M7 can fix genotoxic impurity issues

07-Dec-2010 - Drafting ICH M7 guidance on genotoxic impurities will require a lot of work from industry and regulators but has the potential to resolve a number of issues.

List of pharma sites vital to US security released by WikiLeaks

06-Dec-2010 - WikiLeaks has published a list of overseas biopharmaceutical facilities considered vital to US national security as part of its release of leaked diplomatic cables.

Metrics discusses benzophenone migration at AAPS

06-Dec-2010 - US Contract research laboratory Metrics reveals that benzophenone, a component used in varnish on labels, is able to migrate through HDPE bottles to reach the pills inside.

bioMérieux exits Portland site production of prepared media, resulting job losses

02-Dec-2010 - bioMérieux will discontinue manufacturing media products for clinical applications and transfer production of other products made at its Portland, US, site elsewhere as part of a restructuring program.

Guidelines needed for inconsistent OTC medication dosing warnings, urge researchers

02-Dec-2010 - Mandatory guidelines for labelling of OTC liquid medication for children should be issued, said researchers who found major inconsistencies in labels and dosage measuring devices.

Counterfeit ACT poses malaria resistance risk

02-Dec-2010 - Counterfeit ACT could support the spread of drug resistant malaria strains from South-East Asia, where chloroquine first became ineffective, to sub-Saharan Africa.

West to add CZ vials as glass QC issues drive interest

01-Dec-2010 - Recognition of glass vial quality issues is supporting interest in West’s analytical capabilities and Crystal Zenith (CZ) products, new sizes of which are being developed, said a company VP.

Monographs, heavy metals and globalisation on USP agenda

01-Dec-2010 - Updating monographs, changing elemental impurity tests and globalisation were discussed by the USP at its workshop and in interviews with in-PharmaTechnologist.

Phase I environmental testing helps waste handling decisions

30-Nov-2010 - Performing environmental testing early in a molecule’s development and including data in tech transfers to CMOs helps ensure there is little mass loading from pilot and commercial plants.

Anti-counterfeiting held back by self-interest & politics

29-Nov-2010 - Narrowly defined pharma self-interest and lack of coordinated political effort means, despite the best effort of some, the problem of counterfeiting may be worsening.

News in brief

J&J recall 9m more Tylenol bottles

29-Nov-2010 - Johnson & Johnson is recalling a further 9m Tylenol bottles in the US after learning of inconsistencies in product label warnings.

Control excipient reactivity with packaging & aluminium lakes

25-Nov-2010 - Aluminium lakes and in-liner packaging can, in some cases, be used to control reactive components in excipients and therefore overcome drug product instability.

ACTA finalised amid claims it creates trade barriers

24-Nov-2010 - ACTA was finalised last week but controversies remain, with research warning it could “create significant barriers to international trade, especially in generic medicines”.

Will & desire needed to drive adoption of real-time release

24-Nov-2010 - The knowledge and means are in place to implement real-time release (RTR), a PAT pioneer said at AAPS, but questions remain about whether pharma has the will and desire.

News in brief

J&J recall children’s Benadryl

23-Nov-2010 - Johnson & Johnson’s McNeil unit has initiated another recall, this time involving 4m packs of Children’s Benadryl allergy tablets and around 800,000 bottles of junior-strength Motrin caplets.

Globalisation is biggest challenge for supply chain security, says USP

22-Nov-2010 - Globalisation is the main challenge to drug supply chain security according to USP scientist Desmond Hunt, who says greater collaboration is the key to maintaining product integrity

Dissolution devise makes ‘dosage dumping’ a thing of the past, says Agilent

18-Nov-2010 - Agilent Technologies has launched its 708-DS Dissolution Apparatus, a quality control instrument that can be set up for manual or automated applications to measure the release rate of an API over time.

Partnerships needed to beat public health counterfeit threat

17-Nov-2010 - Combatting counterfeit drugs through forging stronger partnerships is beyond profit, it is about saving lives, AstraZeneca principal scientist Dr Michael Claybourn told a workshop on global drug quality at the AAPS annual meeting in New Orleans.

USP building database of fake & substandard meds

16-Nov-2010 - The USP is building a database of counterfeit essential medicines to support international drug procurement organisations, such as WHO, and the timely sharing of information between national regulators.

No inspections of heparin sites in China in 20 months pre-crisis

10-Nov-2010 - In the 20 month period before the heparin crisis no Chinese producers were inspected by the FDA and efforts during and since have been hindered by legal and practical challenges.

FDA may be having difficulties in Puerto Rico, says US oversight cmttee

09-Nov-2010 - The US FDA’s Puerto Rico office may be “having difficulty” monitoring drug manufacturing in the country according to the Congressional Committee on Oversight and Government Reform.

Sign up for your free newsletter