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TGA proposes adopting 15 EMA guideline documents

03-Oct-2011 - The Australian TGA is considering adopting EMA guidance on residual solvents, genotoxic impurities and other GMP topics.

FDA takes GMP action against US & Chinese drugmakers

29-Sep-2011 - The US FDA has filed a permanent injunction against a US drugmaker and sent a warning letter to a Chinese API producer following cGMP problems.

Lonza inks stem cell production pact with Mesoblast

28-Sep-2011 - Lonza may build a stem cell production facility dedicated to manufacturing Mesoblast products after inking an alliance.

CMLE OKed to start commercial API production at Netherlands plant

27-Sep-2011 - Cambridge Major Laboratories Europe (CMLE) is set to start commercial API manufacturing at its facility in the Netherlands after approval by Dutch regulators.

ProMetic supplying adsorbent to Chinese biosimilar biz

26-Sep-2011 - ProMetic Life Sciences is supplying an affinity adsorbent to a Chinese biopharm for use in scale-up of a biosimilar.

Crystallisation modelling can improve scale up, PSE says

26-Sep-2011 - Process Systems Enterprise (PSE) has developed crystallisation modelling software to improve throughput and simplify scale-up.

UK drug re-developer sees business in pharma turmoil

22-Sep-2011 - Oxford Pharmascience expects the challenges facing biopharm to drive interest in its drug delivery and reformulation technologies.

FDA hits Indian API plant with warning letter & import alert

22-Sep-2011 - The FDA has issued a warning letter and import alert to an Indian API manufacturer after finding major cGMP failings.

Rx-360 begins audit sharing to raise ingredient quality

21-Sep-2011 - Rx-360 has begun its audit sharing programme to increase knowledge about suppliers and the quality of pharmaceutical raw materials.

Reformulation targeted in FDA unapproved drug plan

20-Sep-2011 - The FDA is targeting companies that reformulate drugs to evade enforcement as it tries to crackdown on the 1000s of products marketed without approval.

Pharma discharge checks called for to protect waterways

20-Sep-2011 - Researchers have called for closer monitoring of pharma manufacturing discharges after detecting endocrine disruption in fish downstream from a Sanofi plant.

News in brief

Berkshire Hathaway completes $9.7bn Lubrizol acquisition

20-Sep-2011 - Chemicals supplier Lubrizol was bought by Warren Buffet’s Berkshire Hathaway group last week in a deal worth $9.7bn (€7.1bn)

Vaccine adverse events linked to virus disrupting ingredient

19-Sep-2011 - Use of deoxycholate to chemically disrupt influenza viruses during vaccine manufacture could be linked to adverse reactions in children, a journal reports.

FDA asks for powers to stop another heparin-like crisis

15-Sep-2011 - The FDA needs additional powers to update its “antiquated, domestically-focused statute” and end the “competitive advantage of non-compliance”, an agency official said.

Albemarle to hike generic API prices on regulatory costs

14-Sep-2011 - Albemarle says it will increase what it charges for generic APIs from next month, citing increasing regulatory and testing costs as the main reasons for the hike.

Lonza MA plant sent FDA GMP warning letter about Eisai API

14-Sep-2011 - The FDA has sent a warning letter to Lonza’s Hopkinton, MA plant after inspectors found faults with how it produces an oncology API for Eisai.

Biocon building Malaysia plant to serve Pfizer insulin deal

14-Sep-2011 - Biocon has begun work on the Malaysian biopharm plant that will serve its deal with Pfizer, and is now providing Lipitor ingredients.

Ingredients & formulation research round up

12-Sep-2011 - in-PharmaTechnologist presents a roundup of recent ingredient and formulation research, including using NIR-CI to check quality and microwaves to formulate ibuprofen.

News in brief

Lonza and Fosun strike up joint venture in Shanghai

12-Sep-2011 - Lonza Group and Fosun Pharmaceuticals will pump $15.6m (100m yuan) into a joint venture in the Zhangjiang High-Tech Industry Zone, China.

Lanxess set to increase thionyl chloride production in Indian facility

12-Sep-2011 - Lanxess have begun plans to increase its production of thionyl chloride by 20 per cent at its plant in Nagda, India.

Cellcura signs HSA-free media deal with IDT for vacc development

07-Sep-2011 - CellCura has inked an agreement with IDT Biologika for the testing and adaptation of its protein-free (PF) media for the production of cell lines for vaccine manufacturing.

Another AmerisourcBergen acquisition; IntrinsiQ for $35m

07-Sep-2011 - AmerisourceBergen has bought informatics firm IntrinsiQ for $35m (€25m) continuing the spending spree it began earlier this week with the acquisition of market access consultancy Premier Source.

DSM and Sinochem’s anti-infective ingredients JV gets green light

01-Sep-2011 - Royal DSM and Sinochem’s anti-infective manufacturing and distribution JV in China has been given the green light by competition authorities.

Lactose giant DMV-Fonterra to buy Indian cellulose excipient maker Brahmar

31-Aug-2011 - DMV-Fonterra excipients (DFE) will buy Indian manufacturer Brahmar Cellulose Private Limited (BCPL) to strengthen its position in the pharmaceutical excipient market and reduce costs.

Wacker expands sales presence in ‘high priority’ Indian market

31-Aug-2011 - German chemical maker Wacker Chemie is ramping up its sales operations in India, with the country’s rapidly expanding pharmaceutical sector being one of its key targets.

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