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FDA revises ICH Q8 guidance

10-Jun-2009 - The FDA has revised its guidance on ICH Q8, adding an annex that clarifies the original document and adds the principles of quality by design (QbD).

RXi presents RNA delivery data

08-Jun-2009 - At TIDES 2009 RXi Pharmaceuticals presented preclinical data on its RNA technologies, including research into sdRNA that is delivered without a vehicle and undergoes spontaneous cellular uptake.

3M’s Taper DPI system makes lactose carrier redundant

04-Jun-2009 - 3M Drug Delivery Technologies has expanded its respiratory drug delivery system offering with its Taper DPI which, it claims, makes carrier compounds unnecessary and will help drug formulators save millions.

Cambridge Theranostics makes bioavailable lycopene pill

03-Jun-2009 - UK researchers have boosted the bioavailability of the tomato skin extract lycopene and produced a pill that they claim can reduce “bad” LDL cholesterol by more than 90 per cent.

Researchers target siRNA delivery

02-Jun-2009 - The latest work on siRNA delivery is focused on in a special edition of Molecular Pharmaceutics, which details the techniques researchers are using to target cells and make more effective therapeutics.

Chocks away for nano prop delivery research?

01-Jun-2009 - US scientists at Harvard University’s Rowland Institute have described a way of making large numbers of controllable nano-propellers that, despite being at an early stage of development, may one day be used to deliver drugs.

Positive Phase III for intranasal cancer pain med

18-May-2009 - Archimedes Pharma has presented positive Phase III results of its treatment for breakthrough cancer pain, NasalFent, which uses the company’s PecSys delivery technology.

West and Vetter team up on new drug reconstitution syringe

11-May-2009 - A new ready-to-use WFI prefilled syringe for the reconstitution of lyophilised drugs is likely to win fans among producers of high-value biopharma drugs according to West Pharmaceutical Services’s VP of European marketing, Mike Schaefers.

Positive Phase I for SurModics’ ocular device

07-May-2009 - SurModics has completed the three year Phase I trial of I-vation TA (triamcinolone acetonide), which uses a novel drug delivery system capable of sustained ocular release of a therapeutic.

Axentis gains ODD for cystic fibrosis related infection treatment

05-May-2009 - Axentis Pharma has received orphan drug designation (ODD) in the US for its cystic fibrosis treatment, which uses liposomes to deliver prolonged high-concentrations of a therapeutic to the infected area.

Lilly & Amylin team up to create diabetes pen

30-Apr-2009 - Eli Lilly and Amylin Pharmaceuticals are jointly developing an exenatide once weekly pen device, which should provide a more convenient way for diabetics to treat themselves.

Nanoparticles used to create topical Viagra rival

29-Apr-2009 - Erectile dysfunction could be treated by a nanoparticle formulation applied directly to the penis, according to research, reducing the side effects that can occur when taking drugs like Viagra.

Sinobipharma claims manufacturing first with capsule perindopril

22-Apr-2009 - Sinobiopharma is seeking a Chinese patent covering the manufacture of capsule forms of the heart drug perindopril, claiming it is the first company in the world to produce the medication in this easy to swallow format.

Zealand licenses Vyteris’ transdermal patch

16-Apr-2009 - The drive to license needle-free delivery methods continues with Zealand Pharma signing a deal to use its peptide optimisation technology with Vyteris’ controlled transdermal patch.

Researchers shed light on MRSA treatment

07-Apr-2009 - MRSA could be treated through a combination of an antimicrobial drug, a peptide and light, according to researchers who have hailed the treatment as a “magic bullet”.

Altea inks deal to use Byetta with PassPort patch

02-Apr-2009 - The search for more convenient diabetes treatments continues, with Altea Therapeutics reaching a $46m agreement with Eli Lilly and Amylin to develop a transdermal patch administering Byetta.

Deal bags Flugen a vaccine delivery micro-device

31-Mar-2009 - Flugen has secured the exclusive rights to Ratio’s novel vaccine delivery technology, which is a disposable micro-device that it claims can improve efficacy and compliance.

Hospira’s “Project Fuel” will cut 1,400 jobs

25-Mar-2009 - US drug delivery specialist Hospira will reduce its workforce by around 10 per cent, or 1,400 employees, over the next 24 months as part of its $140m (€104m) a year “Project Fuel” cost cutting and efficiency drive.

MDRNA signs deal with second Swiss major

24-Mar-2009 - US RNA interference (RNAi) specialist MDRNA has signed a non-exclusive licensing deal granting Swiss drug giant Novartis access to its liposomal siRNA delivery technology platform.

SkyePharma mulls 30% cuts at Lyon Geomatrix plant

09-Mar-2009 - UK drugmaker SkyePharma may reduce the workforce at its production plant in Lyon, France by a third after “long-running” underutilisation of its manufacturing capacity.

Tekmira improves siRNA delivery tech

25-Feb-2009 - The therapeutic index of Tekmira’s SNALP technology, which has been designed to deliver siRNA, has been improved by 5-10 times, according to new data.

Collaboration gives PII transdermal drug delivery tech

19-Feb-2009 - PII has expanded the range of drug delivery solutions it can offer clients through collaboration with NexMed, which gives the contract formulation company access to transdermal technology.

MannKind’s loss mounts ahead of US Afresa submission

18-Feb-2009 - MannKind, one of the inhaled-insulin market’s only remaining players, has posted higher than expected Q4 losses as costs for development of its lead product candidate Afresa increase ahead of its submission to the US FDA.

Hacked wireless delivery devices could release fatal dose

09-Feb-2009 - Researchers have raised concerns that wirelessly activated drug delivery devices could be hacked to steal personal information or release potentially fatal doses of a therapeutic.

EU funds imaging targeted drug delivery R&D

03-Feb-2009 - The EU has backed a €15.9m ($20.4m) research collaboration that will seek to develop drug delivery vehicles that can be tracked through the body with MRI and triggered using ultrasound.

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