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Mejores prácticas para superar los desafío de recubrimiento de capsulas blandas - BASF SE

30-Jul-2014 - Las cápsulas blandas se han convertido en una presentación farmacéutica cada vez más popular  para el suministro de productos farmacéuticos y suplementos dietéticos debido a su capacidad de atraer al consumidor. Sin embargo;  la aplicación de un recubrimiento funcional para...
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BASF Pharma Solutions for Dermal Drug Delivery - BASF SE

03-Jun-2014 - Transdermal drug delivery is an exciting and challenging area. How can skin permeation be improved? What is the key to drug solubilization in transdermal delivery systems? BASF's Skin Delivery platform seeks to provide understanding, solutions and materials for the delivery...
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Smart strategies for sustained release matrix tablets: Compritol® 888 ATO - Gattefossé Pharma

19-May-2014 - This white paper gives an overview of how Compritol® 888 ATO provides clinically relevant sustained drug release profiles along with biopharmaceutical, formulation and manufacturing advantages.We provide an insight on formulation critical attributes, how Compritol® can be used in a range...
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Vcaps ® Plus Capsules - a new high performance HPMC capsule for optimum formulation of pharmaceutical dosage forms - Capsugel

07-May-2014 - A new second generation HPMC capsule has been developed to speed formulation and commercialization timelines in pharmaceutical drug development. Vcaps Plus capsules developed without gelling agents provide HPMC capsules with improved physical and operational performance to match the needs of...
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Maximize Excipient Purity to Optimize Efficacy - Croda

14-Apr-2014 - The purity of your excipient can have a profound impact on your formulation’s performance, affecting both the stability of the drug and the final formulation.  Croda’s Super Refined™ range offers the most highly-purified excipients available, providing the power of purity...
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Film Coating for Taste-masking of an HIV Drug for Pediatrics - Colorcon Inc.

25-Mar-2014 - MSD evaluated several taste-masking options to coat raltegravir granules, for pediatric dosing.  They chose a coating comprised of Surelease®, aqueous ethylcellulose dispersion, in combination with an Opadry® product.  Insoluble in water, ethylcellulose acts as the taste-masking agent by delaying the...
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Dow AFFINISOL™ polymers for Solubility Enhancement - Dow Pharma & Food Solutions

12-Mar-2014 - Dow’s AFFINISOL™ line of excipients include AFFINISOL™ HMPCAS for spray drying applications and AFFINISOL™ HPMC for hot melt extrusion (HME) applications. Hypromellose acetate succinate (HPMCAS) has proven effective at producing stable amorphous solid dispersions for poorly soluble APIs. We will highlight: •...
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Role of excipients in design of solid amorphous drug dispersions for delivery of poorly water-soluble drugs - Ashland

10-Mar-2014 - Most new drug candidates suffer from poor water- solubility leading to rate limiting dissolution, slow absorption and limited bioavailability. Solid amorphous drug dispersions are most commonly used improve bioavailability by enhancing drug solubility. The selection of the right solid dispersion...
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Bioavailability Enhancement Series: Hot-Melt Extrusion - Capsugel

18-Feb-2014 - Hot-melt extrusion (HME) of amorphous solid dispersions is one approach Bend Research uses to address APIs with limited bioavailability due to low solubility and dissolution rates (DCS IIa and IIb). Please join us to discuss solid dispersion formulation selection and...
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Solving your sticking problems with Tabletting Science - I Holland Limited

09-Jan-2014 - This webinar looks at why tablet formulations stick to punch tip faces and how to overcome sticking using punch coatings. We will highlight to tablet manufacturers how quickly a solution can be recommended using I Holland's new TSAR model.
Download now!Technical / white paper

Key to Outsourcing Method Development and Validation: A Pragmatic Approach -

12-Dec-2013 - In an industry that is seeing an increasing level of work being outsourced, alongside a focus for companies to achieve ever shorter timelines to get a new drug to market; it is vital that a tailored, pragmatic approach is adopted...
Download now!Technical / white paper

Mitigating Medication Errors with Tablet Design - Colorcon Inc.

09-Dec-2013 - Medical prescription drug errors by doctors, pharmacists and patients account for 1.5 million incidences of sickness, injuries or deaths in the U.S. each year. Thirty percent of these unnecessary adverse events are attributed to human errors in identifying drugs and...
Download now!Technical / white paper

NEOBEE® MCTs Enhance Pharmaceutical Bioavailability - Stepan Lipid Nutrition

04-Nov-2013 - An efficient solvent for many lipophylic drugs and vitamins, NEOBEE® MCTs emulsify in aqueous environments and help uptake in intestinal cells. They are odorless, tasteless and extremely stable and offer a safe, versatile, affordable and simple solution for many bioavailability...
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New Guidelines for Stabilization of Proteins by Freeze Drying: Formulation and Process Heresy - Baxter

17-Oct-2013 - Over the years a number of informal guidelines or “rules” for the formulation and processing of proteins for freeze-drying have been developed. However, in recent years it has become obvious that some of these rules need modification. In this presentation,...
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Improving API Stability with Increased Excipient Purity - Croda

14-Oct-2013 - Sensitive or unstable APIs can pose formulating challenges when it comes to ensuring their consistent and safe delivery.  Data indicate that the purity level of an excipient can have a notable influence on the stability of pharmaceutical actives.
Download now!Technical / white paper

CONFIDENCE IN BIOLOGICS FORMULATION DESIGN - SGS Life Science Services

07-Oct-2013 - To ensure a long product shelf-life for biopharmaceutical drug products, a stable storage environment is critical. Determination of the optimal environment is initiated early in the development process through preformulation screening. In order to maintain potency and activity of protein...
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Hyaluronic acid is now measured on the Hyasis® scale -

16-Sep-2013 - Hyasis is derived from a state-of-the-art Bacillus-based production process utilizing only water for purification with no animal-derived raw materials and no organic solvents for increased safety. Our dedicated research teams offer unique knowledge on characterization, formulation and modification of hyaluronic...
Download now!Technical / white paper

ACG Whitepaper - Pharmaceutical Capsules: Key Considerations - ACG Worldwide

04-Sep-2013 - Capsules, the most important means of delivering medicine, are also the fastest, simplest, and efficient form of administering pharmaceuticals to patients. However, pharmaceutical companies must consider several interdependent factors to determine which type of capsule to employ - two-piece hard...
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Exploring New Frontiers in Direct to Patient Home Delivery Services for Clinical Trials Materials - Marken

07-Aug-2013 - Exploring New Frontiers in Direct to Patient (DTP) Home Delivery Services for Clinical Trial Materials provides an in-depth look at reasons to consider a DTP solution. Included in the discussion are concerns with the traditional distribution channels, advantages and challenges...
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Enhancing Actives Delivery for Optimal Formulation Efficacy - Croda

05-Aug-2013 - Excipients designed to enhance skin penetration can maximize the efficacy of topical formulations.  Through lipid disruption and skin polarity modification, topical penetration enhancers allow for more targeted API delivery.  Fill out the form for more information

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