Library > Technical Papers
Application note
Metrohm - Metrohm
15-Oct-2012 -
The determination of low-molecular-weight aliphatic amines in interfering matrices is a challenging task because the protonated amines are often poorly retained on the column. This problem is met by applying coupled-column matrix elimination.
Technical / white paper
Biosafety Testing: In Vitro Virus Detection - SGS
09-Oct-2012 -
Regulatory authorities (US FDA and the EMEA) impose stringent limits on the amount of microbial contaminates and impurities present during the manufacturing of biological medicines and vaccines.One area of concern is that the cell substrates used in the production of...
Technical / white paper
BASF’s Hot-Melt Extrusion Compendium – 2nd edition - BASF SE
08-Oct-2012 -
The new edition provides readers with an even better understanding of solid dispersions and the hot-melt extrusion process. It offers an overview of BASF’s polymers, more real-world application data and factors to consider in the formulation process
Data sheet
Rexam Safe'n'Sound® devices: Add premium safety to your prefilled syringes - Rexam Healthcare
02-Oct-2012 -
Available for global markets and all therapeutic areas, Safe’n’Sound® devices by Rexam provide healthcare professionals and patients with a full protection from needle sticks to prevent accidental contamination
Insight guide
Partnering with Your CDMO for CMC Preparation - DPT Labs
26-Sep-2012 -
Collaborative partnering between Contract Development and Manufacturing Organizations (CDMO) and the drug product submission applicants is becoming increasingly important with the emphasis on product design by regulatory agencies.The CDMO can provide the appropriate resources to build the scientific knowledge base...
Data sheet
Radio Ion Chromatography - Metrohm
17-Sep-2012 -
Radio Ion ChromatographyPositron emission tomography (PET) is one of the most powerful noninvasive diagnostic tools for tracing organ functioning. Quality control of the short-lived PET-radiopharmaceuticals is challenging, not least because of the tough time limits, the radiation issue and the near nanomole radiotracer...
Data sheet
Stabilize your API - Croda Health Care
10-Sep-2012 -
Maximize your drug active and overall formulation stability with high purity PEG 400. Croda’s Super Refined® PEG 400 has demonstrated it improves API stability as well as reduces gelatin cross-linking.
Application note
Soluplus® – The Solid Solution - BASF SE
03-Sep-2012 -
Designed especially for solid solutions, Soluplus significantly boosts the solubility and bioavailability of poorly soluble APIs. Find out how Soluplus performed in an in-vivo test – download a recently published scientific poster.
Case study
Efficient production combining smart synthesis & purification - Novasep
20-Aug-2012 -
Molecules reaching the market in the recent years present an ever-growing complexity and purity criteria are more stringent than ever. The right combination of smart synthesis and advanced purification is necessary to meet the demand in a cost-effective and time-efficient...
Data sheet
Looking to improve your drug bioavailability? - Croda Inc
06-Aug-2012 -
API bioavailability can be optimized through enhancing the stability of your API itself and by improving overall oxidative stability of your formulation. Croda’s Super Refined Oils have demonstrated these benefits. Fill the form for more information.
Technical / white paper
COMPENDIUM: Expert advice on solubility enhancement - BASF SE
20-Jun-2012 -
Must-read solubility enhancement compendiumThe result of many years of research, BASF’s solubilization compendium covers basic principles of solubility enhancement, delivering expert advice and practical tips on:
Solubilizing compounds with poor solubility and bioavailability profiles
Creating solid solutions and dispersions
Investigating solubilization efficacy using...
Research study
Check out the latest ExAct issue on solubilization - BASF SE
18-Jun-2012 -
This issue of ExAct is all about solubilization and bioavailability enhancement. Read about innovative solutions such as HME, learn about dissolution testing – and find out how BASF’s products and services can help solve your challenges.
Data sheet
Issues with Cellular Irritation? - Croda
04-Jun-2012 -
Reduce the irritation at the site of injection or application. Croda’s Super Refined Polysorbate 80 has demonstrated significant reduction in polar impurities which result in significant reduction of cellular irritation. Click here for more information.
Technical / white paper
What do physicians think of DPIs? New insights from a recent survey - Capsugel
01-Jun-2012 -
Interest in DPIs as an alternative to traditional pMDIs has burgeoned in recent years following advances in their design and performance. But what do physicians think? In a survey of treating physicians (GPs and lung specialists), there was a general consensus...
Data sheet
IMA welcomes you to Achema 2012 - IMA
28-May-2012 -
Discover our latest solutions for the processing and packaging of pharmaceutical products on show at the forthcoming Achema: a wide range of innovative machines and complete lines to meet all the requirements of the pharmaceutical
Data sheet
Controlled Substances Supply Chain Management: Ensure Compliance and Optimize Efficiency - DPT Labs
18-Apr-2012 -
Controlled substances are highly regulated and must be vigilantly monitored from the laboratory to the marketplace to prevent theft and illicit sale in the black market, a growing trend.In addition to abundant federal and state regulations, increased globalization – with...
Technical / white paper
Kollicoat® Smartseal 30 D: Active Protection - BASF SE
16-Apr-2012 -
Many solid oral dosage forms call for effective taste masking and moisture protection, especially for ODT formulations. Kollicoat® Smartseal 30 D, an aqueous film-forming agent, delivers on both counts and is easy to process. Find out more here.
Technical / white paper
SGS-Lab-Disulfide Bonds…. - SGS
02-Apr-2012 -
The disulfide bond is a post-translational protein modification with significant implications for structure and function. Predicting the disulfide-bonding pattern in a particular protein poses many analytical challenges as outlined in this article.
Case study
Looking to Improve Your Formulation Stability? - Croda
02-Apr-2012 -
Maximize your API and overall formulation stability with high purity PEG 400. Croda’s Super Refined® PEG 400 has demonstrated it improves API stability as well as reduces gelatin cross-linking. Click here for more information.
Technical / white paper
Container Testing: Quantifying Metal Contaminants - SGS
05-Mar-2012 -
With USP <661> colorimetric methods for detecting heavy metal contaminants known to be inadequate at trace levels, SGS conducted experiments to measure the impact of extraction, solvent, and detection techniques using proposed USP <232> methodology.