Library > Technical Papers
Technical / white paper
Strategic and Tactical Benefits of Automated Sample Preparation in Pharmaceutical Development and Quality Labs - SPS Pharma Services
06-Mar-2009 -
Today the pharmaceutical industry is finding ways to implement automated methods to improve laboratory productivity, the quality of analysis, minimize lab investigations, maximize labor and enhance worker safety. This article discusses additional ways in which laboratory automation can pay off...
Technical / white paper
The Importance of Regular In-Lab Checking of Pipettes - Biohit Oyj
09-Feb-2009 -
“I have my pipettes serviced and calibrated twice a year by a professional pipette service company. Why would I need to check my pipettes myself?” This is quite a common question professional service company technicians get asked by pipette users....
Technical / white paper
Discover new ways to improve ODT performance with Fuji F-MELT® system - Fuji Chemical
09-Feb-2009 -
Oral disintegrating tablets (ODT) are becoming increasingly popular due to its ease of administration among all patient groups. The success will depend on technologies that are simple and scalable. The major challenge for the formulators is to develop ODTs that...
Technical / white paper
Challenge of scaleup of High dose-1 - SPI Pharma
13-Nov-2008 -
The application of oral disintegrating technologies to higher dose actives is a natural extension of this ease of delivery dosage form. A number of companies have marketed products into lower dose therapy < 100 mg using delivery nomenclatures including...
Technical / white paper
Building a multilayered shield - Colorcon
28-Oct-2008 -
As part of a multi-layered system to combat counterfeit drugs, innovative and economical authentication technologies can now be applied directly to the dosage.
Technical / white paper
Would you drop safety for your prefilled syringes? - Rexam Pharma
17-Sep-2008 -
Prefilled syringes are subject to numerous shocks from the filling lines, throughout transportation until the final administration to the patient.Rexam evaluated the robustness of its Safe’n’Sound safety device for prefilled syringes within different drop tests conditions, including feeding bowl delivery....
Application note
Sotax and Buchi team up to offer automated tablet testing with NIR - Sotax AG
08-Sep-2008 -
During the tablet manufacturing process, critical physical parameters should be monitored. A combination of technology, experience and resource from SOTAX and Buchi has lead to the development of a unique tablet testing solution for pharmaceutical and related customers
Application note
New Horizons in Toxicity Prediction - Lhasa
31-Jul-2008 -
On December 8th & 9th 2008 The University of Cambridge, UK will host the inaugural Lhasa Limited Symposium, entitled New Horizons in Toxicity Prediction.
Technical / white paper
Breaking the Mysteries Surrounding ODTs - SPI Pharma
16-Jun-2008 -
Many of the targets for Orally Disintegration Tablets are not well defined and some definitions for product design are in the process of being harmonized. This article reviews these development challenges as mysteries one by one and provides solutions to...
Case study
Merck KGaA makes capsules and tablets distinctive - Merck KGaA
21-May-2008 -
Since mineral pearl effect colors received U.S. FDA approval in mid-2006, Candurin® has developed into a market-leading product, adding strong value to Capsugel's business through its application in a complete line of pearlescent hard capsules
Technical / white paper
Automated Dissolution Testing Key Success Factors - Sotax AG
07-May-2008 -
If Qualification of Dissolution Testing Instruments requires expertise automated dissolution may require even more. To be successful, dissolution automation implementation and validation requires some key success factors...
Application note
USP <1217> "Tablet Breaking Force": A New Chapter for Tablet Hardness Testing - Sotax AG
31-Jan-2008 -
The new USP <1217> chapter "Tablet breaking force" in USP 31 NF6 describes important concerns of Tablet Hardness Testing users:
Application note
Transdermal Sufentanil Licensing Opportunity - Aveva
03-Dec-2007 -
Aveva's 7-day sufentanil's advanced technology and patient benefits will enable Aveva and its Partner to capture a significant share of the existing $3.9 billion dollar chronic pain market.
Application note
Reproducible, homogeneous dry dispersions by the Morphologi® - Malvern
03-Dec-2007 -
The Morphologi® G3 automated particle characterization system from Malvern® Instruments is a new analytical tool that provides high quality, statistically significant particle size and shape information.
Case study
Shop floor integration at Novartis Singapore - Werum
22-Nov-2007 -
Read about the integration strategy for recording of all production-related data in a newly-erected pharmaceutical production plant of Novartis. The article provides insights into the high degree of standardization of data communication from the shop floor up to the MES...
Application note
A Review of Dissolution tests with the Flow Through Method - Sotax AG
21-Sep-2007 -
The flow through method (USP-Apparatus 4) for the determination of the dissolution rate / release rate is a convincing alternative to the known stirrer methods, especially for extended release forms and low soluble active ingredients.
Technical / white paper
MES: Increase efficiency - decrease production costs - Werum
23-Jul-2007 -
Manufacturing Execution Systems (MES) optimize processes along the supply chain, improve production quality and are a vital contribution to GMP-Compliance. Learn how to implement an MES solution by various practical examples and detailed background information.
Application note
Integrated Video Monitoring for Dissolution Systems - Sotax AG
09-Jul-2009 -
Automated Dissolution Systems have been used extensively in QC, Analytical R&D and formulation laboratories of the Pharmaceutical industry. Used first as a powerful troubleshooting tool the video monitoring can now record the physical behavior of the dosage form.
Technical / white paper
Manufacturing Execution Systems to Optimize the PharmaceuticalSupply Chain - Werum
21-May-2007 -
The article provides practical advice on how to achieve a successful implementation of an MES solution. Case studies describe successfully installed MES systems and document the benefits gained for companies.
Technical / white paper
Sensitive and selective with IC-MS coupling - Metrohm
21-May-2007 -
The combination of a highly efficient ion chromatograph with a high-resolution mass spectrometer represents a modern detection technique whose strengths lie in its extreme sensitivity and excellent selectivity. IC-MS coupling is also used when matrix effects have to be suppressed...