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Pfizer abandons Ph III Sutent colon cancer study

02-Jul-2009

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Pfizer has pulled the plug on a Phase III trial of its drug Sutent (sunitinib) in colon cancer after it failed to demonstrate improved clinical efficacy over standard chemotherapy.

Sutent, which is cleared for gastrointestinal stromal tumours (GIST) and kidney cancer and generated $847m (€600m) in global sales last year alone, has had a mixed 2009.

In March Pfizer stopped a Phase III of Sutent in a relatively form of pancreatic cancer trial ahead of schedule after the drug provided patients with ”significant benefits” over comparator therapies.

The following month, a late-stage study in breast cancer was abandoned after Sutent failed to demonstrate superiority as a standalone treatment to Xeloda (capecitabine) made by Swiss rival Roche.