Breaking News on Global Pharmaceutical Technology & Manufacturing

BMS pays $125m to Promedior in second 'right-to-buy' option in fibrosis space

01-Sep-2015 - Bristol-Myers Squibb has acquired the rights to buy immunotherapy firm Promedior and could pay up to $1.25bn (€1.1bn) depending on the clinical development of its lead fibrosis product PRM-151.

Scientists build ‘microfish’ robots for controlled drug delivery

27-Aug-2015 - US researchers say 3-D printed microscopic fish robots will allow intelligent drug delivery.

Novo Nordisk to pump $2bn into diabetes network on back of oral GLP-1 milestone

27-Aug-2015 - Novo Nordisk could spend up to $2bn (€1.8bn) on two facilities to support its diabetes portfolio, including an oral long-acting GLP-1 analogue set to enter Phase III trials.

Device advice: Intertek study shows its key to consider devices in formulation development

26-Aug-2015 - Pharma firms developing inhalable drugs often fail to test that their formulations are compatible with their intended delivery devices early enough according to the Intertek team behind research stressing the benefits of early assessment.

Google launches life sci unit as standalone Alphabet company

24-Aug-2015 - Google has announced plans to launch its life sciences team as a standalone unit under its new Alphabet structure.

Unilife whistleblower case blows over; Ex-exec apologises

20-Aug-2015 - An erstwhile whistleblower who accused Unilife of fraud and violating US FDA validation regulations has apologised and withdrawn his allegations.

European firms form JV for protein delivery polymers

11-Aug-2015 - French firm MedinCell and Dutch company Corbion have formed a JV to produce polymers for unusual drug delivery of large and small molecule drugs.

FDA approves first 3D-printed drug

04-Aug-2015 - A private Pennsylvania company says it has made the first 3D-printed drug to be approved by the US FDA.

News in brief

MannKind ups Afrezza production but Sanofi says sales are modest

03-Aug-2015 - MannKind has announced it has opened two extra production lines for inhalable insulin powder Afrezza, its joint venture with Sanofi.

Echo's cannabis API delivery formulation could aid low solubility drugs

30-Jul-2015 - A drug delivery platform which increased the bioavailability of a cannabis-based drug candidate 30% could be used to boost solubility of other APIs, says Echo Pharmaceuticals.

Sanofi Q2 Afrezza sales far from a giant leap for MannKind

30-Jul-2015 - The €3m Afrezza has contributed to Sanofi’s revenues since launch is unlikely to subdue growing concerns from commentators surrounding its partner MannKind which developed the inhalable insulin.

EMD Millipore and celares team to offer PEGylation to biologic makers

29-Jul-2015 - Attaching PEG-chains to biological molecules can increase bioavailability and speed up development of protein-based therapies and biosimilars, says EMD Millipore which has inked a deal with PEGylation firm celares.

Hikma buys B-I generics subsidiary, strengthens position in US market

28-Jul-2015 - Hikma says its $2.65bn acquisition of Roxane Laboratories will make it the sixth largest firm in the US generics space.

Capsugel expanding Encap plant on rising HPAPI demand

23-Jul-2015 - Capsugel is doubling the size of a facility in Scotland to support demand for the encapsulating of drugs containing high-potency active pharmaceutical ingredients (HPAPIs).

West scaling up AZ plant on demand for Smartdose wearable injector

21-Jul-2015 - Demand for West’s wearable injector - which uses the recently-approved Crystal Zenith delivery system - has led to the expansion of a facility in Arizona.

Planes, drones but no automobiles: NASA pilots pilotless plane for drug delivery

20-Jul-2015 - NASA has used a remote control plane and a fleet of drones to deliver drugs in an approach that could help pharma firms get medicines to patients in hard to reach locations.

Celgene boosting immune-inflammatory presence with $7.2bn Receptos deal

16-Jul-2015 - Celgene has shelled out $7.2bn (€6.6bn) to acquire Receptos which is developing an oral lymphocyte trafficking agent for multiple sclerosis and inflammatory bowel disorder.

'Afrezza is not the new Exubera' says MannKind in defence of low sales

08-Jul-2015 - Pfizer’s Exubera may have muddied the waters but MannKind is confident a marketing push can help its inhaled insulin product Afrezza succeed after disappointing early sales.

Crisis, what crisis? Biocorp happy with IPO which it says will help win Big Pharma customers

08-Jul-2015 - Biocorp has raised €8.9m ($9.8m) through an IPO during what it called a period of “deep macroeconomic uncertainty” and has underlined plans to grow its drug delivery tech business internationally.

Oramed talking to new potential partners in China after Guangxi Wuzhou deal collapses

08-Jul-2015 - Oramed is in talks with replacement Chinese investors after Guangxi Wuzhou pulled out of a plan to sell its insulin pill ORMD-0801 in China.

Hovione upping spray drying capacity to support rise in low solubility drugs

08-Jul-2015 - A new unit will up Hovione’s spray drying capacity 20% as it predicts a surge in demand for such a service in overcoming drug solubility issues.

Novo Nordisk exits transdermal deal with Zosana for type 2 diabetes candidate

07-Jul-2015 - Novo Nordisk has ended a development partnership using Zosana Pharma’s microneedle patch system with its GLP-1 analogue semaglutide, currently being investigated in an oral formulation.

Abivax's IPO to fund HIV and hep B pipeline before potential Big Pharma deal

06-Jul-2015 - In France’s largest ever biotech IPO, Abivax has raised €58m ($64m) to continue developing its HIV and Hep B candidates.

Capsugel completes $25m SDD expansion at Bend site

02-Jul-2015 - Capsugel has pledged to continue investing internally in drug delivery R&D after completing construction of a spray-dried dispersion (SDD) commercial manufacturing site in Oregon.

Juniper to make OxSonics' ultrasound particles to aid cancer drug delivery

30-Jun-2015 - Juniper Pharma Services has won a contract to manufacture ‘sono-sensitive particles’ used to aid delivery of cancer drugs into solid tumours for OxSonics.

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