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Breaking News on Global Pharmaceutical Technology & Manufacturing

Echo's cannabis API delivery formulation could aid low solubility drugs

30-Jul-2015 - A drug delivery platform which increased the bioavailability of a cannabis-based drug candidate 30% could be used to boost solubility of other APIs, says Echo Pharmaceuticals.

Sanofi Q2 Afrezza sales far from a giant leap for MannKind

30-Jul-2015 - The €3m Afrezza has contributed to Sanofi’s revenues since launch is unlikely to subdue growing concerns from commentators surrounding its partner MannKind which developed the inhalable insulin.

EMD Millipore and celares team to offer PEGylation to biologic makers

29-Jul-2015 - Attaching PEG-chains to biological molecules can increase bioavailability and speed up development of protein-based therapies and biosimilars, says EMD Millipore which has inked a deal with PEGylation firm celares.

Hikma buys B-I generics subsidiary, strengthens position in US market

28-Jul-2015 - Hikma says its $2.65bn acquisition of Roxane Laboratories will make it the sixth largest firm in the US generics space.

Capsugel expanding Encap plant on rising HPAPI demand

23-Jul-2015 - Capsugel is doubling the size of a facility in Scotland to support demand for the encapsulating of drugs containing high-potency active pharmaceutical ingredients (HPAPIs).

West scaling up AZ plant on demand for Smartdose wearable injector

21-Jul-2015 - Demand for West’s wearable injector - which uses the recently-approved Crystal Zenith delivery system - has led to the expansion of a facility in Arizona.

Planes, drones but no automobiles: NASA pilots pilotless plane for drug delivery

20-Jul-2015 - NASA has used a remote control plane and a fleet of drones to deliver drugs in an approach that could help pharma firms get medicines to patients in hard to reach locations.

Celgene boosting immune-inflammatory presence with $7.2bn Receptos deal

16-Jul-2015 - Celgene has shelled out $7.2bn (€6.6bn) to acquire Receptos which is developing an oral lymphocyte trafficking agent for multiple sclerosis and inflammatory bowel disorder.

'Afrezza is not the new Exubera' says MannKind in defence of low sales

08-Jul-2015 - Pfizer’s Exubera may have muddied the waters but MannKind is confident a marketing push can help its inhaled insulin product Afrezza succeed after disappointing early sales.

Crisis, what crisis? Biocorp happy with IPO which it says will help win Big Pharma customers

08-Jul-2015 - Biocorp has raised €8.9m ($9.8m) through an IPO during what it called a period of “deep macroeconomic uncertainty” and has underlined plans to grow its drug delivery tech business internationally.

Oramed talking to new potential partners in China after Guangxi Wuzhou deal collapses

08-Jul-2015 - Oramed is in talks with replacement Chinese investors after Guangxi Wuzhou pulled out of a plan to sell its insulin pill ORMD-0801 in China.

Hovione upping spray drying capacity to support rise in low solubility drugs

08-Jul-2015 - A new unit will up Hovione’s spray drying capacity 20% as it predicts a surge in demand for such a service in overcoming drug solubility issues.

Novo Nordisk exits transdermal deal with Zosana for type 2 diabetes candidate

07-Jul-2015 - Novo Nordisk has ended a development partnership using Zosana Pharma’s microneedle patch system with its GLP-1 analogue semaglutide, currently being investigated in an oral formulation.

Abivax's IPO to fund HIV and hep B pipeline before potential Big Pharma deal

06-Jul-2015 - In France’s largest ever biotech IPO, Abivax has raised €58m ($64m) to continue developing its HIV and Hep B candidates.

Capsugel completes $25m SDD expansion at Bend site

02-Jul-2015 - Capsugel has pledged to continue investing internally in drug delivery R&D after completing construction of a spray-dried dispersion (SDD) commercial manufacturing site in Oregon.

Juniper to make OxSonics' ultrasound particles to aid cancer drug delivery

30-Jun-2015 - Juniper Pharma Services has won a contract to manufacture ‘sono-sensitive particles’ used to aid delivery of cancer drugs into solid tumours for OxSonics.

Teva pays $35m upfront for implantable drug delivery device partnership

30-Jun-2015 - Generic juggernaut Teva Pharmaceuticals has partnered with Microchips Biotech to use its implantable drug delivery device to improve outcomes for patients on chronic drug therapies.

Chin up: Allergan looks to fat-busting drug with $2.1bn Kythera deal

29-Jun-2015 - Allergan is set to acquire Kythera Biopharmaceuticals for $2.1bn (€1.9bn) and add the recently approved injectable ‘double-chin’ drug Kybella to its facial aesthetics portfolio.

Phos enzyme ID'd using CRISPR may lead to safer cancer meds say researchers

19-Jun-2015 - A newly identified enzyme that modifies secreted proteins could lead to safer cancer drugs and new osteoporosis treatments say scientists.

Biocorp plans IPO to win more Big Pharma device contracts

16-Jun-2015 - Delivery device maker Biocorp has announced plans to go public and list of Paris’ Alternext market as part of an effort to win more Big Pharma deals.

New drug delivery technologies seek to advance personalized oncology treatments

11-Jun-2015 - Ongoing research on two new drug delivery systems could help clinicians more accurately understand how certain tumors react to different treatments, according to the Journal of the American Medical Association .

CSIRO tells of sea shells that protect sensitive cures

09-Jun-2015 - A capsule inspired by the porous structure of seashells has been developed to protect drugs from extreme temperatures and could be used in controlled delivery.

GSK breathes freely as Mylan launches Seretide generic in UK

08-Jun-2015 - GlaxoSmithKline is unconcerned about losing its position in the respiratory market as Mylan launches the first generic version of blockbuster asthma product Seretide in the UK.

MannKind: Social media buzz will propel Afrezza to blockbuster status

04-Jun-2015 - MannKind’s CFO has no doubt Afrezza will be a blockbuster despite a slow start since launch and is adjusting its manufacturing network in preparation.

Bubble delivery can rescue failing drug candidates, says Oxford team

02-Jun-2015 - University of Oxford scientists are saving undeliverable drugs by placing them in gas bubbles for better bioavailability and fewer side effects.

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